Cholesterol, LDL Concept

subject area of

• 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in Adults  Journal Articles
• A Community-Wide Survey of Physician Practices and Attitudes Toward Cholesterol Management in Patients With Recent Acute Myocardial Infarction  Journal Articles
• A Meta-Analysis of Low-Density Lipoprotein Cholesterol, Non-High-Density Lipoprotein Cholesterol, and Apolipoprotein B as Markers of Cardiovascular Risk  Journal Articles
• A Model for Assessing the Cost-Effectiveness of Atorvastatin and Simvastatin in Achieving Canadian Low-Density Lipoprotein Cholesterol Targets  Journal Articles
• A comparison of pravastatin and gemfibrozil in the treatment of dyslipoproteinemia in patients with non-insulin-dependent diabetes mellitus  Journal Articles
• A new method for measurement of total plasma PCSK9: clinical applications  Journal Articles
• Age and Cardiovascular Risk Attributable to Apolipoprotein B, Low‐Density Lipoprotein Cholesterol or Non‐High‐Density Lipoprotein Cholesterol  Journal Articles
• Alirocumab Reduces Total Hospitalizations and Increases Days Alive and Out of Hospital in the ODYSSEY OUTCOMES Trial  Journal Articles
• Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome  Journal Articles
• An Increased Burden of Common and Rare Lipid-Associated Risk Alleles Contributes to the Phenotypic Spectrum of Hypertriglyceridemia  Journal Articles
• Apolipoprotein B, Residual Cardiovascular Risk After Acute Coronary Syndrome, and Effects of Alirocumab.  Journal Articles
• Are the ACC/AHA Guidelines on the Treatment of Blood Cholesterol a Game Changer? A Perspective From the Canadian Cardiovascular Society Dyslipidemia Panel  Journal Articles
• Assessment of the longer-term effects of a dietary portfolio of cholesterol-lowering foods in hypercholesterolemia  Journal Articles
• Association between Vitamin D and Circulating Lipids in Early Childhood  Journal Articles
• Association of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) With Cardiovascular Risk in Primary Prevention  Journal Articles
• Associations between airway hyperresponsiveness, obesity and lipoproteins in a longitudinal cohort  Journal Articles
• Biological, clinical and population relevance of 95 loci for blood lipids  Journal Articles
• Blood pressure and LDL-cholesterol targets for prevention of recurrent strokes and cognitive decline in the hypertensive patient  Journal Articles
• Blood pressure and low-density lipoprotein-cholesterol lowering for prevention of strokes and cognitive decline  Journal Articles
• Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease  Journal Articles
• Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance  Journal Articles
• Cardiometabolic effects of rosiglitazone in patients with type 2 diabetes and coronary artery bypass grafts: A randomized placebo-controlled clinical trial  Journal Articles
• Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients  Journal Articles
• Cardiovascular risk factors and non-invasive assessment of subclinical atherosclerosis in youth  Journal Articles
• Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis  Journal Articles
• Cerivastatin versus branded pravastatin in the treatment of primary hypercholesterolemia in primary care practice in Canada: A one-year, open-label, randomized, comparative study of efficacy, safety, and cost-effectiveness  Journal Articles
• Characterizing Coronary Heart Disease Risk in Chronic Schizophrenia: High Prevalence of the Metabolic Syndrome  Journal Articles
• Cheese Intake is Inversely Associated with LDL Cholesterol in Young Children  Journal Articles
• Cholestatic jaundice associated with lovastatin (Mevacor) therapy.  Journal Articles
• Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease  Journal Articles
• Common Low-Density Lipoprotein Receptor p.G116S Variant Has a Large Effect on Plasma Low-Density Lipoprotein Cholesterol in Circumpolar Inuit Populations  Journal Articles
• Comparison of New Measures of Vascular Function to Flow Mediated Dilatation as a Measure of Cardiovascular Risk Factors  Journal Articles
• Comparison of Risk Factor Reduction and Tolerability of a Full-Dose Polypill (With Potassium) Versus Low-Dose Polypill (Polycap) in Individuals at High Risk of Cardiovascular Diseases  Journal Articles
• Comparison of Utilization of Statin Therapy at Hospital Discharge and Six-Month Outcomes in Patients With an Acute Coronary Syndrome and Serum Low-Density Lipoprotein ≥100 mg/dl Versus <100 mg/dl  Journal Articles
• Comparison of a dietary portfolio diet of cholesterol-lowering foods and a statin on LDL particle size phenotype in hypercholesterolaemic participants  Journal Articles
• Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials  Journal Articles
• Comparison of the short-term efficacy and tolerability of lovastatin and pravastatin in the management of primary hypercholesterolemia.  Journal Articles
• Consumption of a dietary portfolio of cholesterol lowering foods improves blood lipids without affecting concentrations of fat soluble compounds  Journal Articles
• Contribution of Large Region Joint Associations to Complex Traits Genetics  Journal Articles
