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Cardiovascular risk factors and non-invasive...
Journal article

Cardiovascular risk factors and non-invasive assessment of subclinical atherosclerosis in youth

Abstract

Our understanding of the natural history of atherosclerosis in childhood and its response to cardiovascular (CV) risk factor reduction have been hampered by the lack of a reliable, non-invasive measure of atherosclerosis. Carotid intima media thickness (IMT), a surrogate marker of atherosclerosis in adults, is increased in youth heterozygous for familial hypercholesterolemia (FH) and declines with lipid lowering pharmacotherapy. The age at …

Authors

Morrison KM; Dyal L; Conner W; Helden E; Newkirk L; Yusuf S; Lonn E

Journal

Atherosclerosis, Vol. 208, No. 2, pp. 501–505

Publisher

Elsevier

Publication Date

February 2010

DOI

10.1016/j.atherosclerosis.2009.07.034

ISSN

0021-9150