Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries Academic Article uri icon

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abstract

  • BACKGROUND AND AIMS: One of the objectives of the ESC-EORP EUROASPIRE V survey is to determine how well European guidelines on the management of dyslipidaemias are implemented in coronary patients. METHODS: Standardized methods were used by trained technicians to collect information on 7824 patients from 130 centers in 27 countries, from the medical records and at a visit at least 6 months after hospitalization for a coronary event. All lipid measurements were performed in one central laboratory. Patients were divided into three groups: on high-intensity LDL-C-lowering-drug therapy (LLT), on low or moderate-intensity LLT and on no LLT. RESULTS: At the time of the visit, almost half of the patients were on a high-intensity LLT. Between hospital discharge and the visit, LLT had been reduced in intensity or interrupted in 20.8% of the patients and had been started or increased in intensity in 11.7%. In those who had interrupted LLT or had reduced the intensity, intolerance to LLT and the advice of their physician were reported as the reason why in 15.8 and 36.8% of the cases, respectively. LDL-C control was better in those on a high-intensity LLT compared to those on low or moderate intensity LLT. LDL-C control was better in men than women and in patients with self-reported diabetes. CONCLUSIONS: The results of the EUROASPIRE V survey show that most coronary patients have a less than optimal management of LDL-C. More professional strategies are needed, aiming at lifestyle changes and LLT adapted to the need of the individual patient.

authors

  • De Backer, Guy
  • Jankowski, Piotr
  • Kotseva, Kornelia
  • Mirrakhimov, Erkin
  • Reiner, Željko
  • Rydén, Lars
  • Tokgözoğlu, Lale
  • Wood, David
  • De Bacquer, Dirk
  • De Backer, G
  • Jankowski, P
  • Kotseva, K
  • Mirrakhimov, E
  • Reiner, Z
  • Rydén, L
  • Tokgözoğlu, L
  • Wood, D
  • De Bacquer, D
  • Kotseva, K
  • De Backer, G
  • Abreu, A
  • Aguiar, C
  • Badariene, J
  • Bruthans, J
  • Castro Conde, A
  • Cifkova, R
  • Crowley, J
  • Davletov, K
  • Bacquer, D De
  • De Smedt, D
  • De Sutter, J
  • Deckers, JW
  • Dilic, M
  • Dolzhenko, M
  • Druais, H
  • Dzerve, V
  • Erglis, A
  • Fras, Z
  • Gaita, D
  • Gotcheva, N
  • Grobbee, DE
  • Gyberg, V
  • Hasan Ali, H
  • Heuschmann, P
  • Hoes, AW
  • Jankowski, P
  • Lalic, N
  • Lehto, S
  • Lovic, D
  • Maggioni, AP
  • Mancas, S
  • Marques-Vidal, P
  • Mellbin, L
  • Miličić, D
  • Mirrakhimov, E
  • Oganov, R
  • Pogosova, N
  • Reiner, Ž
  • Rydén, L
  • Stagmo, M
  • Störk, S
  • Sundvall, J
  • Tokgözoğlu, L
  • Tsioufis, K
  • Vulic, D
  • Wood, D
  • Wood, DA
  • Kotseva, K
  • Jennings, C
  • Adamska, A
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  • Rydén, L
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publication date

  • June 2019