Journal article
The Epigenetic Regulation of SOX9 by miR‐145 in Human Chondrosarcoma
Abstract
Chondrosarcoma is the most common primary bone malignancy in the adult population with a high rate of pulmonary metastasis. Chondrosarcoma is managed with surgical excision as the tumors do not respond well to conventional chemotherapy or radiation therapy. Thus, there exists a dire need to develop systemic treatment options to target chondrosarcoma cells for metastatic spread. We hypothesized that the expression of miR-145 is low in …
Authors
Mak IWY; Singh S; Turcotte R; Ghert M
Journal
Journal of Cellular Biochemistry, Vol. 116, No. 1, pp. 37–44
Publisher
Wiley
Publication Date
January 2015
DOI
10.1002/jcb.24940
ISSN
0730-2312