selected scholarly activity
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academic article
- Microbe and host interaction in gastrointestinal homeostasis. Psychopharmacology. 236:1623-1640. 2019
- Genome-wide association studies of placebo and duloxetine response in major depressive disorder. Pharmacogenomics Journal. 18:406-412. 2018
- Effects of exercise and enrichment on behaviour in CD-1 mice. Behavioural Brain Research. 342:43-50. 2018
- GWAS-based machine learning approach to predict duloxetine response in major depressive disorder. Journal of Psychiatric Research. 99:62-68. 2018
- The comparative effectiveness of electroencephalographic indices in predicting response to escitalopram therapy in depression: A pilot study. Journal of Affective Disorders. 227:542-549. 2018
- Stress & the gut-brain axis: Regulation by the microbiome. Neurobiology of Stress. 7:124-136. 2017
- Targeting the Microbiome for Mental Health: Hype or Hope?. Biological Psychiatry. 82:456-457. 2017
- Investigation of miR-1202, miR-135a, and miR-16 in Major Depressive Disorder and Antidepressant Response. International Journal of Neuropsychopharmacology. 20:619-623. 2017
- MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes. Nature Communications. 8:15497. 2017
- The 5-HTTLPR and BDNF polymorphisms moderate the association between uncinate fasciculus connectivity and antidepressants treatment response in major depression. European Archives of Psychiatry and Clinical Neuroscience. 267:135-147. 2017
- Gut Microbiota, Bacterial Translocation, and Interactions with Diet: Pathophysiological Links between Major Depressive Disorder and Non-Communicable Medical Comorbidities. Psychotherapy and Psychosomatics. 86:31-46. 2017
- Lactobacillus rhamnosus strain JB-1 reverses restraint stress-induced gut dysmotility. Neurogastroenterology and Motility. 29:e12903-e12903. 2017
- Discovering biomarkers for antidepressant response: protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical characteristics of the first patient cohort. BMC Psychiatry. 16:105. 2016
- The influence of 5-HTTLPR and Val66Met polymorphisms on cortical thickness and volume in limbic and paralimbic regions in depression: a preliminary study. BMC Psychiatry. 16:61. 2016
- White matter integrity in major depressive disorder: Implications of childhood trauma, 5-HTTLPR and BDNF polymorphisms. Psychiatry Research - Neuroimaging. 253:15-25. 2016
- White matter integrity in major depressive disorder: Implications of childhood trauma, 5-HTTLPR and BDNF polymorphisms. Psychiatry Research - Neuroimaging. 253:15-25. 2016
- Gut Microbiota and Brain Function: An Evolving Field in Neuroscience: Table 1.. International Journal of Neuropsychopharmacology. 19:pyv114-pyv114. 2016
- Amygdala responses to quetiapine XR and citalopram treatment in major depression: the role of 5-HTTLPR-S/Lg polymorphisms. Human Psychopharmacology. 31:144-155. 2016
- Developmental expression of the neuroligins and neurexins in fragile X mice. Journal of Comparative Neurology. 524:807-828. 2016
- Regional brain volumes changes in adult male FMR1-KO mouse on the FVB strain. Neuroscience. 318:12-21. 2016
- Structural & functional consequences of chronic psychosocial stress on the microbiome & host. Psychoneuroendocrinology. 63:217-227. 2016
- Zebrafish models of major depressive disorders. Journal of Neuroscience Research. 94:3-14. 2016
- Genetic variation inIL-1β, IL-2, IL-6, TSPOandBDNFand response to duloxetine or placebo treatment in major depressive disorder. Pharmacogenomics. 16:1919-1929. 2015
- Loss of T cells influences sex differences in behavior and brain structure. Brain, Behavior, and Immunity. 46:249-260. 2015
- Gut brain axis: diet microbiota interactions and implications for modulation of anxiety and depression. Current Opinion in Biotechnology. 32:35-41. 2015
- 3D visualization of the regional differences. Molecular Psychiatry. 20:1-1. 2015
- Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity. Molecular Psychiatry. 20:118-125. 2015
- Nucleus accumbens core and pathogenesis of compulsive checking. Behavioural Pharmacology. 26:200-216. 2015
- Psychobiotics and the gut–brain axis: in the pursuit of happiness. Neuropsychiatric Disease and Treatment. 11:715-715. 2015
- Performance of compulsive behavior in rats is not a unitary phenomenon - validation of separate functional components in compulsive checking behavior. European Journal of Neuroscience. 40:2971-2979. 2014
