Journal article
Identifying subpopulations for subgroup analysis in a longitudinal clinical trial
Abstract
BACKGROUND: In a typical clinical trial treatment effects will not be expected to be the same on all of the study participants. As a result, investigators are often tempted to look at the effects of a given treatment in subgroups of patients in order to determine who will benefit the most or the least, especially when the treatment effect in the total sample is insignificant or borderline. This paper aims at demonstrating the application of …
Authors
Moineddin R; Butt DA; Tomlinson G; Beyene J
Journal
Contemporary Clinical Trials, Vol. 29, No. 6, pp. 817–822
Publisher
Elsevier
Publication Date
November 2008
DOI
10.1016/j.cct.2008.07.002
ISSN
1551-7144