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Association Between Side Effects and Blood...
Journal article

Association Between Side Effects and Blood microRNA Expression Levels and Their Targeted Pathways in Patients With Major Depressive Disorder Treated by a Selective Serotonin Reuptake Inhibitor, Escitalopram: A CAN-BIND-1 Report

Abstract

INTRODUCTION: Antidepressant drugs are effective therapies for major depressive disorder; however, they are frequently associated with side effects. Although there is some evidence for a relationship between genetic variation and side effects, little is known regarding the role of dynamic molecular factors as moderators of side effects. The aim of this study was to assess microRNA (miRNA) changes associated with side effects during escitalopram …

Authors

Yrondi A; Fiori LM; Frey BN; Lam RW; MacQueen GM; Milev R; Müller DJ; Foster JA; Kennedy SH; Turecki G

Journal

The International Journal of Neuropsychopharmacology, Vol. 23, No. 2, pp. 88–95

Publisher

Oxford University Press (OUP)

Publication Date

March 25, 2020

DOI

10.1093/ijnp/pyz066

ISSN

1461-1457