Stereoisomerism
Concept
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Overview
subject area of
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A Stereoselective Hydroxylation Step of Alkaloid Biosynthesis by a Unique Cytochrome P450 in Catharanthus roseus Academic Article
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A Versatile Endoribonuclease Mimic Made of DNA: Characteristics and Applications of the 8-17 RNA-Cleaving DNAzyme Academic Article
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A proposal for an extended dual descriptor: a possible solution when Frontier Molecular Orbital Theory fails Academic Article
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A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents Academic Article
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A sensitive signal-on electrochemiluminescence sensor based on a nanocomposite of polypyrrole-Gd2O3 for the determination of L-cysteine in biological fluids Academic Article
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Allosteric Modulation of the Dopamine D2 Receptor by Pro-Leu-Gly-NH2 Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II β-Turn Conformation Academic Article
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Allosteric Modulation of the Dopamine Receptor by Conformationally Constrained Type VI β-Turn Peptidomimetics of Pro-Leu-Gly-NH2 Academic Article
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Altered levels of antithrombin III and fibrinogen in the aortic wall of the alloxan-induced diabetic rabbit: evidence of a prothrombotic state. Academic Article
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Amino Acid Racemization and the Preservation of Ancient DNA Academic Article
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Amino acid racemization in amber-entombed insects: Implications for DNA preservation Academic Article
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Autocatalytic Replication and Homochirality in Biopolymers: Is Homochirality a Requirement of Life or a Result of It? Academic Article
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Biosynthesis of the piperidine nucleus. Incorporation of chirally labeled cadaverine-1-3H Academic Article
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CP-96,345, but not its stereoisomer, CP-96,344, blocks the nociceptive responses to intrathecally administered substance P and to noxious thermal and chemical stimuli in the rat Academic Article
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Cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat Academic Article
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Chimeric Streptogramin-Tyrocidine Antibiotics that Overcome Streptogramin Resistance Academic Article
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Chirality in antirheumatic drugs Academic Article
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Circular dichroism (CD) studies of antagonists derived from parathyroid hormone-related protein Academic Article
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Collagen-Based Structures Containing the Peptoid Residue N-Isobutylglycine (Nleu): Conformational Analysis of Gly-Nleu-Pro Sequences by 1H-NMR and Molecular Modeling Academic Article
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Comprehensive Radiolabeling, Stability, and Tissue Distribution Studies of Technetium-99m Single Amino Acid Chelates (SAAC) Academic Article
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Conformations of poly-L-valine in solution Academic Article
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Contractile activity in intestinal muscle evokes action potential discharge in guinea‐pig myenteric neurons Academic Article
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Crystal structure of cGMP‐dependent protein kinase Iβ cyclic nucleotide‐binding‐B domain : Rp‐cGMPS complex reveals an apo‐like, inactive conformation Academic Article
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Cyclopolymerization Reactions of Diallyl Monomers: Exploring Electronic and Steric Effects Using DFT Reactivity Indices Academic Article
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Diels-Alder Additions as Mechanistic Probes–Interception of Silyl-Isoindenes: Organometallic Derivatives of Polyphenylated Cycloheptatrienes and Related Seven-Membered Rings Academic Article
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Differential Toxicity of Cis andTrans Isomers of Dichlorodiammineplatinum Academic Article
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Directed Remote Aromatic Metalations: Mechanisms and Driving Forces Academic Article
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Does the left hand know what the right hand is doing? or Clinical pharmacology: the use of optically pure (R or S) forms of chiral drugs rather than racemic mixtures. Academic Article
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Effect of R and S Enantiomers of Naproxen on Aggregation and Thromboxane Production in Human Platelets Academic Article
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Effects of intravenously administered enantiomers of baclofen on functionally identified units in lumbar dorsal horn of the spinal cat Academic Article
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Effects of phaclofen and the enantiomers of baclofen on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat Academic Article
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Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation Academic Article
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Electrophoretic deposition of TiO2 and composite TiO2–MnO2 films using benzoic acid and phenolic molecules as charging additives Academic Article
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Electrophysiological Evidence That Neurokinin A Acts Via NK-1 Receptors in the Cat Dorsal Horn Academic Article
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Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret Academic Article
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Enantioselective Organocatalytic Michael/Aldol Sequence: Anticancer Natural Product (+)-trans-Dihydrolycoricidine Academic Article
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Enantioselective Synthesis of Planar Chiral Ferrocifens that Show Chiral Discrimination in Antiproliferative Activity on Breast Cancer Cells Academic Article
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Flexibility of “Polyunsaturated Fatty Acid Chains” and Peptide Backbones: A Comparative ab Initio Study Academic Article
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General method for the determination of precursor configuration in biosynthetic precursor-product relations. Derivation of pipecolic acid from D-lysine, and of piperidine alkaloids from L-lysine Academic Article
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Guaianolides from Salvia nubicola (Lamiaceae) Academic Article
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High quality drug screening by capillary electrophoresis: A review Academic Article
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Homoserine dehydrogenase from Saccharomyces cerevisiae: kinetic mechanism and stereochemistry of hydride transfer Academic Article
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Human Cytochrome P450 Liability Studies of trans-Dihydronarciclasine: A Readily Available, Potent, and Selective Cancer Cell Growth Inhibitor Academic Article
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Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle Academic Article
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Implication of a Nitric Oxide Synthase Mechanism in the Action of Substance P: L-NAME Blocks Thermal Hyperalgesia Induced by Endogenous and Exogenous Substance P in the Rat Academic Article
