Homeodomain Proteins Concept

subject area of

• 3 minutes to precisely measure morphogen concentration  Journal Articles
• A point mutation in the neu1 promoter recruits an ectopic repressor, Nkx3.2 and results in a mouse model of sialidase deficiency  Journal Articles
• A role for GPx3 in activity of normal and leukemia stem cells  Journal Articles
• AP-2αTranscription Factor Is Required for Early Morphogenesis of the Lens Vesicle  Journal Articles
• AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development  Journal Articles
• Activation of the Hedgehog Signaling Pathway in the Developing Lens Stimulates EctopicFoxE3Expression and Disruption in Fiber Cell Differentiation  Journal Articles
• Amino Acid Substitutions in the Herpes Simplex Virus Transactivator VP16 Uncouple Direct Protein-Protein Interaction and DNA Binding from Complex Assembly and Transactivation  Journal Articles
• An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity  Journal Articles
• Arkadia enhances nodal-related signalling to induce mesendoderm.  Journal Articles
• BCL-2: the pendulum of the cell fate.  Journal Articles
• Blood flow reprograms lymphatic vessels to blood vessels  Journal Articles
• Brief Report: Ectopic Expression of Nup98-HoxA10 Augments Erythroid Differentiation of Human Embryonic Stem Cells  Journal Articles
• CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions  Journal Articles
• Cdx2 Polymorphism Affects the Activities of Vitamin D Receptor in Human Breast Cancer Cell Lines and Human Breast Carcinomas  Journal Articles
• Cell autonomous roles for AP‐2α in lens vesicle separation and maintenance of the lens epithelial cell phenotype  Journal Articles
• Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex  Journal Articles
• Characterization of the mouse lysosomal sialidase promoter  Journal Articles
• Complex genetic interactions govern the temporal effects of Antennapedia on antenna-to-leg transformations in Drosophila melanogaster  Journal Articles
• Defective insulin maturation in patients with type 2 diabetes  Journal Articles
• Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions  Journal Articles
• Discovery of Novel Hypermethylated Genes in Prostate Cancer Using Genomic CpG Island Microarrays  Journal Articles
• Dissection of lin-11 enhancer regions in Caenorhabditis elegans and other nematodes  Journal Articles
• Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms  Journal Articles
• Evidence for canalization of Distal‐less function in the leg of Drosophila melanogaster  Journal Articles
• Excess of Rare Variants in Non–Genome-Wide Association Study Candidate Genes in Patients With Hypertriglyceridemia  Journal Articles
• Expression of the drosophila gene disconnected using the UAS/GAL4 system  Journal Articles
• Fetal hemoglobin in sickle cell anemia: Genetic studies of the Arab-Indian haplotype  Journal Articles
• Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopicHOXB4expression  Journal Articles
• Genetic Control of Vulval Development inCaenorhabditis briggsae  Journal Articles
• Genetic Dissection of Behavior: Modulation of Locomotion by Light in theDrosophila melanogasterLarva Requires Genetically Distinct Visual System Functions  Journal Articles
• Genetic Dissection of Photoreceptor Subtype Specification by the Drosophila melanogaster Zinc Finger Proteins Elbow and No ocelli  Journal Articles
• Genetic analysis indicates that transcription factors AP-2alpha and Pax6 cooperate in the normal patterning and morphogenesis of the lens.  Journal Articles
• Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity  Journal Articles
• Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer  Journal Articles
• Hierarchical and Ontogenic Positions Serve to Define the Molecular Basis of Human Hematopoietic Stem Cell Behavior  Journal Articles
• High Mobility of Bicoid Captured by Fluorescence Correlation Spectroscopy: Implication for the Rapid Establishment of Its Gradient  Journal Articles
• Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia  Journal Articles
• Increased frequency of β cells with abnormal NKX6.1 expression in type 2 diabetes but not in subjects with higher risk for type 2 diabetes  Journal Articles
• Innate Immune Processes Are Sufficient for Driving Cigarette Smoke–Induced Inflammation in Mice  Journal Articles
• Intron-specific patterns of divergence of lin-11 regulatory function in the C. elegans nervous system  Journal Articles
• Isolation and Characterization of Mesenchymal Stem Cells From the Sub-Amniotic Human Umbilical Cord Lining Membrane  Journal Articles
• Mainstream Model of Genetic Testing for Prostate Cancer at a Large Tertiary Cancer Centre  Journal Articles
• Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia  Journal Articles
• Minimal ProtoHox cluster inferred from bilaterian and cnidarian Hox complements  Journal Articles
• Multiple Imprinted and Stemness Genes Provide a Link between Normal and Tumor Progenitor Cells of the Developing Human Kidney  Journal Articles
• Mutual regulation of the Drosophila disconnected (disco) and Distal-less (Dll) genes contributes to proximal-distal patterning of antenna and leg  Journal Articles
• Normalization of obesity-associated insulin resistance through immunotherapy  Journal Articles
• Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells  Journal Articles
• OP9 Stroma Augments Survival of Hematopoietic Precursors and Progenitors During Hematopoietic Differentiation from Human Embryonic Stem Cells  Journal Articles
• On the importance of protein diffusion in biological systems: The example of the Bicoid morphogen gradient  Journal Articles
• Paraspinal muscle ladybird homeobox 1 (LBX1) in adolescent idiopathic scoliosis: a cross-sectional study  Journal Articles
• Pattern specification and immune response transcriptional signatures of pericardial and subcutaneous adipose tissue.  Journal Articles
• Pluripotent Transcription Factors Possess Distinct Roles in Normal versus Transformed Human Stem Cells  Journal Articles
• Precision in a rush: Trade-offs between reproducibility and steepness of the hunchback expression pattern  Journal Articles
• RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity  Journal Articles
• Reconstitution of immune cell in liver and lymph node of adult- and newborn-engrafted humanized mice  Journal Articles
• Role of ZEB Family Members in Proliferation, Metastasis, and Chemoresistance of Prostate Cancer Cells: Revealing Signaling Networks  Journal Articles
• Roles for MSI2 and PROX1 in hematopoietic stem cell activity  Journal Articles
• Search for the sex-determining switch in monotremes: Mapping WT1, SF1, LHX1, LHX2, FGF9, WNT4, RSPO1 and GATA4 in platypus  Journal Articles
• Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription  Journal Articles
• The C. elegans LIM homeobox gene lin-11 specifies multiple cell fates during vulval development  Journal Articles
• The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2  Journal Articles
• The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression  Journal Articles
• The Histone Demethylase KDM5b/JARID1b Plays a Role in Cell Fate Decisions by Blocking Terminal Differentiation  Journal Articles
• The POZ-ZF Transcription Factor Kaiso (ZBTB33) Induces Inflammation and Progenitor Cell Differentiation in the Murine Intestine  Journal Articles
• The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation  Journal Articles
• The time to measure positional information: maternal Hunchback is required for the synchrony of the Bicoid transcriptional response at the onset of zygotic transcription  Journal Articles
• Tissue-Specific Regulation of the LIM Homeobox Gene lin-11 during Development of the Caenorhabditis elegans Egg-Laying System  Journal Articles
• Toxicity Associated with Repeated Administration of First-Generation Adenovirus Vectors Does Not Occur with a Helper-Dependent Vector  Journal Articles
• Transcription Factors Pax6 and AP-2α Interact To Coordinate Corneal Epithelial Repair by Controlling Expression of Matrix Metalloproteinase Gelatinase B  Journal Articles
• δEF1 repressor controls selectively p53 family members during differentiation  Journal Articles