Calcium Channel Blockers Concept

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• 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives (Part 1): Action in Ion Channels and GPCRs  Journal Articles
• A 26-week, prospective, open-label, uncontrolled, multicenter study to evaluate the effect of an escalating-dose regimen of trandolapril on change in blood pressure in treatment-naive and concurrently treated adult hypertensive subjects (TRAIL)  Journal Articles
• A Survey of Canadian Practitioners Regarding the Management of the Hypertensive Disorders of Pregnancy  Journal Articles
• A new view of K+-induced contraction in rat aorta: the role of Ca2+ binding  Journal Articles
• ATP-dependent Ca-uptake by rat vas deferens smooth muscle microsomes: properties of oxalate stimulated and oxalate-independent Ca-uptake.  Journal Articles
• Adjunctive therapy for myocardial infarction.  Journal Articles
• Agonist-induced contractile responses of human bronchial muscle in vitro: Effects of Ca2+ removal, La3+ and PY108068  Journal Articles
• An Oral Calcium Antagonist for Treatment of Hypertensive Emergencies  Journal Articles
• Antihypertensive Drug Prescribing and Persistence Among New Elderly Users: Implications for Persistence Improvement Interventions  Journal Articles
• Antihypertensive Treatment Using Calcium Antagonists in Combination with Captopril Rather than Diuretics  Journal Articles
• Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis  Journal Articles
• Beta-blockers and cardiovascular outcomes in dialysis patients: a cohort study in Ontario, Canada  Journal Articles
• Beyond the year 2000 in CHD research: current understanding of the cellular mechanism of atherosclerosis.  Journal Articles
• Bilateral blindness secondary to optic nerve ischemia from severe amlodipine overdose: a case report  Journal Articles
• Blocking T-type calcium channels with tetrandrine inhibits steroidogenesis in bovine adrenal glomerulosa cells  Journal Articles
• Blood Pressure Lowering With Nilvadipine in Patients With Mild‐to‐Moderate Alzheimer Disease Does Not Increase the Prevalence of Orthostatic Hypotension  Journal Articles
• Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis  Journal Articles
• Ca²⁺ channel ligand activities in uterine smooth muscle: influence of hormonal status  Journal Articles
• Calcinosis is associated with digital ischaemia in systemic sclerosis—a longitudinal study  Journal Articles
• Calcium Antagonists in Coronary Artery Disease and Hypertension  Journal Articles
• Calcium Channel Blocker–Clarithromycin Drug Interaction Did Not Increase the Risk of Nonvertebral Fracture  Journal Articles
• Calcium antagonistic actions of tetrandrine depend on cell types.  Journal Articles
• Calcium antagonists and acute renal failure  Journal Articles
• Calcium antagonists in coronary disease and hypertension.  Journal Articles
• Calcium antagonists in the treatment of ischemic heart disease  Journal Articles
• Calcium channel antagonist binding and pharmacology in rat uterine smooth muscle  Journal Articles
• Calcium channel blockers in acute myocardial infarction and unstable angina: an overview.  Journal Articles
• Calcium-Channel Blocker–Clarithromycin Drug Interactions and Acute Kidney Injury  Journal Articles
• Calcium-channel antagonist binding to isolated vascular smooth muscle membranes  Journal Articles
• Calcium-stimulated short-circuit currents in the canine proximal colonic epithelium: effects of DK-PGD₂, a metabolite of prostaglandin D₂  Journal Articles
• Canadian Cardiovascular Society Guidelines for the Diagnosis and Management of Stable Ischemic Heart Disease  Journal Articles
• Capacitative Ca2+ entry in HL-60 cells: tetrandrine and SK & F 96365 as probes.  Journal Articles
• Caveolae from canine airway smooth muscle contain the necessary components for a role in Ca²⁺handling  Journal Articles
• Changes in acute myocardial infarction risk and patterns of practice for patients older and younger than 70 years, 1987-90.  Journal Articles
• Changes in free-calcium levels and pH in synaptosomes during transmitter release  Journal Articles
• Characterization and solubilization of the nitrendipine binding protein from canine small intestinal circular smooth muscle  Journal Articles
• Chronic Nicotine Blunts Hypoxic Sensitivity in Perinatal Rat Adrenal Chromaffin Cells via Upregulation of K_ATPChannels: Role of α7 Nicotinic Acetylcholine Receptor and Hypoxia-Inducible Factor-2α  Journal Articles
• Cl⁻ transport by cystic fibrosis transmembrane conductance regulator (CFTR) contributes to the inhibition of epithelial Na⁺ channels (ENaCs) in Xenopus oocytes co‐expressing CFTR and ENaC  Journal Articles
• Clinical features and contemporary management of patients with low and preserved ejection fraction heart failure: baseline characteristics of patients in the Candesartan in Heart failure—Assessment of Reduction in Mortality and morbidity (CHARM) programme  Journal Articles