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Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase) Academic Article
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Involvement of nitric oxide in nerve-mediated inhibition and action of vasoactive intestinal peptide in colonic smooth muscle. Academic Article
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Lactate transport by rainbow trout white muscle: kinetic characteristics and sensitivity to inhibitors Academic Article
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Metal-Induced Isomerization Yields an Intracellular Chelator that Disrupts Bacterial Iron Homeostasis Academic Article
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Molecular Mechanism for the (−)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers Academic Article
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Molecular mechanism of VanHst, an alpha-ketoacid dehydrogenase required for glycopeptide antibiotic resistance from a glycopeptide producing organism Academic Article
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Muscarinic cholonoceptors in the rabbits myometrium: A study of the relationship between binding and response Academic Article
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Neuroimaging of mirtazapine enantiomers in humans Academic Article
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New Advances in Amino Acid Profiling in Biological Samples by Capillary Electrophoresis-Mass Spectrometry Academic Article
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On the Pharmacological and Physiological Role of Glibenclamide-Sensitive Potassium Channels in Colonic Smooth Muscle Academic Article
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On the Role of Chirality in Guiding the Self-Assembly of Peptides Academic Article
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On-line sample preconcentration with chemical derivatization of bacterial biomarkers by capillary electrophoresis: A dual strategy for integrating sample pretreatment with chemical analysis Academic Article
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Oxaprotiline: Induction of central noradrenergic subsensitivity by its (+)-enantiomer Academic Article
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Phaclofen-reversible effects of GABA in the spinal cord of the rat Academic Article
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Photoinduced Intramolecular Macrocyclization Reaction between a Bpa and a Met Residue in a Helical Peptide: 3D Structures of the Diastereomeric Products Academic Article
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Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives Academic Article
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Preparation and Evaluation of Carborane Analogues of Tamoxifen Academic Article
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Preparation of Enantiomerically Purel-7-Azatryptophan by an Enzymatic Method and Its Application to the Development of a Fluorimetric Activity Assay for Tryptophanyl-tRNA Synthetase Academic Article
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Review of the use of mirtazapine in the treatment of depression Academic Article
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Sample preconcentration with chemical derivatization in capillary electrophoresis Academic Article
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Silanones and Silanethiones from the Reactions of Transient Silylenes with Oxiranes and Thiiranes in Solution. The Direct Detection of Diphenylsilanethione. Academic Article
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Single-step enantioselective amino acid flux analysis by capillary electrophoresis using on-line sample preconcentration with chemical derivatization Academic Article
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Stereospecific binding sites for [3H]nicotinamide adenine dinucleotide in the rat brain Academic Article
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Stoichiometrically controlled production of bimetallic Gold-Silver alloy colloids using micro-alga cultures Academic Article
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Strategies and Synthetic Methods Directed Toward the Preparation of Libraries of Substituted Isoquinolines Academic Article
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Structural requirements for specific inhibition of microsomal aminopeptidase by mercaptoamines Academic Article
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Substrate Chirality and Specificity of Diacylglycerol Kinases and the Multisubstrate Lipid Kinase Academic Article
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Synthesis and Biological Evaluation of Fully Functionalized seco-Pancratistatin Analogues Academic Article
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Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation Academic Article
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Synthesis and Screening of a Library of Re/Tc-Based Amyloid Probes Derived from β-Breaker Peptides Academic Article
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Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide Academic Article
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Synthesis and Structure−Activity Relationships of Truncated Bisubstrate Inhibitors of Aminoglycoside 6‘-N-Acetyltransferases Academic Article
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Synthesis and inhibitory action on HMG-CoA synthase of racemic and optically active oxetan-2-ones (β-Lactones) Academic Article
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Synthesis of Boroxifen, A Nido-Carborane Analogue of Tamoxifen Academic Article
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Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol Academic Article
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The ??2-Agonist Controversy Academic Article
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The Chirality of Phosphatidylserine and the Activation of Protein Kinase C Academic Article
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The Effect of Food or Sucralfate on the Bioavailability of S(+) and R(−) Enantiomers of Ibuprofen Academic Article
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The helix-coil transition of poly-L-lysine in methanol-water solvent mixtures Academic Article
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The nonpeptide NK-1 receptor antagonists LY303870 and LY306740 block the responses of spinal dorsal horn neurons to substance P and to peripheral noxious stimuli Academic Article
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The regiochemistry and stereochemistry of the biosynthesis of vitamin B6 from triose units. Academic Article
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Total Synthesis of (+)-Angelmarin Academic Article
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Total Synthesis of (±)-Mersicarpine Academic Article
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Two-step regio- and stereoselective syntheses of [19F]- and [18F]-2-deoxy-2-(R)-fluoro-β-d-allose Academic Article
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Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil? Academic Article
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[Structure of collagen with a new net of hydrogen bonds]. Academic Article
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[Topography of the active site of the noradrenaline neuronal membrane carrier based on the theoretical conformation analysis of inhibitors of neuronal catecholamine uptake]. Academic Article