Journal article
Novel predictors of overt nephropathy in subjects with type 1 diabetes. A nested case control study from the Pittsburgh Epidemiology of Diabetes Complications cohort
Abstract
BACKGROUND: Predictors of diabetic nephropathy are only partly known and traditional risk factors do not adequately explain disease risk. We thus examined novel risk factors for overt nephropathy (ON) in type 1 diabetes.
METHODS: The EDC is a prospective study of childhood-onset type 1 diabetes. When first seen (1986-1988), mean age was 28 and diabetes duration 19 years. In the subsequent 10 years, 56 of 485 subjects without ON in 1986-88 …
Authors
Yishak AA; Costacou T; Virella G; Zgibor J; Fried L; Walsh M; Evans RW; Lopes-Virella M; Kagan VE; Otvos J
Journal
Nephrology Dialysis Transplantation, Vol. 21, No. 1, pp. 93–100
Publisher
Oxford University Press (OUP)
Publication Date
January 1, 2006
DOI
10.1093/ndt/gfi103
ISSN
0931-0509
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdultAge DistributionAntigen-Antibody ComplexBiomarkersBlood GlucoseCase-Control StudiesCholesterol, HDLCholesterol, LDLCohort StudiesComorbidityDiabetes Mellitus, Type 1Diabetic NephropathiesFemaleGlycated HemoglobinHumansKidney Function TestsMaleMultivariate AnalysisPredictive Value of TestsPrevalenceProbabilityPrognosisReference ValuesRisk AssessmentSeverity of Illness IndexSex Distribution