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TETRANDRINE AS A CALCIUM ANTAGONIST
Journal article

TETRANDRINE AS A CALCIUM ANTAGONIST

Abstract

1. The Ca(2+)-antagonism of tetrandrine (TET) on the Ca2+ mobilization in various types of cells were reviewed. Inositol trisphosphate (IP3)-generating drugs were used as Ca(2+)-mobilizing agonists and the effects were compared with those produced by using the microsomal Ca(2+)-ATPase inhibitor thapsigargin (TG), which is a tool for analysing Ca2+ store-regulated Ca2+ entry (capacitative Ca2+ entry). 2. In rat phaeochromocytoma PC12 cells, 100 …

Authors

Takemura H; Imoto K; Ohshika H; Kwan C

Journal

Clinical and Experimental Pharmacology and Physiology, Vol. 23, No. 8, pp. 751–753

Publisher

Wiley

Publication Date

August 1996

DOI

10.1111/j.1440-1681.1996.tb01772.x

ISSN

0305-1870