Journal article
Effects of Lipid‐Lowering and Antihypertensive Treatments in Addition to Healthy Lifestyles in Primary Prevention: An Analysis of the HOPE‐3 Trial
Abstract
BACKGROUND: It is not clear whether the effects of lipid-lowering or antihypertensive medications are influenced by adherence to healthy lifestyle factors. We assessed the effects of both drug interventions in subgroups by the number of healthy lifestyle factors in participants in the HOPE-3 (Heart Outcomes Prevention Evaluation) trial.
METHODS AND RESULTS: In this primary prevention trial, 4 healthy lifestyle factors (nonsmoking status, …
Authors
Dagenais GR; Jung H; Lonn E; Bogaty PM; Dehghan M; Held C; Avezum A; Jansky P; Keltai M; Leiter LA
Journal
Journal of the American Heart Association, Vol. 7, No. 15,
Publisher
Wolters Kluwer
Publication Date
August 7, 2018
DOI
10.1161/jaha.118.008918
ISSN
2047-9980
Associated Experts
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
AgedAnticholesteremic AgentsAntihypertensive AgentsBenzimidazolesBiphenyl CompoundsCardiovascular DiseasesCholesterol, LDLDouble-Blind MethodDrug Therapy, CombinationFemaleHealthy LifestyleHumansHydrochlorothiazideMaleMiddle AgedPrimary PreventionRisk FactorsRosuvastatin CalciumTetrazolesTreatment Outcome