Journal article
Sequence-Dependent DNA Replication in Preimplantation Mouse Embryos
Abstract
Circular, double-stranded DNA molecules were injected into nuclei of mouse oocytes and one- or two-cell embryos to determine whether specific sequences were required to replicate DNA during mouse development. Although all of the injected DNAs were stable, replication of plasmid pML-1 DNA was not detected unless it contained either polyomavirus (PyV) or simian virus 40 (SV40) DNA sequences. Replication occurred in embryos, but not in oocytes. …
Authors
Wirak DO; Chalifour LE; Wassarman PM; Muller WJ; Hassell JA; DePamphilis ML
Journal
Molecular and Cellular Biology, Vol. 5, No. 11, pp. 2924–2935
Publisher
Taylor & Francis
Publication Date
November 1, 1985
DOI
10.1128/mcb.5.11.2924-2935.1985
ISSN
0270-7306