Journal article
The association between adverse childhood experiences and epigenetic age acceleration in the Canadian longitudinal study on aging (CLSA)
Abstract
Research examining the association between exposure to a wide range of adverse childhood experiences (ACEs) and accelerated biological aging in older adults is limited. The purpose of this study was to examine the association of ACEs, both as a cumulative score and individual forms of adversity, with epigenetic age acceleration assessed using the DNA methylation (DNAm) GrimAge and DNAm PhenoAge epigenetic clocks in middle and older-aged adults. …
Authors
Joshi D; Gonzalez A; Lin D; Raina P
Journal
Aging Cell, Vol. 22, No. 2,
Publisher
Wiley
Publication Date
February 2023
DOI
10.1111/acel.13779
ISSN
1474-9718