Journal article
Target-Controlled Dosing of Remifentanil During Cardiac Surgery Reduces Postoperative Hyperalgesia
Abstract
OBJECTIVE: One of the strategies to attenuate opioid-induced hyperalgesia (OIH) may be to decrease intraoperative doses of opioids by using target-controlled infusion (TCI).
DESIGN: Double-blind and randomized study.
Authors
Richebé P; Pouquet O; Jelacic S; Mehta S; Calderon J; Picard W; Rivat C; Cahana A; Janvier G
Journal
Journal of Cardiothoracic and Vascular Anesthesia, Vol. 25, No. 6, pp. 917–925
Publisher
Elsevier
Publication Date
December 2011
DOI
10.1053/j.jvca.2011.03.185
ISSN
1053-0770
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AcetaminophenAgedAnalgesics, OpioidAnesthesia, GeneralAnesthesia, IntravenousBlood PressureCardiac Surgical ProceduresDouble-Blind MethodDrug Delivery SystemsElectroencephalographyFemaleHeart RateHumansHyperalgesiaMaleMiddle AgedMorphinePain MeasurementPain ThresholdPain, PostoperativePhysical StimulationPiperidinesPostoperative Nausea and VomitingPreanesthetic MedicationRemifentanilSternotomy