Cell Line, Transformed Concept

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• A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death  Academic Article
• A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns  Academic Article
• Adenovirus Vector Expressing Mouse Oncostatin M Induces Acute-Phase Proteins and TIMP-1 Expression In Vivo in Mice  Academic Article
• Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis  Academic Article
• At the onset of transformation polyomavirus middle-T recruits shc and src to a perinuclear compartment coincident with condensation of endosomes  Academic Article
• Bystander effects induced by serum from survivors of the Chernobyl accident  Academic Article
• Chronic nicotine induces hypoxia inducible factor-2α in perinatal rat adrenal chromaffin cells: role in transcriptional upregulation of KATP channel subunit Kir6.2  Academic Article
• Cloning and Sequencing of the Cellular–Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line  Academic Article
• Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy  Academic Article
• Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity  Academic Article
• Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors.  Academic Article
• Delayed cell death and bystander effects in the progeny of Chinook Salmon Embryo cells exposed to radiation and a range of aquatic pollutants  Academic Article
• Determining MHC Restriction of T-cell Responses  Academic Article
• Development and characterization of a binary gene expression system based on bacteriophage T7 components in adenovirus vectors  Academic Article
• Development of the ?Cell Chip?: a new in vitro alternative technique for immunotoxicity testing  Academic Article
• Dramatic Differences in the Roles in Lipid Metabolism of Two Isoforms of Diacylglycerol Kinase†  Academic Article
• ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53  Academic Article
• Early host cell reactivation of an oxidatively damaged adenovirus-encoded reporter gene requires the Cockayne syndrome proteins CSA and CSB  Academic Article
• Effects of peroxynitrite on sarco/endoplasmic reticulum Ca2+ pump isoforms SERCA2b and SERCA3a  Academic Article
• Enhanced Interleukin-2 Gene Transfer Immunotherapy of Breast Cancer by Coexpression of B7-1 and B7-2  Academic Article
• Evidence for the transmission of neoplastic properties from transformed to normal human stem cells  Academic Article
• Expression of Lethal Mutations Is Suppressed in Neoplastically Transformed Cells and after Treatment of Normal Cells with Carcinogens  Academic Article
• Expression of the beta 4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells  Academic Article
• Extracellular glutamate alters mature osteoclast and osteoblast functions  Academic Article
• Factor VII deficiency caused by a structural variant N57D of the first epidermal growth factor domain.  Academic Article
• Glucosensing in an immortalized adrenomedullary chromaffin cell line: Role of ATP-sensitive K+ channels  Academic Article
• Heat-shock enhanced reactivation of a UV-damaged reporter gene in human cells involves the transcription coupled DNA repair pathway  Academic Article
• Histone Modification Profiling in Normal and Transformed Human Embryonic Stem Cells Using Micro Chromatin Immunoprecipitation, Scalable to Genome-Wide Microarray Analyses  Academic Article
• Hypoxia inducible factor (HIF)-2α is required for the development of the catecholaminergic phenotype of sympathoadrenal cells  Academic Article
• Identification and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A)+RNA Binding Protein  Academic Article
• Identification of ataxia-associated mtDNA mutations (m.4052T>C and m.9035T>C) and evaluation of their pathogenicity in transmitochondrial cybrids  Academic Article
• Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors  Academic Article
• Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds  Academic Article
• Immunoglobulin E mediated membrane conductance changes in rat basophilic leukemia cells  Academic Article
• Impact of Multipurpose Solutions Released from Contact Lenses on Corneal Cells  Academic Article
• Incomplete complementation of the DNA repair defect in cockayne syndrome cells by the denV gene from bacteriophage T4 suggests a deficiency in base excision repair  Academic Article
• Induced pluripotent stem cell–based mapping of β-globin expression throughout human erythropoietic development  Academic Article
• Induction of genomic instability in SV40 transformed human cells: sufficiency of the N-terminal 147 amino acids of large T antigen and role of pRB and p53.  Academic Article
• Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation  Academic Article
• Interactions of corneal epithelial cells and surfaces modified with cell adhesion peptide combinations  Academic Article
• Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression  Academic Article
• Intracellular distribution of DNA internalized through calcium phosphate precipitation  Academic Article
• Lifeact cannot visualize some forms of stress-induced twisted f-actin  Academic Article
• Mechanisms of cytosolic targeting of matrix metalloproteinase-2  Academic Article
• Micronuclei formation in rainbow trout cells exposed to multiple stressors: Morpholine, heat shock, and ionizing radiation  Academic Article
• Modulation of Monocyte Function by Activated Protein C, a Natural Anticoagulant  Academic Article
• N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation  Academic Article
• Neuroprotective effects of guanosine on stroke models in vitro and in vivo  Academic Article
• Nucleotide sequences of an antiidiotypic antibody from a transplant recipient  Academic Article
• O2−sensitive K+channels in immortalised rat chromaffin-cell-derived MAH cells  Academic Article
• O6-Ethylguanine and O6-benzylguanine incorporated site-specifically in codon 12 of the rat H-ras gene induce semi-targeted as well as targeted mutations in Rat4 cells  Academic Article
• Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells  Academic Article
• Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis  Academic Article
• Pleiotropic Action of AP-1 in v-Src-Transformed Cells  Academic Article
• Pluripotent Transcription Factors Possess Distinct Roles in Normal versus Transformed Human Stem Cells  Academic Article
• Postirradiation Expression of Lethal Mutations in an Immortalized Human Keratinocyte Cell Line  Academic Article
• Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells  Academic Article
• Rapid Insulin-like Growth Factor-1-induced Changes in Granulosa Cell Thrombospondin-1 Expression In Vitro  Academic Article
• Ras-GTP levels are elevated in human NF1 peripheral nerve tumors.  Academic Article
• Reconstitution of Wild-Type or Mutant Telomerase Activity in Telomerase-Negative Immortal Human Cells  Academic Article
• Relative contribution of bystander and targeted cell killing to the low-dose region of the radiation dose-response curve.  Academic Article
• Scavenging of Extracellular H2O2by Catalase Inhibits the Proliferation of HER-2/Neu-transformed Rat-1 Fibroblasts through the Induction of a Stress Response  Academic Article
• Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes.  Academic Article
• TLR5 as an Anti-Inflammatory Target and Modifier Gene in Cystic Fibrosis  Academic Article
• Telomerase activity associated with acquisition of malignancy in human colorectal cancer.  Academic Article
• Telomere elongation in immortal human cells without detectable telomerase activity.  Academic Article
• The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm  Academic Article
• The Role of the p53 Tumor Suppressor in the Response of Human Cells to Photofrin-mediated Photodynamic Therapy  Academic Article
• The Telomere Lengthening Mechanism in Telomerase-Negative Immortal Human Cells Does Not Involve the Telomerase RNA Subunit  Academic Article
• The effect of E1 mutations on biochemical transformation by an adenovirus carrying the herpes simplex virus thymidine kinase gene in region E3  Academic Article
• The effect of microcolony size, at time of irradiation, on colony forming ability  Academic Article
• The first exon of Ad12 E1A excluding the transactivation domain mediates differential binding of COUP-TF and NF-kappa B to the MHC class I enhancer in transformed cells.  Academic Article
• The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus  Academic Article
• The thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis  Academic Article
• Transient Expression of Wild-Type or Biologically Inactive Telomerase Allows the Formation of Artificial Telomeres in Mortal Human Cells  Academic Article
• Tumorigenicity of adenovirus-transformed rodent cells is influenced by at least two regions of adenovirus type 12 early region 1A.  Academic Article
• UV-enhanced Expression of a Reporter Gene is Induced at Lower UV Fluences in Transcription-coupled Repair Deficient Compared to Normal Human Fibroblasts, and is Absent in SV40-transformed Counterparts¶  Academic Article
• v-Src inhibits myogenic differentiation by interfering with the regulatory network of muscle-specific transcriptional activators at multiple levels  Academic Article