• Conversion of Low Density Lipoprotein-associated Phosphatidylcholine to Triacylglycerol by Primary Hepatocytes  Journal Articles
• Dark Chocolate Effect on Platelet Activity, C-Reactive Protein and Lipid Profile: A Pilot Study  Journal Articles
• Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice  Journal Articles
• Direct comparison of a dietary portfolio of cholesterol-lowering foods with a statin in hypercholesterolemic participants1–3  Journal Articles
• Discordance analysis of Apolipoprotein B and non-high density lipoprotein cholesterol as markers of cardiovascular risk in the INTERHEART study  Journal Articles
• Do antioxidant vitamins protect against atherosclerosis? The proof is still lacking**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.  Journal Articles
• Does the magnitude of lipid lowering with statin therapy indicate higher intracranial bleeding risk?  Journal Articles
• Effect of Alirocumab on Mortality After Acute Coronary Syndromes  Journal Articles
• Effect of Bile Acid Sequestrants on the Risk of Cardiovascular Events  Journal Articles
• Effect of Fructose on Established Lipid Targets: A Systematic Review and Meta‐Analysis of Controlled Feeding Trials  Journal Articles
• Effect of a Dietary Portfolio of Cholesterol-Lowering Foods Given at 2 Levels of Intensity of Dietary Advice on Serum Lipids in Hyperlipidemia  Journal Articles
• Effect of advanced access scheduling on chronic health care in a Canadian practice.  Journal Articles
• Effect of dietary pulse intake on established therapeutic lipid targets for cardiovascular risk reduction: a systematic review and meta-analysis of randomized controlled trials  Journal Articles
• Effect of serum lipid concentrations on restenosis after successful de novo percutaneous transluminal coronary angioplasty in patients with total cholesterol 160 to 240 mg/dl and triglycerides <350 mg/dl  Journal Articles
• Effect of weight loss on the postprandial response to high-fat and high-carbohydrate meals in obese women  Journal Articles
• Effects of 2 years of hormone replacement upon bone mass, serum lipids and lipoproteins  Journal Articles
• Effects of Extracted Pulse Proteins on Lipid Targets for Cardiovascular Risk Reduction: Systematic Review and Meta-Analysis of Randomized Controlled Trials.  Journal Articles
• Effects of Ezetimibe Add-on to Statin Therapy on Adipokine Production in Patients With Metabolic Syndrome and Stable Vascular Disease  Journal Articles
• Effects of Lipid‐Lowering and Antihypertensive Treatments in Addition to Healthy Lifestyles in Primary Prevention: An Analysis of the HOPE‐3 Trial  Journal Articles
• Effects of Medical Therapies on Retinopathy Progression in Type 2 Diabetes  Journal Articles
• Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial  Journal Articles
• Effects of long term cholesterol lowering on coronary atherosclerosis in patient risk factor subgroups: the Simvastatin/enalapril Coronary Atherosclerosis Trial (SCAT).  Journal Articles
• Effects of routine early treatment with PCSK9 inhibitors in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: a randomised, double-blind, sham-controlled trial&nbsp;  Journal Articles
• Efficacy and Tolerability of Evolocumab vs Ezetimibe in Patients With Muscle-Related Statin Intolerance  Journal Articles
• Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174 000 participants in 27 randomised trials  Journal Articles
• Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins  Journal Articles
• Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials  Journal Articles
• Efficacy and safety of rosuvastatin therapy in children and adolescents with familial hypercholesterolemia: Results from the CHARON study  Journal Articles
• Efficacy and safety of ursodeoxycholic acid in primary, type IIa or IIb hypercholesterolemia: A multicenter, randomized, double-blind clinical trial  Journal Articles
• Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis  Journal Articles
• Elevated cholesteryl ester transfer protein (CETP) activity, a major determinant of the atherogenic dyslipidemia, and atherosclerotic cardiovascular disease in South Asians  Journal Articles
• Evaluation of a chronic disease management system for the treatment and management of diabetes in primary health care practices in Ontario: an observational study.  Journal Articles
• Evolocumab in HIV-Infected Patients With Dyslipidemia  Journal Articles
• Exercise intensity and insulin sensitivity: how low can you go?  Journal Articles
• Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction  Journal Articles
• Exploring patient demographic and clinical characteristics associated with lipid-lowering pharmacotherapy use in primary care  Journal Articles
• Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes  Journal Articles
• Ezetimibe in high-risk, previously treated statin patients: a systematic review and network meta-analysis of lipid efficacy  Journal Articles
• Familial hypercholesterolaemia: pilot study to identify children at risk.  Journal Articles
• Feedback GAP: pragmatic, cluster-randomized trial of goal setting and action plans to increase the effectiveness of audit and feedback interventions in primary care  Journal Articles
