Epigenesis, Genetic Concept

subject area of

• 5-Azacytidine upregulates melatonin MT1 receptor expression in rat C6 glioma cells: oncostatic implications  Journal Articles
• WNT2promoter methylation in human placenta is associated with low birthweight percentile in the neonate  Journal Articles
• A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor  Journal Articles
• A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer  Journal Articles
• A review of the peripheral levels of regulation by thyroid hormone  Journal Articles
• Aberrant Epigenetic Regulation: A Central Contributor to Lung Carcinogenesis and a New Therapeutic Target  Journal Articles
• Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time  Journal Articles
• Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD  Journal Articles
• An update on immunologic mechanisms in the respiratory mucosa in response to air pollutants  Journal Articles
• Artificial sperm and epigenetic reprogramming  Journal Articles
• Assessing reproductive effects and epigenetic responses in Austrolebias charrua exposed to Roundup Transorb®: Insights from miRNA profiling and molecular interaction analysis.  Journal Articles
• Association of Neighborhood Deprivation and Depressive Symptoms With Epigenetic Age Acceleration: Evidence From the Canadian Longitudinal Study on Aging  Journal Articles
• Autism Spectrum Disorders and Epigenetics  Journal Articles
• BAFopathies’ DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin–Siris and Nicolaides–Baraitser syndromes  Journal Articles
• BMI1 is a therapeutic target in recurrent medulloblastoma  Conferences
• Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation  Journal Articles
• Big brown bats experience slower epigenetic ageing during hibernation  Journal Articles
• Burn-induced hypermetabolism and skeletal muscle dysfunction  Journal Articles
• CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions  Journal Articles
• Cell Fate Potential of Human Pluripotent Stem Cells Is Encoded by Histone Modifications  Journal Articles
• Clinically relevant concentrations of valproic acid modulate melatonin MT1 receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells  Journal Articles
• Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer  Journal Articles
• Consistent cord blood DNA methylation signatures of gestational age between South Asian and white European cohorts  Journal Articles
• Control of breathing and the circulation in high-altitude mammals and birds  Journal Articles
• Cumulative risks predict epigenetic age in adult survivors of extremely low birth weight  Journal Articles
• DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes  Journal Articles
• DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome  Journal Articles
• DNA methylation predicts age and provides insight into exceptional longevity of bats  Journal Articles
• DNA methylation predicts stroke outcome better  Journal Articles
• Diet and depression: exploring the biological mechanisms of action  Journal Articles
• Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice  Journal Articles
• Discovery of Novel Hypermethylated Genes in Prostate Cancer Using Genomic CpG Island Microarrays  Journal Articles
• Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men  Journal Articles
• EBV transformation and cell culturing destabilizes DNA methylation in human lymphoblastoid cell lines  Journal Articles
• Endocrine Toxicants with Emphasis on Human Health Risks  Journal Articles
• Epigenetic Age and the Risk of Incident Atrial Fibrillation  Journal Articles
• Epigenetic Profiling in Severe Sepsis: A Pilot Study of DNA Methylation Profiles in Critical Illness*  Journal Articles
• Epigenetic Profiling in Severe Sepsis: A Pilot Study of DNA Methylation Profiles in Critical Illness.  Journal Articles
• Epigenetic Regulation of Tumor Necrosis Factor Alpha  Journal Articles
• Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging  Journal Articles
• Epigenetic induction of melatonin MT 1 receptors by valproate: Neurotherapeutic implications  Journal Articles
• Epigenetic maintenance strategies after allogeneic stem cell transplantation in acute myeloid leukemia  Journal Articles
• Epigenetic mechanisms of melatonin action in human SH-SY5Y neuroblastoma cells  Journal Articles
• Epigenetic modification of CSDE1 locus dictates immune recognition of nascent tumorigenic cells  Journal Articles
• Epigenetic profiling of growth plate chondrocytes sheds insight into regulatory genetic variation influencing height  Journal Articles
• Epigenetic regulation of melatonin receptors in neuropsychiatric disorders  Journal Articles
• Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.  Journal Articles
• Epigenetic silencing of miR-145-5p contributes to brain metastasis  Journal Articles
• Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells  Journal Articles
• Epigenetic therapy inhibits metastases by disrupting premetastatic niches  Journal Articles
• Epigenetics of Sepsis  Journal Articles
• Epigenomic alterations define lethal CIMP-positive ependymomas of infancy  Journal Articles
• Extremely Low Birth Weight and Accelerated Biological Aging  Journal Articles
• Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants  Journal Articles
• GWAS of biological aging to find longevity genes in schizophrenia.  Journal Articles
• Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon Pathway  Journal Articles
• Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets  Journal Articles
• Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes  Journal Articles
• Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo  Journal Articles
