Chlorocebus aethiops Concept

subject area of

• 5-(Perylen-3-yl)Ethynyl-arabino-Uridine (aUY11), an Arabino-Based Rigid Amphipathic Fusion Inhibitor, Targets Virion Envelope Lipids To Inhibit Fusion of Influenza Virus, Hepatitis C Virus, and Other Enveloped Viruses  Academic Article
• A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus*  Academic Article
• A Single Amino Acid Substitution in Herpes Simplex Virus Type 1 VP16 Inhibits Binding to the Virion Host Shutoff Protein and Is Incompatible with Virus Growth  Academic Article
• A conserved MADS-box phosphorylation motif regulates differentiation and mitochondrial function in skeletal, cardiac, and smooth muscle cells  Academic Article
• A critical role for IL‐15 in TLR‐mediated innate antiviral immunity against genital HSV‐2 infection  Academic Article
• Activation of theWT1tumor suppressor gene promoter by Pea3  Academic Article
• Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis  Academic Article
• Amino acid substitutions of the P2 residue of human antithrombin that either enhance or impair function  Academic Article
• Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines  Academic Article
• Cell Fusion-Induced Activation of Interferon-Stimulated Genes Is Not Required for Restriction of a Herpes Simplex Virus VP16/ICP0 Mutant in Heterokarya Formed between Permissive and Restrictive Cells  Academic Article
• Cellular basis for the species differences in sensitivity to cardiac glycosides (digitalis)  Academic Article
• Changes in mitochondrial shape and distribution induced by ethacrynic acid and the transient formation of a mitochondrial reticulum  Academic Article
• Characterization of the interferon regulatory factor 3-mediated antiviral response in a cell line deficient for IFN production  Academic Article
• Cigarette smoke attenuation of poly I:C-induced innate antiviral responses in human PBMC is mainly due to inhibition of IFN-β production  Academic Article
• Comparison of three cell-based drug screening platforms for HSV-1 infection  Academic Article
• Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy  Academic Article
• Crosstalk between the thyroid hormone and peroxisome proliferator-activated receptors in regulating peroxisome proliferator-responsive genes  Academic Article
• Determination of the Topology of the Hydrophobic Segment of Mammalian Diacylglycerol Kinase Epsilon in a Cell Membrane and Its Relationship to Predictions from Modeling  Academic Article
• Diacylglycerol Kinase ϵ Is Selective for Both Acyl Chains of Phosphatidic Acid or Diacylglycerol  Academic Article
• Differential Modification of Interferon Regulatory Factor 3 following Virus Particle Entry  Academic Article
• Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS  Academic Article
• Discovery of potent antiviral (HSV-1) quinazolinones and initial structure-activity relationship studies  Academic Article
• Distinct Properties of the Two Isoforms of CDP-Diacylglycerol Synthase  Academic Article
• Effects of deletions in the carboxy-terminal hydrophobic region of herpes simplex virus glycoprotein gB on intracellular transport and membrane anchoring.  Academic Article
• Epitope discovery in West Nile virus infection: Identification and immune recognition of viral epitopes  Academic Article
• Evidence that Herpes Simplex Virus VP16 Is Required for Viral Egress Downstream of the Initial Envelopment Event  Academic Article
• Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity  Academic Article
• Functional inaccessibility of quiescent herpes simplex virus genomes.  Academic Article
• Glycoproteins E and I facilitate neuron-to-neuron spread of herpes simplex virus.  Academic Article
• Glycoproteins of herpes simplex virus type 2 as defined by monoclonal antibodies.  Academic Article
• Harnessing Oncolytic Virus-mediated Antitumor Immunity in an Infected Cell Vaccine  Academic Article
• Heparin cofactor II is more sensitive than antithrombin to secretory impairment arising from mutations introduced into its carboxy-terminal region  Academic Article
• Herpes Simplex Virus ICP0 Mutants Are Hypersensitive to Interferon  Academic Article
• Herpes Simplex Virus ICP0 and ICP34.5 Counteract Distinct Interferon-Induced Barriers to Virus Replication  Academic Article
• Herpes Simplex Virus gD and Virions Accumulate in Endosomes by Mannose 6-Phosphate-Dependent and -Independent Mechanisms  Academic Article
• Herpes simplex virus VP16 rescues viral mRNA from destruction by the virion host shutoff function.  Academic Article
• Ibuprofen Induces Mitochondrial-Mediated Apoptosis Through Proteasomal Dysfunction  Academic Article
• Identification of a Domain (155–183) on CD36 Implicated in the Phagocytosis of Apoptotic Neutrophils  Academic Article
• Identification of a Novel Pathway Essential for the Immediate-Early, Interferon-Independent Antiviral Response to Enveloped Virions  Academic Article
• Identification of a hTid-1 mutation which sensitizes gliomas to apoptosis  Academic Article
• Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2.  Academic Article
• Immunization with adenovirus at the large intestinal mucosa as an effective vaccination strategy against sexually transmitted viral infection  Academic Article
• Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin  Academic Article
• Innate Cellular Response to Virus Particle Entry Requires IRF3 but Not Virus Replication  Academic Article
