Stereoisomerism Concept

subject area of

• A Stereoselective Hydroxylation Step of Alkaloid Biosynthesis by a Unique Cytochrome P450 in Catharanthus roseus  Academic Article
• A Versatile Endoribonuclease Mimic Made of DNA: Characteristics and Applications of the 8-17 RNA-Cleaving DNAzyme  Academic Article
• A proposal for an extended dual descriptor: a possible solution when Frontier Molecular Orbital Theory fails  Academic Article
• A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents  Academic Article
• A sensitive signal-on electrochemiluminescence sensor based on a nanocomposite of polypyrrole-Gd2O3 for the determination of L-cysteine in biological fluids  Academic Article
• Allosteric Modulation of the Dopamine D₂ Receptor by Pro-Leu-Gly-NH₂ Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II β-Turn Conformation  Academic Article
• Allosteric Modulation of the Dopamine Receptor by Conformationally Constrained Type VI β-Turn Peptidomimetics of Pro-Leu-Gly-NH₂  Academic Article
• Altered levels of antithrombin III and fibrinogen in the aortic wall of the alloxan-induced diabetic rabbit: evidence of a prothrombotic state.  Academic Article
• Amino Acid Racemization and the Preservation of Ancient DNA  Academic Article
• Amino acid racemization in amber-entombed insects: Implications for DNA preservation  Academic Article
• Autocatalytic Replication and Homochirality in Biopolymers: Is Homochirality a Requirement of Life or a Result of It?  Academic Article
• Biosynthesis of the piperidine nucleus. Incorporation of chirally labeled cadaverine-1-3H  Academic Article
• CP-96,345, but not its stereoisomer, CP-96,344, blocks the nociceptive responses to intrathecally administered substance P and to noxious thermal and chemical stimuli in the rat  Academic Article
• Cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat  Academic Article
• Chimeric Streptogramin-Tyrocidine Antibiotics that Overcome Streptogramin Resistance  Academic Article
• Chirality in antirheumatic drugs  Academic Article
• Circular dichroism (CD) studies of antagonists derived from parathyroid hormone-related protein  Academic Article
• Collagen-Based Structures Containing the Peptoid Residue N-Isobutylglycine (Nleu):  Conformational Analysis of Gly-Nleu-Pro Sequences by ¹H-NMR and Molecular Modeling  Academic Article
• Comprehensive Radiolabeling, Stability, and Tissue Distribution Studies of Technetium-99m Single Amino Acid Chelates (SAAC)  Academic Article
• Conformations of poly-L-valine in solution  Academic Article
• Contractile activity in intestinal muscle evokes action potential discharge in guinea‐pig myenteric neurons  Academic Article
• Crystal structure of cGMP‐dependent protein kinase Iβ cyclic nucleotide‐binding‐B domain : Rp‐cGMPS complex reveals an apo‐like, inactive conformation  Academic Article
• Cyclopolymerization Reactions of Diallyl Monomers: Exploring Electronic and Steric Effects Using DFT Reactivity Indices  Academic Article
• Diels-Alder Additions as Mechanistic Probes–Interception of Silyl-Isoindenes: Organometallic Derivatives of Polyphenylated Cycloheptatrienes and Related Seven-Membered Rings  Academic Article
• Differential Toxicity of Cis andTrans Isomers of Dichlorodiammineplatinum  Academic Article
• Directed Remote Aromatic Metalations: Mechanisms and Driving Forces  Academic Article
• Does the left hand know what the right hand is doing? or Clinical pharmacology: the use of optically pure (R or S) forms of chiral drugs rather than racemic mixtures.  Academic Article
• Effect of R and S Enantiomers of Naproxen on Aggregation and Thromboxane Production in Human Platelets  Academic Article
• Effects of intravenously administered enantiomers of baclofen on functionally identified units in lumbar dorsal horn of the spinal cat  Academic Article
• Effects of phaclofen and the enantiomers of baclofen on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat  Academic Article
• Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation  Academic Article
• Electrophoretic deposition of TiO2 and composite TiO2–MnO2 films using benzoic acid and phenolic molecules as charging additives  Academic Article
• Electrophysiological Evidence That Neurokinin A Acts Via NK-1 Receptors in the Cat Dorsal Horn  Academic Article
• Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret  Academic Article
• Enantioselective Organocatalytic Michael/Aldol Sequence: Anticancer Natural Product (+)-trans-Dihydrolycoricidine  Academic Article
• Enantioselective Synthesis of Planar Chiral Ferrocifens that Show Chiral Discrimination in Antiproliferative Activity on Breast Cancer Cells  Academic Article
• Flexibility of “Polyunsaturated Fatty Acid Chains” and Peptide Backbones:  A Comparative ab Initio Study  Academic Article
• General method for the determination of precursor configuration in biosynthetic precursor-product relations. Derivation of pipecolic acid from D-lysine, and of piperidine alkaloids from L-lysine  Academic Article
• Guaianolides from Salvia nubicola (Lamiaceae)  Academic Article
• High quality drug screening by capillary electrophoresis: A review  Academic Article
• Homoserine dehydrogenase from Saccharomyces cerevisiae: kinetic mechanism and stereochemistry of hydride transfer  Academic Article
• Human Cytochrome P450 Liability Studies of trans-Dihydronarciclasine: A Readily Available, Potent, and Selective Cancer Cell Growth Inhibitor  Academic Article
• Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle  Academic Article