• Genomics and epigenomics in pediatric oncology and clinical laboratory genetics  Journal Articles
• Healthy Foundations Study: a randomised controlled trial to evaluate biological embedding of early-life experiences  Journal Articles
• Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease  Journal Articles
• Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma  Journal Articles
• Human Embryonic Stem Cell-Derived Hematopoietic Cells Maintain Core Epigenetic Machinery of the Polycomb Group/Trithorax Group Complexes Distinctly from Functional Adult Hematopoietic Stem Cells  Journal Articles
• Hypothalamic-Pituitary-Adrenal Axis Dysfunction and Illness Progression in Bipolar Disorder  Journal Articles
• Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy  Journal Articles
• Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome  Journal Articles
• Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes  Journal Articles
• Increased incidence of non‐alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis  Journal Articles
• Induction of Neurotrophic and Differentiation Factors in Neural Stem Cells by Valproic Acid  Journal Articles
• Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors  Journal Articles
• Key Developments in Endocrine Disrupter Research and Human Health  Journal Articles
• Landscape review of current HIV ‘kick and kill’ cure research - some kicking, not enough killing  Journal Articles
• Leptin as mediator of the effects of developmental programming  Journal Articles
• Long‐Term Effects of Early‐Life Exposure to Environmental Oestrogens on Ovarian Function: Role of Epigenetics  Journal Articles
• Low-Dose Ionizing Radiation Exposure, Oxidative Stress and Epigenetic Programing of Health and Disease  Journal Articles
• Maternal Obesity and Developmental Programming of Metabolic Disorders in Offspring: Evidence from Animal Models  Journal Articles
• Maternal depression is associated with DNA methylation changes in cord blood T lymphocytes and adult hippocampi  Journal Articles
• Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry  Preprints
• Melatonin induces histone hyperacetylation in the rat brain  Journal Articles
• Metabolic and co-expression network-based analyses associated with nitrate response in rice  Journal Articles
• Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells  Journal Articles
• Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes  Journal Articles
• Multilocus loss of DNA methylation in individuals with mutations in the histone H3 Lysine 4 Demethylase KDM5C  Journal Articles
• Next Wave of Targets in the Treatment of Advanced Renal Cell Carcinoma  Journal Articles
• On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations  Journal Articles
• Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas  Journal Articles
• Placental NEGR1 DNA methylation is associated with BMI and neurodevelopment in preschool-age children  Journal Articles
• Pluripotent human stem cell lines: what we can learn about cancer initiation  Journal Articles
• Radiation and the regulatory landscape of neo2-Darwinism  Journal Articles
• Radiation induces stress and transgenerational impacts in the cricket, Acheta domesticus  Journal Articles
• Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth  Journal Articles
• Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity  Journal Articles
• Reciprocal deletion and duplication at 2q23.1 indicates a role for MBD5 in autism spectrum disorder  Journal Articles
• Role of environmental factors and epigenetics in autism spectrum disorders  Chapters
• SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females  Journal Articles
• Severe presentation of Beckwith–Wiedemann syndrome associated with high levels of constitutional paternal uniparental disomy for chromosome 11p15  Journal Articles
• Somatic transcriptome priming gates lineage-specific differentiation potential of human-induced pluripotent stem cell states  Journal Articles
• Stress-related cellular pathophysiology as a crosstalk risk factor for neurocognitive and psychiatric disorders  Journal Articles
• The Epigenetic Regulation of SOX9 by miR‐145 in Human Chondrosarcoma  Journal Articles
• The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO  Journal Articles
• The Methyltransferase Smyd1 Mediates LPS-Triggered Up-Regulation of IL-6 in Endothelial Cells  Journal Articles
• The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells  Journal Articles
• The Role of Nutrient-Based Epigenetic Changes in Buffering Against Stress, Aging, and Alzheimer’s Disease  Journal Articles
• The association between adverse childhood experiences and epigenetic age acceleration in the Canadian longitudinal study on aging (CLSA)  Journal Articles
• The circRNA–microRNA code: emerging implications for cancer diagnosis and treatment  Journal Articles
• The post-genomic era: workshop on chromatin immunoprecipitation-related techniques  Journal Articles
• The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study  Journal Articles
• The role of epigenetics in multi‐generational transmission of asthma: An NIAID workshop report‐based narrative review  Journal Articles
• Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation  Journal Articles
• Thyroid hormone links environmental signals to DNA methylation  Journal Articles
• Towards precision medicine in generalized anxiety disorder: Review of genetics and pharmaco(epi)genetics  Journal Articles
• Wasting away: AJP-Cell Physiology initiates thematic reviews on skeletal muscle wasting  Journal Articles
• YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer  Journal Articles