Epigenesis, Genetic Concept

subject area of

• 5-Azacytidine upregulates melatonin MT1 receptor expression in rat C6 glioma cells: oncostatic implications  Academic Article
• WNT2promoter methylation in human placenta is associated with low birthweight percentile in the neonate  Academic Article
• A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor  Academic Article
• A review of the peripheral levels of regulation by thyroid hormone  Academic Article
• Aberrant Epigenetic Regulation: A Central Contributor to Lung Carcinogenesis and a New Therapeutic Target  Academic Article
• Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time  Academic Article
• Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD  Academic Article
• An update on immunologic mechanisms in the respiratory mucosa in response to air pollutants  Academic Article
• Artificial sperm and epigenetic reprogramming  Academic Article
• Autism Spectrum Disorders and Epigenetics  Academic Article
• BAFopathies’ DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin–Siris and Nicolaides–Baraitser syndromes  Academic Article
• BMI1 is a therapeutic target in recurrent medulloblastoma  Conference Paper
• Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation  Academic Article
• Big brown bats experience slower epigenetic ageing during hibernation  Academic Article
• Burn-induced hypermetabolism and skeletal muscle dysfunction  Academic Article
• CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions  Academic Article
• Cell Fate Potential of Human Pluripotent Stem Cells Is Encoded by Histone Modifications  Academic Article
• Clinically relevant concentrations of valproic acid modulate melatonin MT1 receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells  Academic Article
• Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer  Academic Article
• Control of breathing and the circulation in high-altitude mammals and birds  Academic Article
• Cumulative risks predict epigenetic age in adult survivors of extremely low birth weight  Academic Article
• DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes  Academic Article
• DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome  Academic Article
• DNA methylation predicts age and provides insight into exceptional longevity of bats  Academic Article
• DNA methylation predicts stroke outcome better  Academic Article
• Diet and depression: exploring the biological mechanisms of action  Academic Article
• Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice  Academic Article
• Discovery of Novel Hypermethylated Genes in Prostate Cancer Using Genomic CpG Island Microarrays  Academic Article
• Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men  Academic Article
• EBV transformation and cell culturing destabilizes DNA methylation in human lymphoblastoid cell lines  Academic Article
• Endocrine Toxicants with Emphasis on Human Health Risks  Academic Article
• Epigenetic Age and the Risk of Incident Atrial Fibrillation  Academic Article
• Epigenetic Profiling in Severe Sepsis: A Pilot Study of DNA Methylation Profiles in Critical Illness*  Academic Article
• Epigenetic Profiling in Severe Sepsis: A Pilot Study of DNA Methylation Profiles in Critical Illness.  Academic Article
• Epigenetic Regulation of Tumor Necrosis Factor Alpha  Academic Article
• Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging  Academic Article
• Epigenetic induction of melatonin MT 1 receptors by valproate: Neurotherapeutic implications  Academic Article
• Epigenetic maintenance strategies after allogeneic stem cell transplantation in acute myeloid leukemia  Academic Article
• Epigenetic mechanisms of melatonin action in human SH-SY5Y neuroblastoma cells  Academic Article
• Epigenetic modification of CSDE1 locus dictates immune recognition of nascent tumorigenic cells  Academic Article
• Epigenetic profiling of growth plate chondrocytes sheds insight into regulatory genetic variation influencing height  Academic Article
• Epigenetic regulation of melatonin receptors in neuropsychiatric disorders  Academic Article
• Epigenetic silencing of miR-145-5p contributes to brain metastasis  Academic Article
• Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells  Academic Article
• Epigenetic therapy inhibits metastases by disrupting premetastatic niches  Academic Article
• Epigenetics of Sepsis  Academic Article
• Epigenomic alterations define lethal CIMP-positive ependymomas of infancy  Academic Article
• Extremely Low Birth Weight and Accelerated Biological Aging  Academic Article
• Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants  Academic Article
• Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon Pathway  Academic Article
• Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets  Academic Article
• Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes  Academic Article
• Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo  Academic Article
• Genomics and epigenomics in pediatric oncology and clinical laboratory genetics  Academic Article
• Gross motor problems and psychiatric disorders in children  Academic Article
• Healthy Foundations Study: a randomised controlled trial to evaluate biological embedding of early-life experiences  Academic Article
• Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease  Academic Article
• Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma  Academic Article
• Human Embryonic Stem Cell-Derived Hematopoietic Cells Maintain Core Epigenetic Machinery of the Polycomb Group/Trithorax Group Complexes Distinctly from Functional Adult Hematopoietic Stem Cells  Academic Article
• Hypothalamic-Pituitary-Adrenal Axis Dysfunction and Illness Progression in Bipolar Disorder  Academic Article
• Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy  Academic Article
• Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome  Academic Article
• Improved in vitro development of cloned bovine embryos using S -adenosylhomocysteine, a non-toxic epigenetic modifying reagent  Academic Article
• Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes  Academic Article
• Increased incidence of non-alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis  Academic Article
• Induction of Neurotrophic and Differentiation Factors in Neural Stem Cells by Valproic Acid  Academic Article
• Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors  Academic Article
• Key Developments in Endocrine Disrupter Research and Human Health  Academic Article
• Landscape review of current HIV ‘kick and kill’ cure research - some kicking, not enough killing  Academic Article
• Leptin as mediator of the effects of developmental programming  Academic Article
• Long‐Term Effects of Early‐Life Exposure to Environmental Oestrogens on Ovarian Function: Role of Epigenetics  Academic Article
• Low-Dose Ionizing Radiation Exposure, Oxidative Stress and Epigenetic Programing of Health and Disease  Academic Article
• Maternal Obesity and Developmental Programming of Metabolic Disorders in Offspring: Evidence from Animal Models  Academic Article
• Maternal depression is associated with DNA methylation changes in cord blood T lymphocytes and adult hippocampi  Academic Article
• Melatonin induces histone hyperacetylation in the rat brain  Academic Article
• Metabolic and co-expression network-based analyses associated with nitrate response in rice  Academic Article
• MiR-191 as a Key Molecule in Aneurysmal Aortic Remodeling  Academic Article
• Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells  Academic Article
• Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes  Academic Article
• Multilocus loss of DNA methylation in individuals with mutations in the histone H3 Lysine 4 Demethylase KDM5C  Academic Article
• Next Wave of Targets in the Treatment of Advanced Renal Cell Carcinoma  Academic Article
• On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations  Academic Article
• Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas  Academic Article
• Placental NEGR1 DNA methylation is associated with BMI and neurodevelopment in preschool-age children  Academic Article
• Pluripotent human stem cell lines: what we can learn about cancer initiation  Academic Article
• Radiation and the regulatory landscape of neo2-Darwinism  Academic Article
• Radiation induces stress and transgenerational impacts in the cricket, Acheta domesticus  Academic Article
• Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth  Academic Article
• Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity  Academic Article
• Reciprocal deletion and duplication at 2q23.1 indicates a role for MBD5 in autism spectrum disorder  Academic Article
• Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood  Academic Article
• Role of environmental factors and epigenetics in autism spectrum disorders  Chapter
• SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females  Academic Article
• Severe presentation of Beckwith–Wiedemann syndrome associated with high levels of constitutional paternal uniparental disomy for chromosome 11p15  Academic Article
• Somatic transcriptome priming gates lineage-specific differentiation potential of human-induced pluripotent stem cell states  Academic Article
• The Epigenetic Regulation of SOX9 by miR-145 in Human Chondrosarcoma  Academic Article
• The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO  Academic Article
• The Methyltransferase Smyd1 Mediates LPS-Triggered Up-Regulation of IL-6 in Endothelial Cells  Academic Article
• The Role of Nutrient-Based Epigenetic Changes in Buffering Against Stress, Aging, and Alzheimer’s Disease  Academic Article
• The association between adverse childhood experiences and epigenetic age acceleration in the Canadian longitudinal study on aging (CLSA)  Academic Article
• The circRNA–microRNA code: emerging implications for cancer diagnosis and treatment  Academic Article
• The post-genomic era: workshop on chromatin immunoprecipitation-related techniques  Academic Article
• The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study  Academic Article
• The role of epigenetics in multi‐generational transmission of asthma: An NIAID workshop report‐based narrative review  Academic Article
• Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation  Academic Article
• Towards precision medicine in generalized anxiety disorder: Review of genetics and pharmaco(epi)genetics  Academic Article
• Wasting Away: AJP Cell Initiates Thematic Reviews on Skeletal Muscle Wasting  Academic Article
• YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer  Academic Article