selected scholarly activity
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conferences
- Statistical considerations for analyzing multiplex biomarker data from prospective studies. Trials. 2017
- The prevalence of preoperative elevations in troponin T above the 99th percentile using the troponin T high sensitive assay in patients undergoing noncardiac surgery. Clinical Biochemistry. 1174-1174. 2011
- Strategy of intensive glycemic control with pioglitazone does not significantly reduce in-stent neointimal volume after percutaneous coronary intervention in type 2 diabetic patients. Circulation. 470-470. 2007
- A strategy of intensive glycemic control with pioglitazone does not significantly reduce instent neointimal volume after percutaneous coronary intervention in type 2 diabetic patients. Canadian Journal of Cardiology. 78C-78C. 2007
- Variation in troponin T in stable outpatient hemodialysis patients. Clinical Biochemistry. 1101-1101. 2006
- Comparative impact of multiple biomarkers and N-terminal pro-brain natriuretic peptide in the context of conventional risk factors for the prediction of recurrent cardiovascular events in the heart outcomes prevention evaluation (HOPE) Study. Circulation. 871-871. 2006
- Baseline high-sensitivity C-reactive protein offers prognostic value in addition to contemporary risk stratification in non-ST-segment elevation acute coronary syndrome: Results from the CURE inflammatory marker substudy. Circulation. 499-499. 2004
- Folic acid improves endothelial dysfunction in type 2 diabetes, an effect independent of homocysteine lowering. Circulation. 332-332. 2004
- Applying proteomics to characterize the plasma protein profile correlating to hyperhomocysteinemia: Linking genomics and proteomics.. Clinical Chemistry. A38-A38. 2001
- The Stockholm Consensus Conference on Quality Specifications in Laboratory Medicine, 25-26 April 1999. Scandinavian Journal of Clinical and Laboratory Investigation. 475-475. 1999
- Blood lipid profiles in children with acute lymphoblastic leukemia. Cancer. 379-384. 1998
- Hyperhomocysteinemia and mutations in methylene tetrahydrofolate reductase in individuals with early coronary artery disease.. Clinical Chemistry. A165-A165. 1998
- Development of an etching technique for bleached enamel.. Journal of Dental Research. 935-935. 1997
- Mutation frequencies of cholesterol ester transfer protein (CETP) and hepatic lipase (HL) in a north American population.. Clinical Chemistry. 841-841. 1996
- Proficiency testing of hemoglobin A1c (HbA1c) in the province of Ontario, Canada.. Clinical Chemistry. 752-752. 1996
- Proficiency testing of hemoglobin A1c (HbA1c) in the province of Ontario, Canada.. Clinical Chemistry. 751-751. 1996
- THEORY AND PRACTICE OF QUALITY ASSURANCE IN CARDIOVASCULAR MEDICINE. CANADIAN JOURNAL OF CARDIOLOGY, VOL 9, SUPPLEMENT D, MAY 1993. D92-D93. 1993
- RATIONALIZATION OF HOSPITAL, UNIVERSITY AND COMMUNITY LABORATORY SERVICES - THE HAMILTON HEALTH-SCIENCES LABORATORY PROGRAM. International Congress Series. 9-12. 1992
- DETECTION OF ISCHEMIC MYOCARDIAL INJURY IN PATIENTS WITH NORMAL OR SLIGHT ELEVATIONS IN, CK AND ASAT ACTIVITIES. Clinical Biochemistry. P4-P4. 1981
- BIOCHEMICAL AND CLINICAL DIAGNOSIS OF MYOCARDIAL-INFARCTION. Clinical Biochemistry. P11-P11. 1977
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journal articles
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Determinants of serious health
outcome‐free status inmiddle‐aged and older people with dysglycaemia: Exploratory analysis of theORIGIN trial. Diabetes, Obesity and Metabolism. 26:3272-3280. 2024 - Tobacco use and risk of acute stroke in 32 countries in the INTERSTROKE study: a case–control study. EClinicalMedicine. 70:102515-102515. 2024
- The Clinical Validation of a Common Analytical Change Criteria for Cardiac Troponin for Ruling in an Acute Cardiovascular Outcome in Patients Presenting with Ischemic Chest Pain Symptoms. Journal of Cardiovascular Development and Disease. 10:335-335. 2023
- Effects of routine early treatment with PCSK9 inhibitors in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: a randomised, double-blind, sham-controlled trial . EuroIntervention. 18:e888-e896. 2022
- Association of Lipids, Lipoproteins, and Apolipoproteins with Stroke Subtypes in an International Case Control Study (INTERSTROKE). Journal of Stroke. 24:224-235. 2022
- Biomarkers of Prevalent and Incident Cognitive Dysfunction in People with Dysglycemia: Data from the ORIGIN Trial. Journal of Alzheimer's Disease. 87:1143-1150. 2022
- High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality. New England Journal of Medicine. 386:827-836. 2022
- Diagnostic Performance of Serial High-Sensitivity Cardiac Troponin Measurements in the Emergency Setting. Journal of Cardiovascular Development and Disease. 8:97-97. 2021
- NT-proBNP versus routine clinical risk factors as a predictor of cardiovascular events or death in people with dysglycemia – A brief report from the ORIGIN trial. Journal of Diabetes and its Complications. 35:107928-107928. 2021
- Comparison of two biomarker only algorithms for early risk stratification in patients with suspected acute coronary syndrome. International Journal of Cardiology. 319:140-143. 2020
- Using the clinical chemistry score in the emergency department to detect adverse cardiac events: a diagnostic accuracy study. CMAJ open. 8:E676-E684. 2020
