Journal article
Treatment-emergent and trajectory-based peripheral gene expression markers of antidepressant response
Abstract
Identifying biomarkers of antidepressant response may advance personalized treatment of major depressive disorder (MDD). We aimed to identify longitudinal changes in gene expression associated with response to antidepressants in a sample of MDD patients treated with escitalopram. Patients (N = 153) from the CAN-BIND-1 cohort were treated for 8 weeks, and depressive symptoms were assessed using the Montgomery-Åsberg Depression Rating Scale at 0, …
Authors
Fiori LM; Orri M; Aouabed Z; Théroux JF; Lin R; Nagy C; Frey BN; Lam RW; MacQueen GM; Milev R
Journal
Translational Psychiatry, Vol. 11, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41398-021-01564-8
ISSN
2158-3188