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Brief Report: Ectopic Expression of Nup98‐HoxA10...
Journal article

Brief Report: Ectopic Expression of Nup98‐HoxA10 Augments Erythroid Differentiation of Human Embryonic Stem Cells

Abstract

Hox genes encode highly conserved transcription factors that have been implicated in hematopoietic development and self-renewal of hematopoietic stem cells (HSCs) and hematopoietic development. The potency of NUP98-HOXA10hd (NA10) on adult murine bone marrow HSC self-renewal prompted us to examine its effect on specification and proliferation of hematopoietic cells derived from human embryonic stem cells (hESCs). Here, we demonstrate that …

Authors

Ji J; Risueño RM; Hong S; Allan D; Rosten P; Humphries K; Bhatia M

Journal

Stem Cells, Vol. 29, No. 4, pp. 736–741

Publisher

Oxford University Press (OUP)

Publication Date

April 1, 2011

DOI

10.1002/stem.622

ISSN

1066-5099