Journal article
Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
Abstract
BACKGROUND: Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but whether the addition of ezetimibe, a nonstatin drug that reduces intestinal cholesterol absorption, can reduce the rate of cardiovascular events further is not known.
METHODS: We conducted a double-blind, randomized trial involving 18,144 patients who had been hospitalized for an acute coronary syndrome within the …
Authors
Cannon CP; Blazing MA; Giugliano RP; McCagg A; White JA; Theroux P; Darius H; Lewis BS; Ophuis TO; Jukema JW
Journal
The New England Journal of Medicine, Vol. 372, No. 25, pp. 2387–2397
Publisher
Massachusetts Medical Society
Publication Date
June 18, 2015
DOI
10.1056/nejmoa1410489
ISSN
0028-4793