Journal article
Postirradiation Expression of Lethal Mutations in an Immortalized Human Keratinocyte Cell Line
Abstract
The quantification of the extent of delayed cell death and the rate and pattern of its occurrence in relation to the cell division cycle is important in radiotherapy and also in radiation transformation studies related to protection and dose limits. Here the numbers of lethal mutations occurring over 45 population doublings (clonal expansion to about 10(13) cells per cell originally surviving irradiation) was measured in an HPV 16 immortalized …
Authors
O'Reilly S; Mothersill C; Seymour CB
Journal
International Journal of Radiation Biology, Vol. 66, No. 1, pp. 77–83
Publisher
Taylor & Francis
Publication Date
1 1994
DOI
10.1080/09553009414550961
ISSN
0955-3002