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Relationship Between Changes in Bone Mineral...
Journal article

Relationship Between Changes in Bone Mineral Density and Vertebral Fracture Risk Associated With Risedronate Greater Increases in Bone Mineral Density Do Not Relate to Greater Decreases in Fracture Risk

Abstract

Low bone mineral density (BMD) is correlated with increased fracture risk. Whether greater BMD increases induced by osteoporosis drugs are related to greater decreases in fracture risk is controversial. We analyzed the relationship between BMD change and fracture risk in postmenopausal osteoporotic women receiving antiresorptive treatment. The analysis combined data from three pivotal risedronate fracture end-point trials. Women received …

Authors

Watts NB; Cooper C; Lindsay R; Eastell R; Manhart MD; Barton IP; van Staa T-P; Adachi JD

Journal

Journal of Clinical Densitometry, Vol. 7, No. 3, pp. 255–261

Publisher

Elsevier

Publication Date

2004

DOI

10.1385/jcd:7:3:255

ISSN

1094-6950