• Implication of a Nitric Oxide Synthase Mechanism in the Action of Substance P: L-NAME Blocks Thermal Hyperalgesia Induced by Endogenous and Exogenous Substance P in the Rat  Academic Article
• Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase)  Academic Article
• Involvement of nitric oxide in nerve-mediated inhibition and action of vasoactive intestinal peptide in colonic smooth muscle.  Academic Article
• Lactate transport by rainbow trout white muscle: kinetic characteristics and sensitivity to inhibitors  Academic Article
• Metal-Induced Isomerization Yields an Intracellular Chelator that Disrupts Bacterial Iron Homeostasis  Academic Article
• Molecular Mechanism for the (−)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers  Academic Article
• Molecular mechanism of VanHst, an alpha-ketoacid dehydrogenase required for glycopeptide antibiotic resistance from a glycopeptide producing organism  Academic Article
• Muscarinic cholonoceptors in the rabbits myometrium: A study of the relationship between binding and response  Academic Article
• Neuroimaging of mirtazapine enantiomers in humans  Academic Article
• New Advances in Amino Acid Profiling in Biological Samples by Capillary Electrophoresis-Mass Spectrometry  Academic Article
• On the Pharmacological and Physiological Role of Glibenclamide-Sensitive Potassium Channels in Colonic Smooth Muscle  Academic Article
• On the Role of Chirality in Guiding the Self-Assembly of Peptides  Academic Article
• On-line sample preconcentration with chemical derivatization of bacterial biomarkers by capillary electrophoresis: A dual strategy for integrating sample pretreatment with chemical analysis  Academic Article
• Oxaprotiline: Induction of central noradrenergic subsensitivity by its (+)-enantiomer  Academic Article
• Phaclofen-reversible effects of GABA in the spinal cord of the rat  Academic Article
• Photoinduced Intramolecular Macrocyclization Reaction between a Bpa and a Met Residue in a Helical Peptide: 3D Structures of the Diastereomeric Products  Academic Article
• Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives  Academic Article
• Preparation and Evaluation of Carborane Analogues of Tamoxifen  Academic Article
• Preparation of Enantiomerically Purel-7-Azatryptophan by an Enzymatic Method and Its Application to the Development of a Fluorimetric Activity Assay for Tryptophanyl-tRNA Synthetase  Academic Article
• Review of the use of mirtazapine in the treatment of depression  Academic Article
• Sample preconcentration with chemical derivatization in capillary electrophoresis  Academic Article
• Silanones and Silanethiones from the Reactions of Transient Silylenes with Oxiranes and Thiiranes in Solution. The Direct Detection of Diphenylsilanethione.  Academic Article
• Single-step enantioselective amino acid flux analysis by capillary electrophoresis using on-line sample preconcentration with chemical derivatization  Academic Article
• Stereospecific binding sites for [3H]nicotinamide adenine dinucleotide in the rat brain  Academic Article
• Stoichiometrically controlled production of bimetallic Gold-Silver alloy colloids using micro-alga cultures  Academic Article
• Strategies and Synthetic Methods Directed Toward the Preparation of Libraries of Substituted Isoquinolines  Academic Article
• Structural requirements for specific inhibition of microsomal aminopeptidase by mercaptoamines  Academic Article
• Substrate Chirality and Specificity of Diacylglycerol Kinases and the Multisubstrate Lipid Kinase  Academic Article
• Synthesis and Biological Evaluation of Fully Functionalized seco-Pancratistatin Analogues  Academic Article
• Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation  Academic Article
• Synthesis and Screening of a Library of Re/Tc-Based Amyloid Probes Derived from β-Breaker Peptides  Academic Article
• Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide  Academic Article
• Synthesis and Structure−Activity Relationships of Truncated Bisubstrate Inhibitors of Aminoglycoside 6‘-N-Acetyltransferases  Academic Article
• Synthesis and inhibitory action on HMG-CoA synthase of racemic and optically active oxetan-2-ones (β-Lactones)  Academic Article
• Synthesis of Boroxifen, A Nido-Carborane Analogue of Tamoxifen  Academic Article
• Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol  Academic Article
• The ??2-Agonist Controversy  Academic Article
• The Chirality of Phosphatidylserine and the Activation of Protein Kinase C  Academic Article
• The Effect of Food or Sucralfate on the Bioavailability of S(+) and R(−) Enantiomers of Ibuprofen  Academic Article
• The helix-coil transition of poly-L-lysine in methanol-water solvent mixtures  Academic Article
• The nonpeptide NK-1 receptor antagonists LY303870 and LY306740 block the responses of spinal dorsal horn neurons to substance P and to peripheral noxious stimuli  Academic Article
• The regiochemistry and stereochemistry of the biosynthesis of vitamin B6 from triose units.  Academic Article
• Total Synthesis of (+)-Angelmarin  Academic Article
• Total Synthesis of (±)-Mersicarpine  Academic Article
• Two-step regio- and stereoselective syntheses of [19F]- and [18F]-2-deoxy-2-(R)-fluoro-β-d-allose  Academic Article
• Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?  Academic Article
• [Structure of collagen with a new net of hydrogen bonds].  Academic Article
• [Topography of the active site of the noradrenaline neuronal membrane carrier based on the theoretical conformation analysis of inhibitors of neuronal catecholamine uptake].  Academic Article