• Cobra venom cardiotoxin induces aggregation of washed rat platelets: dual effects of Ca2+.  Journal Articles
• Comparison of lowest energy conformations of dimethylcurine and methoxyverapamil: Evidence of ternary association of calcium channel, Ca2+, and calcium entry blockers  Journal Articles
• Contraction‐induced muscle damage in humans following calcium channel blocker administration  Journal Articles
• Cooperation in signal transduction of extracellular guanosine 5′ triphosphate and nerve growth factor in neuronal differentiation of PC12 cells  Journal Articles
• Coronary vasospasm: a case report and review of the literature.  Journal Articles
• Current Perspectives in the Pharmacological Studies of Store-Operated Ca2+ Entry Blockers.  Journal Articles
• Current and ongoing randomized trials in heart failure and left ventricular dysfunction  Journal Articles
• Current status of safety and efficacy of calcium channel blockers in cardiovascular diseases: A critical analysis based on 100 studies  Journal Articles
• Cyclopiazonic acid, inhibiting the endoplasmic reticulum calcium pump, reduces the canine colonic pacemaker frequency.  Journal Articles
• Decreasing Mortality With Primary Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction: The Mayo Clinic Experience From 1991 Through 1997  Conferences
• Determinants of health-related quality of life in women with vertebral fractures  Journal Articles
• Development of pacemaker activity and interstitial cells of cajal in the neonatal mouse small intestine  Journal Articles
• Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine  Journal Articles
• Dopaminergic Properties of Cultured Rat Carotid Body Chemoreceptors Grown in Normoxic and Hypoxic Environments  Journal Articles
• Dual effect of cobra cardiotoxin on vascular smooth muscle and endothelium.  Journal Articles
• Dual effects of SK&F 96365 in human leukemic HL-60 cells  Journal Articles
• Dual effects of tetrandrine on cytosolic calcium in human leukaemic HL‐60 cells: intracellular calcium release and calcium entry blockade  Journal Articles
• EFFECTS OF TETRANDRINE AND CLOSELY RELATED BIS‐BENZYLISOQUINOLINE DERIVATIVES ON CYTOSOLIC Ca²⁺ IN HUMAN LEUKAEMIC HL‐60 CELLS: A STRUCTURE‐ACTIVITY RELATIONSHIP STUDY  Journal Articles
• Effect of PCI on Quality of Life in Patients with Stable Coronary Disease  Journal Articles
• Effect of calcium on the vascular contraction induced by cobra venom cardiotoxin  Journal Articles
• Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials  Journal Articles
• Effects of TMB-8, a calcium antagonist, on transport properties of the isolated canine tracheal epithelium  Journal Articles
• Effects of calcium antagonists on the risks of coronary heart disease, cancer and bleeding  Journal Articles
• Effects of calcium antagonists on the risks of coronary heart disease, cancer and bleeding. Ad Hoc Subcommittee of the Liaison Committee of the World Health Organisation and the International Society of Hypertension.  Journal Articles
• Effects of calcium channel blockers on survival after myocardial infarction  Journal Articles
• Effects of chemostimuli on [Ca²⁺]_i responses of rat aortic body type I cells and endogenous local neurons: comparison with carotid body cells  Journal Articles
• Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials  Journal Articles
• Effects of isometric handgrip training among people medicated for hypertension: a multilevel analysis  Journal Articles
• Effects of  -blockers and calcium channel blockers in acute myocardial infarction  Journal Articles
• Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction  Journal Articles
• Endothelium-independent vasorelaxation by leonurine, a plant alkaloid purified from Chinese motherwort  Journal Articles
• Evidence for P2-purinoceptors contribution in H2O2-induced contraction of rat aorta in the absence of endothelium  Journal Articles
• Evidence for two types of internal Ca2+ stores in canine mesenteric artery with different refilling mechanisms  Journal Articles
• Excitation‐contraction coupling and uncoupling in airway smooth muscle.  Journal Articles
• Exposing Patients With Chronic, Stable, Exertional Angina to Placebo Periods in Drug Trials  Journal Articles
• Extended-release nifedipine and the risk of intestinal obstruction: a population-based study  Journal Articles
• Extracellular guanosine 5′ triphosphate enhances nerve growth factor-induced neurite outgrowth via increases in intracellular calcium  Journal Articles
• First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors  Journal Articles
• Generation of slow wave type action potentials in the mouse small intestine involves a non-L-type calcium channel  Journal Articles
• Ginger attenuates acetylcholine-induced contraction and Ca²⁺ signalling in murine airway smooth muscle cells  Journal Articles
