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Maternal depression is associated with DNA...
Journal article

Maternal depression is associated with DNA methylation changes in cord blood T lymphocytes and adult hippocampi

Abstract

Depression affects 10–15% of pregnant women and has been associated with preterm delivery and later developmental, behavioural and learning disabilities. We tested the hypothesis that maternal depression is associated with DNA methylation alterations in maternal T lymphocytes, neonatal cord blood T lymphocytes and adult offspring hippocampi. Genome-wide DNA methylation of CD3+ T lymphocytes isolated from 38 antepartum maternal and 44 neonatal …

Authors

Nemoda Z; Massart R; Suderman M; Hallett M; Li T; Coote M; Cody N; Sun ZS; Soares CN; Turecki G

Journal

Translational Psychiatry, Vol. 5, No. 4, pp. e545–e545

Publisher

Springer Nature

Publication Date

April 2015

DOI

10.1038/tp.2015.32

ISSN

2158-3188