• Fine Mapping of the Insulin-Induced Gene 2 Identifies a Variant Associated With LDL Cholesterol and Total Apolipoprotein B Levels  Journal Articles
• Genetic Etiology of Isolated Low HDL Syndrome  Journal Articles
• Genetic Loci Associated With Plasma Concentration of Low-Density Lipoprotein Cholesterol, High-Density Lipoprotein Cholesterol, Triglycerides, Apolipoprotein A1, and Apolipoprotein B Among 6382 White Women in Genome-Wide Analysis With Replication  Journal Articles
• Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study  Journal Articles
• Genetically Determined Height and Coronary Artery Disease  Journal Articles
• HDL Cholesterol, LDL Cholesterol, and Triglycerides as Risk Factors for CKD: A Mendelian Randomization Study  Journal Articles
• Healthy Behavior, Risk Factor Control, and Survival in the COURAGE Trial  Journal Articles
• Heart Protection Study  Journal Articles
• Household income and LDL-C goal attainment in patients with diabetes and dyslipidemia in a Canadian dataset  Journal Articles
• Identifying gene–gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts  Journal Articles
• Impact of blood pressure lowering, cholesterol lowering and their combination in Asians and non-Asians in those without cardiovascular disease: an analysis of the HOPE 3 study  Journal Articles
• Individual lifetime benefit from low-dose colchicine in patients with chronic coronary artery disease  Conferences
• Insights and Perspectives on Dietary Modifications to Reduce the Risk of Cardiovascular Disease  Journal Articles
• Intensity of Lipid Lowering With Statins and Brachial Artery Vascular Endothelium Reactivity After Acute Coronary Syndromes (from the BRAVER Trial)  Journal Articles
• Intensity of and Adherence to Lipid‐Lowering Therapy as Predictors of Major Adverse Cardiovascular Outcomes in Patients With Coronary Heart Disease  Journal Articles
• Interpretation of the evidence for the efficacy and safety of statin therapy  Journal Articles
• Investigation into the relationship between cord blood adiponectin levels and aortic intima media thickness in healthy, term neonates  Journal Articles
• Is the superiority of apoB over non–HDL-C as a marker of cardiovascular risk in the INTERHEART study due to confounding by related variables?  Journal Articles
• Lack of Association of Ghrelin Precursor Gene Variants and Percentage Body Fat or Serum Lipid Profiles  Journal Articles
• Lack of Effect of Lowering LDL Cholesterol on Cancer: Meta-Analysis of Individual Data from 175,000 People in 27 Randomised Trials of Statin Therapy  Journal Articles
• Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci  Journal Articles
• Limitations of statin monotherapy for the treatment of dyslipidemia: a projection based on the Canadian lipid study – observational  Journal Articles
• Lipid Management in Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2013 Clinical Practice Guideline  Journal Articles
• Lipid Profile, Plasma Apolipoproteins, and Risk of a First Myocardial Infarction Among Asians  Journal Articles
• Lipid control and stroke risk in atrial fibrillation patients treated with direct oral anticoagulants and statins.  Journal Articles
• Lipid distributions in the Global Diagnostics Network across five continents  Journal Articles
• Lipid lowering for primary prevention  Journal Articles
• Lipid-lowering treatment intensity, persistence, adherence and goal attainment in patients with coronary heart disease  Journal Articles
• Lipoprotein(a) Cholesterol Masquerading as Low-Density Lipoprotein Cholesterol  Journal Articles
• Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol  Journal Articles
• Lipoproteins as mediators for the effects of alcohol consumption and cigarette smoking on cardiovascular mortality: results form the Lipid Research Clinics Follow-up Study.  Journal Articles
• Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis  Journal Articles
• Long-term Effects of Statins, Blood Pressure-Lowering, and Both on Erectile Function in Persons at Intermediate Risk for Cardiovascular Disease: A Substudy of the Heart Outcomes Prevention Evaluation-3 (HOPE-3) Randomized Controlled Trial  Journal Articles
• Low- and High-Volume of Intensive Endurance Training Significantly Improves Maximal Oxygen Uptake after 10-Weeks of Training in Healthy Men  Journal Articles
• Lower serum magnesium is associated with vascular calcification in peritoneal dialysis patients: a cross sectional study  Journal Articles
• MRC/BHF Heart Protection Study of cholesterol-lowering therapy and of antioxidant vitamin supplementation in a wide range of patients at increased risk of coronary heart disease death: early safety and efficacy experience  Journal Articles
• Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries  Journal Articles
• Meta-Analysis of Fructose and Cholesterol: A Concern Regarding Missing Data  Journal Articles
• Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report  Journal Articles
• Metformin in adults with type 1 diabetes: Design and methods of REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL): An international multicentre trial  Journal Articles