• Green tea catechins evoke a phasic contraction in rat aorta via H₂O₂‐mediated multiple‐signalling pathways  Journal Articles
• Heart failure.  Journal Articles
• Heart failure.  Journal Articles
• Heart failure.  Journal Articles
• Heart failure.  Journal Articles
• How to manage hypertension in pregnancy effectively  Journal Articles
• Hydrochlorothiazide use and risk of keratinocyte carcinoma and melanoma: A multisite population-based cohort study  Journal Articles
• Identifying subpopulations for subgroup analysis in a longitudinal clinical trial  Journal Articles
• Impact of an Initial Strategy of Medical Therapy Without Percutaneous Coronary Intervention in High-Risk Patients From the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) Trial  Journal Articles
• Implications of Diabetes in Patients With Acute Coronary Syndromes<subtitle>The Global Registry of Acute Coronary Events</subtitle>  Journal Articles
• In vitro vasodilator mechanisms of the indole alkaloids rhynchophylline and isorhynchophylline, isolated from the hook of Uncaria rhynchophylla (Miquel)  Journal Articles
• Influence of nitric oxide and vasoactive intestinal peptide on the spontaneous and triggered electrical and mechanical activities of the canine ileum  Journal Articles
• Inhibition of endothelium-dependent vascular relaxation by tetrandrine  Journal Articles
• Inhibitory effects of tetrandrine and hernandezine on Ca2+ mobilization in rat glioma C6 cells.  Journal Articles
• Interactions of chloroethylclonidine with rauwolscine‐ and prazosin‐sensitive adrenoceptors in dog saphenous vein  Journal Articles
• Interventions that potentially limit myocardial infarct size: Overview of clinical trials  Journal Articles
• Is there an optimal combination of antihypertensives for preventing cardiovascular events?  Journal Articles
• Key Roles of Phe¹¹¹²and Ser¹¹¹⁵in the Pore-Forming IIIS5-S6 Linker of L-Type Ca²⁺Channel α_1CSubunit (Ca_V1.2) in Binding of Dihydropyridines and Action of Ca²⁺Channel Agonists  Journal Articles
• L-type Ca2+ channels, Ca2+-induced Ca2+ release, and BKCa channels in airway stretch-induced contraction  Journal Articles
• Left main coronary artery spasm: medical versus surgical management.  Journal Articles
• Ligand action on sodium, potassium, and calcium channels: role of permeant ions  Journal Articles
• Ligands of Diltiazem Binding Site: An Overview of Some Chemotypes  Journal Articles
• Low glucose sensitivity and polymodal chemosensing in neonatal rat adrenomedullary chromaffin cells  Journal Articles
• Management and Outcomes of Non-ST Elevation Acute Coronary Syndromes in Relation to Previous Use of Antianginal Therapies (from the Canadian Global Registry of Acute Coronary Events [GRACE] and Canadian Registry of Acute Coronary Events [CANRACE])  Journal Articles
• Mapping of dihydropyridine binding residues in a less sensitive invertebrate L-type calcium channel (LCa_v1)  Journal Articles
• Membrane currents in canine bronchial artery and their regulation by excitatory agonists  Journal Articles
• Mode of action of calcium antagonists on responses to spasmogens and antigen challenge in human airway smooth muscle  Journal Articles
• Modulation of arterial reactivity using amlodipine and atorvastatin measured by ultrasound examination (MARGAUX)  Journal Articles
• Myogenic electrical control activity in longitudinal muscle of human and dog colon.  Journal Articles
• N-Type Ca(2+) channels trigger release of excitatory and inhibitory neurotransmitter from nerve endings in canine bronchi.  Journal Articles
• Neurohormones and oxidative stress in nonischemic cardiomyopathy: relationship to survival and the effect of treatment with amlodipine  Journal Articles
• Nifedipine induces apoptosis in cultured vascular smooth muscle cells from spontaneously hypertensive rats  Journal Articles
• Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial  Journal Articles
• Non-chemotherapeutic agents that potentiate chemotherapy efficacy  Journal Articles
• On the origin of rhythmic calcium transients in the ICC-MP of the mouse small intestine  Journal Articles
• Optimization of controlled release nanoparticle formulation of verapamil hydrochloride using artificial neural networks with genetic algorithm and response surface methodology  Journal Articles
• Overview of pharmacological interventions after traumatic brain injuries: impact on selected outcomes  Journal Articles
• Overview of results of randomized clinical trials in heart disease. I. Treatments following myocardial infarction  Journal Articles
• PROTECT (Prospective Reinfarction Outcomes in the Thrombolytic Era Cardizem CD Trial): a randomized, double-blind clinical trial of diltiazem versus atenolol in secondary prophylaxis post non-Q wave myocardial infarction.  Journal Articles
• Patterns of Medication Use in Patients With Heart Failure  Journal Articles
• Pharmacokinetic and pharmacodynamic interactions between nisoldipine and propranolol  Journal Articles
