Journal article
Genome-wide association studies of placebo and duloxetine response in major depressive disorder
Abstract
We investigated variants associated with treatment response in depressed patients treated with either the antidepressant duloxetine or placebo using a genome-wide approach. Our sample (N=391) included individuals aged 18–75 years, diagnosed with major depressive disorder and treated with either duloxetine or placebo for up to 8 weeks. We conducted genome-wide associations for treatment response as operationalized by percentage change in …
Authors
Maciukiewicz M; Marshe VS; Tiwari AK; Fonseka TM; Freeman N; Kennedy JL; Rotzinger S; Foster JA; Kennedy SH; Müller DJ
Journal
The Pharmacogenomics Journal, Vol. 18, No. 3, pp. 406–412
Publisher
Springer Nature
Publication Date
5 2018
DOI
10.1038/tpj.2017.29
ISSN
1470-269X