• Intracellular events determine the fate of antithrombin Utah  Academic Article
• Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases  Academic Article
• Large Changes in the CRAC Segment of gp41 of HIV Do Not Destroy Fusion Activity if the Segment Interacts with Cholesterol†  Academic Article
• Lipid Modulation of the Activity of Diacylglycerol Kinase α- and ζ-Isoforms:  Activation by Phosphatidylethanolamine and Cholesterol†  Academic Article
• Location of the multimerin 1 binding site in coagulation factor V: An update  Academic Article
• Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model  Academic Article
• Mechanical stretch-induced RhoA activation is mediated by the RhoGEF Vav2 in mesangial cells  Academic Article
• Membrane Perturbation Elicits an IRF3-Dependent, Interferon-Independent Antiviral Response  Academic Article
• Mitochondrial import of human and yeast fumarase in live mammalian cells: Retrograde translocation of the yeast enzyme is mainly caused by its poor targeting sequence  Academic Article
• Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms  Academic Article
• Myristoylation, a Protruding Loop, and Structural Plasticity Are Essential Features of a Nonenveloped Virus Fusion Peptide Motif  Academic Article
• Partial characterization of the genome of nine animal caliciviruses  Academic Article
• Partial purification and characterization of the ribonucleotide reductase induced by herpes simplex virus infection of mammalian cells.  Academic Article
• Phosphatidylinositol-4-phosphate 5-Kinase Isoforms Exhibit Acyl Chain Selectivity for Both Substrate and Lipid Activator  Academic Article
• Phylogenetic analysis of the diacylglycerol kinase family of proteins and identification of multiple highly-specific conserved inserts and deletions within the catalytic domain that are distinctive characteristics of different classes of DGK homologs  Academic Article
• Pre-surgical neoadjuvant oncolytic virotherapy confers protection against rechallenge in a murine model of breast cancer  Academic Article
• Programmable insect cell carriers for systemic delivery of integrated cancer biotherapy  Academic Article
• Proinflammatory Cytokines and Chemokines - But not Interferon-β - Produced in Response to HSV-2 in Primary Human Genital Epithelial Cells are Associated with Viral Replication and the Presence of the Virion Host Shutoff Protein  Academic Article
• Proteolytic Cleavage of Ataxin-7 by Caspase-7 Modulates Cellular Toxicity and Transcriptional Dysregulation  Academic Article
• R-spondin1 Is a High Affinity Ligand for LRP6 and Induces LRP6 Phosphorylation and β-Catenin Signaling  Academic Article
• R430: A potent inhibitor of DNA and RNA viruses  Academic Article
• RELATIONSHIP OF MELANOMA-ASSOCIATED ANTIGENS TO HISTOCOMPATIBILITY ANTIGEN AND β-2 MICROGLOBULIN IN MATERIAL SPONTANEOUSLY SHED BY CULTURED HUMAN MELANOMA CELLS  Academic Article
• Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity  Academic Article
• Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.  Academic Article
• Role of the Hydrophobic Segment of Diacylglycerol Kinase ε†  Academic Article
• Role of the viral and cellular encoded thymidine kinase in the repair of UV-irradiated herpes simplex virus  Academic Article
• Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis  Academic Article
• Sequence-dependent DNA replication in preimplantation mouse embryos.  Academic Article
• Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling  Academic Article
• Stabilization of HSV-2 viral vaccine candidate by spray drying  Academic Article
• Study of Arachidonoyl Specificity in Two Enzymes of the PI Cycle  Academic Article
• Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing  Academic Article
• The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatus  Academic Article
• The Transactivation Function of the Pea3 Subfamily Ets Transcription Factors Is Regulated by Sumoylation  Academic Article
• The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs  Academic Article
• The pea3 subfamily ets genes are required for HER2/Neu-mediated mammary oncogenesis  Academic Article
• The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines.  Academic Article
• Thermal Stabilization of Viral Vaccines in Low-Cost Sugar Films  Academic Article
• Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes  Academic Article
• Translocation of verotoxin-1 across T84 monolayers: mechanism of bacterial toxin penetration of epithelium  Academic Article
• Truncation of the C-Terminal Acidic Transcriptional Activation Domain of Herpes Simplex Virus VP16 Renders Expression of the Immediate-Early Genes Almost Entirely Dependent on ICP0  Academic Article
• UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways  Academic Article
• Using G-deleted vesicular stomatitis virus to probe the innate anti-viral response  Academic Article
• Variants of theorexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity  Academic Article
• Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?  Academic Article
• Widely Used Herpes Simplex Virus 1 ICP0 Deletion Mutant Strain dl1403 and Its Derivative Viruses Do Not Express Glycoprotein C Due to a Secondary Mutation in the gC Gene  Academic Article
• ets‐1 is transcriptionally up‐regulated by H 2 O 2 via an antioxidant response element  Academic Article
• p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade  Academic Article