Journal article
Mouse MRI shows brain areas relatively larger in males emerge before those larger in females
Abstract
Sex differences exist in behaviors, disease and neuropsychiatric disorders. Sexual dimorphisms however, have yet to be studied across the whole brain and across a comprehensive time course of postnatal development. Here, we use manganese-enhanced MRI (MEMRI) to longitudinally image male and female C57BL/6J mice across 9 time points, beginning at postnatal day 3. We recapitulate findings on canonically dimorphic areas, demonstrating MEMRI’s …
Authors
Qiu LR; Fernandes DJ; Szulc-Lerch KU; Dazai J; Nieman BJ; Turnbull DH; Foster JA; Palmert MR; Lerch JP
Journal
Nature Communications, Vol. 9, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41467-018-04921-2
ISSN
2041-1723