Journal article
Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer
Abstract
INTRODUCTION: The HOXB13 pGly84Glu mutation has recently been associated with an increased risk of prostate cancer but the association of other cancer sites with this allele has not been assessed. Data has suggested that HOXB13 expression levels are decreased in colorectal cancer (CRC) cell lines indicating this gene may be involved in colorectal tumourigenesis.
METHODS: To evaluate a potential association of this mutation with CRC, we …
Authors
Akbari MR; Anderson LN; Buchanan DD; Clendenning M; Jenkins MA; Win AK; Hopper JL; Giles GG; Nam R; Narod S
Journal
Cancer Epidemiology, Vol. 37, No. 4, pp. 424–427
Publisher
Elsevier
Publication Date
August 2013
DOI
10.1016/j.canep.2013.03.003
ISSN
1877-7821