• Modulation of arterial reactivity using amlodipine and atorvastatin measured by ultrasound examination (MARGAUX)  Journal Articles
• Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy  Journal Articles
• Novel Approaches in Primary Cardiovascular Disease Prevention: The HOPE-3 Trial Rationale, Design, and Participants' Baseline Characteristics  Journal Articles
• Novel predictors of overt nephropathy in subjects with type 1 diabetes. A nested case control study from the Pittsburgh Epidemiology of Diabetes Complications cohort  Journal Articles
• Nuts as a Replacement for Carbohydrates in the Diabetic Diet  Journal Articles
• Nuts as a replacement for carbohydrates in the diabetic diet: a reanalysis of a randomised controlled trial  Journal Articles
• Overview of Therapeutic Approaches for Cholesterol Lowering and Attenuation of Thrombosis for Prevention of Atherothrombosis  Journal Articles
• Oxidative Stress and Lung Function  Journal Articles
• PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study  Journal Articles
• PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations  Journal Articles
• Paroxetine-induced increase in LDL cholesterol levels  Journal Articles
• Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9  Journal Articles
• Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study  Journal Articles
• Plasma Triglyceride Level and Mortality from Coronary Heart Disease  Journal Articles
• Polygenic Risk Score for Low-Density Lipoprotein Cholesterol Is Associated With Risk of Ischemic Heart Disease and Enriches for Individuals With Familial Hypercholesterolemia  Journal Articles
• Polypill with or without Aspirin in Persons without Cardiovascular Disease  Journal Articles
• Pooled RCTs: Lowering LDL-C levels using statins reduces major vascular events in all age groups  Journal Articles
• Prognostic factors of coronary heart disease in asymptomatic diabetics for inclusion on the kidney transplant waiting list. Screening with coronary angiography.  Journal Articles
• Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes  Journal Articles
• Race/Ethnic Differences in the Associations of the Framingham Risk Factors with Carotid IMT and Cardiovascular Events  Journal Articles
• Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions  Journal Articles
• Reaching recommended lipid and blood pressure targets with amlodipine/atorvastatin combination in patients with coronary heart disease  Journal Articles
• Relationship between remnant cholesterol and risk of heart failure in participants with diabetes mellitus  Journal Articles
• Relative effects of LDL-C on ischemic stroke and coronary disease  Journal Articles
• Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample  Journal Articles
• Results of a province-wide quality assurance program assessing the accuracy of cholesterol, triglycerides, and high-density lipoprotein cholesterol measurements and calculated low-density lipoprotein cholesterol in Ontario, using fresh human serum.  Journal Articles
• Risk Factor Control for Coronary Artery Disease Secondary Prevention in Large Randomized Trials  Journal Articles
• Role of Lipoprotein Apheresis in Cardiovascular Disease Risk Reduction  Journal Articles
• Safety of proprotein convertase subtilisin/kexin 9 inhibitors: a systematic review and meta-analysis  Journal Articles
• Safety of the PCSK9 inhibitor alirocumab: insights from 47 296 patient-years of observation.  Journal Articles
• Severe Obesity, Obesity, and Cardiometabolic Risk in Children 0 to 6 Years of Age  Journal Articles
• Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice  Journal Articles
• Statin Effects on LDL and HDL Cholesterol in South Asian and White Populations  Journal Articles
• Statin therapy in Canadian patients with hypercholesterolemia: the Canadian Lipid Study -- Observational (CALIPSO).  Journal Articles
• Study of Heart and Renal Protection (SHARP): Randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease  Journal Articles
• Systematic Review: Comparative Effectiveness and Harms of Combination Therapy and Monotherapy for Dyslipidemia  Journal Articles
• Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution  Journal Articles
• Targeting the Unstable Plaque in Acute Coronary Syndromes  Journal Articles
• The New Dyslipidemia Guidelines: What Is the Debate?  Journal Articles
• The effectiveness of hydroxychloroquine in patients with type 2 diabetes mellitus who are refractory to sulfonylureas—a randomized trial  Journal Articles
• The effects of inulin-type fructans on cardiovascular disease risk factors: systematic review and meta-analysis of randomized controlled trials  Journal Articles
• The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials  Journal Articles
• The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol  Journal Articles
• The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism  Journal Articles
• Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart  Journal Articles
• Vascular viewpoint  Journal Articles
• When is equal not equal?  Journal Articles
• Why is non−high-density lipoprotein cholesterol a better marker of the risk of vascular disease than low-density lipoprotein cholesterol?  Journal Articles