Journal article
Reconstitution of immune cell in liver and lymph node of adult- and newborn-engrafted humanized mice
Abstract
BackgroundHumanized mouse models are an increasingly popular preclinical model to study the human immune response in a biological system. There are a variety of protocols to generate these mice, each differing in the strain of the recipient, source of hematopoietic stem cells, and mode of transplantation. Though there is well-documented reconstitution information regarding the spleen, blood, and bone marrow, there is little information …
Authors
Dykstra C; Lee AJ; Lusty EJ; Shenouda MM; Shafai M; Vahedi F; Chew MV; Collins S; Ashkar AA
Journal
BMC Immunology, Vol. 17, No. 1,
Publisher
Springer Nature
Publication Date
12 2016
DOI
10.1186/s12865-016-0157-9
ISSN
1471-2172