Journal article
Mutual regulation of the Drosophila disconnected (disco) and Distal-less (Dll) genes contributes to proximal-distal patterning of antenna and leg
Abstract
The Drosophila disconnected (disco) gene encodes a C2H2-type zinc finger transcription factor required for the development of the central and peripheral nervous systems. We report that disco participates in a positive feedback loop with the Dll gene, a master regulator of ventral appendage development. Dll function is not only required for proper disco expression in antenna and leg discs, but is also sufficient for ectopic expression of disco …
Authors
Dey BK; Zhao X-L; Popo-Ola E; Campos AR
Journal
Cell and Tissue Research, Vol. 338, No. 2,
Publisher
Springer Nature
Publication Date
November 2009
DOI
10.1007/s00441-009-0865-z
ISSN
0302-766X