• Pharmacological treatment for myocardial infarction Part 2: Implications of clinical trials of other adjunctive therapies.  Journal Articles
• Phenylalkylamines in calcium channels: computational analysis of experimental structures  Journal Articles
• Physicians' recommendations for patients who undergo noncardiac surgery.  Journal Articles
• Pinaverium acts as L-type calcium channel blocker on smooth muscle of colon  Journal Articles
• Plant alkaloids, tetrandrine and hernandezine, inhibit calcium-depletion stimulated calcium entry in human and bovine endothelial cells  Journal Articles
• Platelet derived growth factor-evoked Ca2+ wave and matrix gene expression through phospholipase C in human pulmonary fibroblast  Journal Articles
• Pregabalin and heart failure: A population‐based study  Journal Articles
• Primary and secondary prevention of myocardial infarction and strokes  Journal Articles
• Prophylactic Magnesium Sulfate for Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis  Journal Articles
• Randomised controlled double-blind trial of the calcium channel antagonist amlodipine in the treatment of acute alcoholic hepatitis  Journal Articles
• Relationship Between Changes in Bone Mineral Density and Vertebral Fracture Risk Associated With Risedronate  Journal Articles
• Relationship between calcium channel blockers and skin fibrosis in patients with systemic sclerosis.  Journal Articles
• Risk of Hospitalization for Community Acquired Pneumonia with Renin-Angiotensin Blockade in Elderly Patients: A Population-Based Study  Journal Articles
• Role of calcium in the control of steroidogenesis in preovulatory ovarian follicles of the goldfish  Journal Articles
• Role of nitric oxide-related inhibition in intestinal function: relation to vasoactive intestinal polypeptide  Journal Articles
• Routine medical management of acute myocardial infarction. Lessons from overviews of recent randomized controlled trials.  Journal Articles
• Selective Inhibition of Inward Rectifier K ⁺ Channels (Kir2.1 or Kir2.2) Abolishes Protection by Ischemic Preconditioning in Rabbit Ventricular Cardiomyocytes  Journal Articles
• Skeletal muscle contractile function predicts activity and behaviour in zebrafish  Journal Articles
• Specific interaction between tetrandrine and Quillaja saponins in promoting permeabilization of plasma membrane in human leukemic HL-60 cells  Journal Articles
• Structural Model for Phenylalkylamine Binding to L-type Calcium Channels  Journal Articles
• Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand  Journal Articles
• Subcellular distribution of [3H]nitrendipine binding in smooth muscle.  Journal Articles
• TETRANDRINE AS A CALCIUM ANTAGONIST  Journal Articles
• Tetrandrine and related bis-benzylisoquinoline alkaloids from medicinal herbs: cardiovascular effects and mechanisms of action.  Journal Articles
• Tetrandrine inhibits Ca2+ release-activated Ca2+ channels in vascular endothelial cells  Journal Articles
• Tetrandrine inhibits electrically induced [Ca2+]i transient in the isolated single rat cardiomyocyte  Journal Articles
• Tetrandrine is not a selective calcium channel blocker in vascular smooth muscle.  Journal Articles
• Tetrandrine, a calcium antagonist of Chinese herbal origin, interacts with vascular muscle α1-adrenoceptor  Journal Articles
• Tetrandrine: a vasodilator of medicinal herb origin with a novel contractile effect on dog saphenous vein  Journal Articles
• The Effects of Extracellular Calcium-Sensing Receptor Ligands on the Contractility of Pregnant Human Myometrium In Vitro  Journal Articles
• The Efficacy and Tolerability of Risedronate Once a week for the Treatment of Postmenopausal Osteoporosis  Journal Articles
• The Organization to Assess Strategies for Ischemic Syndromes (OASIS) registry in patients with unstable angina  Journal Articles
• The Treatment of Heart Failure  Journal Articles
• The Use of Beta-adrenergic Blocking Agents, IV Nitrates and Calcium Channel Blocking Agents following Acute Myocardial Infarction  Journal Articles
• The myogenic component in distention-induced peristalsis in the guinea pig small intestine  Journal Articles
• Two decades of progress in preventing vascular disease  Journal Articles
• Understanding Antihypertensive Medication Use after Living Kidney Donation through Linked National Registry and Pharmacy Claims Data  Journal Articles
• Update of effects of calcium antagonists in myocardial infarction or angina in light of the second danish verapamil infarction trial (DAVIT-II) and other recent studies  Journal Articles
• Verapamil following uncomplicated myocardial infarction: Promising, but not proven  Journal Articles
• [Protection of the ischemic myocardium].  Journal Articles
• α-channel and calcium-channel blockers are ineffective as medical expulsive therapy for ureteral stones regardless of size and location  Journal Articles