Induced pluripotent stem cell–based mapping of β-globin expression throughout human erythropoietic development Academic Article uri icon

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abstract

  • Key Points iPSC-derived definitive erythroid cells display a globin expression profile corresponding to yolk sac erythromyeloid progenitors. iPSC-derived erythroblasts resemble their postnatal counterparts in terms of gene expression and essential biological processes.

authors

  • Vanuytsel, Kim
  • Matte, Taylor
  • Leung, Amy
  • Naing, Zaw Htut
  • Morrison, Tasha
  • Chui, David Hing-kwei
  • Steinberg, Martin H
  • Murphy, George J

publication date

  • August 14, 2018