- Regional upregulation of hippocampal melatonin MT2 receptors by valproic acid: Therapeutic implications for Alzheimer's disease. Neuroscience Letters. 576:84-87. 2014
- Temporal and spectral differences in the ultrasonic vocalizations of fragile X knock out mice during postnatal development. Behavioural Brain Research. 259:119-130. 2014
- Gut–brain axis: how the microbiome influences anxiety and depression. Trends in Neurosciences. 36:305-312. 2013
- In utero exposure to valproic acid and autism — A current review of clinical and animal studies. Neurotoxicology and Teratology. 36:47-56. 2013
- The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse. Neurogastroenterology and Motility. 25:183-e88. 2013
- The intestinal microbiome, probiotics and prebiotics in neurogastroenterology. Gut Microbes. 4:17-27. 2013
- Developmental alterations in CNS stress-related gene expression following postnatal immune activation. Neuroscience. 220:90-99. 2012
- Loss of class I MHC function alters behavior and stress reactivity. Journal of Neuroimmunology. 244:8-15. 2012
- Impact of Treadmill Running and Sex on Hippocampal Neurogenesis in the Mouse Model of Amyotrophic Lateral Sclerosis. PLoS ONE. 7:e36048-e36048. 2012
- Depression in Women. Journal of Clinical Psychiatry. 72:e1563-e1569. 2011
- Effects of intestinal microbiota on anxiety-like behavior.. Communicative and Integrative Biology. 4:492-494. 2011
- Reduced anxiety-like behavior and central neurochemical change in germ-free mice. Neurogastroenterology and Motility. 23:255-e119. 2011
- A developmental characterization of mesolimbocortical serotonergic gene expression changes following early immune challenge. Neuroscience. 171:734-746. 2010
- Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice. Gastroenterology. 139:2102-2112.e1. 2010
- Features of compulsive checking behavior mediated by nucleus accumbens and orbital frontal cortex. European Journal of Neuroscience. 32:1552-1563. 2010
- Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid. Neuroscience. 170:514-522. 2010
- The rapid effects of estrogen: a mini-review. Behavioural Pharmacology. 21:465-472. 2010
- Validation of an automated system for measuring anxiety-related behaviours in the elevated plus maze. Journal of Neuroscience Methods. 188:7-13. 2010
- Evidence for neuronal expression of functional Fc (ε and γ) receptors. Journal of Allergy and Clinical Immunology. 125:757-760. 2010
- Dietary amelioration of locomotor, neurotransmitter and mitochondrial aging. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.) Experimental Biology and Medicine. 235:66-76. 2010
- Prenatal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice. Neuroscience. 163:1201-1210. 2009
- Effects of gut microbiota on the brain: implications for psychiatry.. Journal of Psychiatry and Neuroscience Psychiatric Journal of the University of Ottawa. 34:230-231. 2009
- Role of gut-brain axis in persistent abnormal feeding behavior in mice following eradication ofHelicobacter pyloriinfection. American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 296:R587-R594. 2009
- Proclivity to self-injurious behavior in MRL-lpr mice: implications for autoimmunity-induced damage in the dopaminergic system. Molecular Psychiatry. 13:1043-1053. 2008
- Ether-a-go-go-related gene 3 is the main candidate for the E-4031-sensitive potassium current in the pacemaker interstitial cells of Cajal. American Journal of Physiology - Gastrointestinal and Liver Physiology. 295:G691-G699. 2008
- Disruption of T-cell immunoglobulin and mucin domain molecule (TIM)–1/TIM4 interaction as a therapeutic strategy in a dendritic cell–induced peanut allergy model. Journal of Allergy and Clinical Immunology. 122:55-61.e7. 2008
- Neurobiological Factors Linking Personality Traits and Major Depression. Canadian Journal of Psychiatry. 53:6-13. 2008
- Cotreatment with the kappa opioid agonist U69593 enhances locomotor sensitization to the D2/D3 dopamine agonist quinpirole and alters dopamine D2 receptor and prodynorphin mRNA expression in rats. Psychopharmacology. 194:485-496. 2007
- Distribution and prevalence of leukocyte phenotypes in brains of lupus-prone mice. Journal of Neuroimmunology. 179:26-36. 2006
- cDNA array reveals increased expression of glucose-dependent insulinotropic polypeptide following chronic clozapine treatment: role in atypical antipsychotic drug-induced adverse metabolic effects. Pharmacogenomics Journal. 6:131-140. 2006
- Expression of a killer cell receptor-like gene in plastic regions of the central nervous system. Journal of Neuroimmunology. 161:177-182. 2005
- Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures. Journal of Comparative Neurology. 476:91-102. 2004
- Kainic acid lesion-induced nigral neuronal death. Journal of Chemical Neuroanatomy. 26:65-73. 2003
- Induced neuronal expression of class I major histocompatibility complex mRNA in acute and chronic inflammation models. Journal of Neuroimmunology. 131:83-91. 2002
- GTP cyclohydrolase I induction in striatal astrocytes following intrastriatal kainic acid lesion. Journal of Chemical Neuroanatomy. 24:173-179. 2002
- Intracerebroventricular but not intravenous interleukin-1β induces widespread vascular-mediated leukocyte infiltration and immune signal mRNA expression followed by brain-wide glial activation. Neuroscience. 112:731-749. 2002
- Lipid peroxidation-mediated oxidative stress and dopamine neuronal apoptosis in the substantia nigra during development. Neurochemistry International. 39:127-133. 2001
- Evidence of deprenyl-insensitive apoptosis of nigral dopamine neurons during development. Developmental Brain Research. 120:95-98. 2000
- Differential induction of heat shock mRNA in oligodendrocytes, microglia, and astrocytes following hyperthermia. Brain Research Brain Research Protocols Molecular Brain Research. 45:207-218. 1997
- Intracellular localization of heat shock mRNAs (hsc70 and hsp70) to neural cell bodies and processes in the control and hyperthermic rabbit brain.. Journal of Neuroscience Research. 46:652-665. 1996
- Basal expression of stress-inducible hsp70 mRNA detected in hippocampal and cortical neurons of normal rabbit brain. Brain Research Brain Research Protocols Molecular Brain Research. 724:73-83. 1996
- Localization of constitutive and hyperthermia-inducible heat shock mRNAS (hsc70 and hsp70) in the rabbit cerebellum and brainstem by non-radioactive in situ hybridization. Journal of Neuroscience Research. 41:603-612. 1995
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book
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chapter
- Gut Microbiome and Behavior. International Review of Neurobiology. 49-65. 2016
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conference paper
- THE EFFICACY, SAFETY, AND TOLERABILITY OF PROBIOTICS ON SYMPTOMS OF DEPRESSION: RESULTS FROM A PILOT STUDY. Annales Nestle Annals of Nutrition and Metabolism. 55-55. 2018
- GENOME-WIDE ASSOCIATION STUDY IN DULOXETINE AND PLACEBO RESPONSE. European Neuropsychopharmacology. S245-S246. 2017
- GWAS-BASED MACHINE LEARNING APPROACH TO PREDICT DULOXETINE RESPONSE IN MAJOR DEPRESSIVE DISORDER. European Neuropsychopharmacology. S285-S286. 2017
- 751. The Role of Childhood Maltreatment in Depression: Overview of the Literature and Insights from the CAN-BIND Program. Biological Psychiatry. S304-S305. 2017
- 754. Inflammatory Markers as Mediators of the Association between Early Life Adversity and Hippocampal Volume in Adult Patients with depression: Findings from Phase 1 of the CAN-BIND Study. Biological Psychiatry. S306-S306. 2017
- Genome-Wide Association Study of Duloxetine and Placebo Response in Major Depressive Disorder. Genetic Epidemiology. 652-652. 2016
- Behaviour and neuroanatomy in Angelman Syndrome mice. International Journal of Developmental Neuroscience. 57-57. 2015
- S.20.04 Gut-brain communication: how the microbiome influences anxiety and depression. European Neuropsychopharmacology. S141-S141. 2015
- P.1.i.034 The impact of 5-HTTLPR and BDNF Val66Met on heterogeneity of intrinsic connectivity of amygdala in major depressive disorder. European Neuropsychopharmacology. S317-S317. 2014
- Gut-brain axis: How the microbiome influences anxiety and depression. International Journal of Neuropsychopharmacology. 27-27. 2014
- Amygdala Responses as Neuroimaging Endpoint Marker for Antidepressant Efficacy in Patients with Major Depression and High Risk Alleles of Serotonin Transporter Gene Polymorphism. Biological Psychiatry. 239S-240S. 2014
- The microbiome is necessary for normal gut intrinsic primary afferent neuron excitability. Neurogastroenterology and Motility. 12-13. 2011
- Gene Expression of Estrogen Receptor alpha and Serotonin Transporter in Women with Premenstrual Syndrome and Premenstrual Dysphoric Disorder. Biological Psychiatry. 55S-55S. 2010
- Risk Alleles of the Serotonin Transporter Polymorphism Predict Small Hippocampal Volumes in Major Depression. Biological Psychiatry. 232S-232S. 2009
- HEAT-SHOCK STRESS PROTEINS IN THE MAMMALIAN BRAIN. Journal of Neurochemistry. S190-S190. 1993