Microtermolides A and B from Termite-Associated Streptomyces sp. and Structural Revision of Vinylamycin Journal Articles uri icon

  •  
  • Overview
  •  
  • Research
  •  
  • Identity
  •  
  • Additional Document Info
  •  
  • View All
  •  

abstract

  • Microtermolides A (1) and B (2) were isolated from a Streptomyces sp. strain associated with fungus-growing termites. The structures of 1 and 2 were determined by 1D- and 2D-NMR spectroscopy and high-resolution mass spectrometry. Structural elucidation of 1 led to the re-examination of the structure originally proposed for vinylamycin (3). Based on a comparison of predicted and experimental (1)H and (13)C NMR chemical shifts, we propose that vinylamycin's structure be revised from 3 to 4.

authors

  • Carr, Gavin
  • Poulsen, Michael
  • Klassen, Jonathan L
  • Hou, Yanpeng
  • Wyche, Thomas P
  • Bugni, Tim S
  • Currie, Cameron
  • Clardy, Jon

publication date

  • June 1, 2012