- Clinical evaluation of Ortho Clinical Diagnostics high-sensitivity cardiac Troponin I assay in patients with symptoms suggestive of acute coronary syndrome. Clinical Biochemistry. 80:48-51. 2020
- Association Between Myocardial Injury and Cardiovascular Outcomes of Orthopaedic Surgery. Journal of Bone and Joint Surgery. American volume. 102:880-888. 2020
- Novel Biomarkers for Change in Renal Function in People With Dysglycemia. Diabetes Care. 43:433-439. 2020
- Preoperative N-Terminal Pro–B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery. ACP journal club. 172:96-96. 2020
- Lipoprotein(a) Levels and the Risk of Myocardial Infarction Among 7 Ethnic Groups. Circulation. 139:1472-1482. 2019
- Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study. The BMJ. 364:l772-l772. 2019
- A Mendelian Randomization-Based Approach to Identify Early and Sensitive Diagnostic Biomarkers of Disease. Clinical Chemistry. 65:427-436. 2019
- The association of basal insulin treatment versus standard care with outcomes in anti‐GAD positive and negative subjects: A post‐hoc analysis of the ORIGIN trial. Diabetes, Obesity and Metabolism. 21:429-433. 2019
- A failure of standardization or a failure of the process of standardization. Journal of Clinical Lipidology. 12:1325-1326. 2018
- High-sensitivity cardiac troponin concentrations at emergency department presentation in females and males with an acute cardiac outcome. Annals of Clinical Biochemistry. 55:604-607. 2018
- Clinical chemistry score versus high-sensitivity cardiac troponin I and T tests alone to identify patients at low or high risk for myocardial infarction or death at presentation to the emergency department. CANADIAN MEDICAL ASSOCIATION JOURNAL. 190:E974-E984. 2018
- Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study. The Lancet. 392:496-506. 2018
- Practice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study. The Lancet. 391:2019-2027. 2018
- Performance of high-sensitivity cardiac troponin in the emergency department for myocardial infarction and a composite cardiac outcome across different estimated glomerular filtration rates. Clinica Chimica Acta. 479:166-170. 2018
- Classification rules for identifying individuals at high risk of developing myocardial infarction based on ApoB, ApoA1 and the ratio were determined using a Bayesian approach. Journal of Applied Statistics. 45:210-224. 2018
- Association of Apolipoproteins B and A-1 With Markers of Vascular Health or Cardiovascular Events. Canadian Journal of Cardiology. 33:1305-1311. 2017
- Association of dietary nutrients with blood lipids and blood pressure in 18 countries: a cross-sectional analysis from the PURE study. The Lancet Diabetes and Endocrinology. 5:774-787. 2017
- Availability and affordability of blood pressure-lowering medicines and the effect on blood pressure control in high-income, middle-income, and low-income countries: an analysis of the PURE study data. The Lancet Public Health. 2:e411-e419. 2017
- STARD for Abstracts: essential items for reporting diagnostic accuracy studies in journal or conference abstracts. The BMJ. 358:j3751-j3751. 2017
- High-Sensitivity Cardiac Troponin Risk Cutoffs for Acute Cardiac Outcomes at Emergency Department Presentation. Canadian Journal of Cardiology. 33:898-903. 2017
- Validation of the ORIGIN Cardiovascular Biomarker Panel and the Value of Adding Troponin I in Dysglycemic People. Journal of Clinical Endocrinology and Metabolism (JCEM). 102:2251-2257. 2017
- A laboratory score at presentation to rule-out serious cardiac outcomes or death in patients presenting with symptoms suggestive of acute coronary syndrome. Clinica Chimica Acta. 469:69-74. 2017
- Validation of a Capillary Electrophoresis Assay for Monitoring Iodine Nutrition in Populations for Prevention of Iodine Deficiency: An Interlaboratory Method Comparison. The journal of applied laboratory medicine. 1:649-660. 2017
- Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery. Journal of the American Medical Association (JAMA). 317:1642-1642. 2017
- Economic Considerations of Early Rule-In/Rule-Out Algorithms for The Diagnosis of Myocardial Infarction in The Emergency Department Using Cardiac Troponin and Glycemic Biomarkers. Clinical Chemistry. 63:593-602. 2017
- Growth Differentiation Factor 15 as a Novel Biomarker for Metformin. Diabetes Care. 40:280-283. 2017
- Rule-In and Rule-Out of Myocardial Infarction Using Cardiac Troponin and Glycemic Biomarkers in Patients with Symptoms Suggestive of Acute Coronary Syndrome. Clinical Chemistry. 63:403-414. 2017
- Age and Cardiovascular Risk Attributable to Apolipoprotein B, Low‐Density Lipoprotein Cholesterol or Non‐High‐Density Lipoprotein Cholesterol. Journal of the American Heart Association. 5:e003665. 2016
- Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study. The Lancet. 388:761-775. 2016
- Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. The Lancet. 388:465-475. 2016
- Cardiovascular and Other Outcomes Postintervention With Insulin Glargine and Omega-3 Fatty Acids (ORIGINALE). Diabetes Care. 39:709-716. 2016
- Variations in Diabetes Prevalence in Low-, Middle-, and High-Income Countries: Results From the Prospective Urban and Rural Epidemiological Study. Diabetes Care. 39:780-787. 2016
- Telomere Length and Risk of Myocardial Infarction in a MultiEthnic Population. Journal of the American College of Cardiology. 67:1863-1865. 2016
- Assessment of Dietary Sodium and Potassium in Canadians Using 24-Hour Urinary Collection. Canadian Journal of Cardiology. 32:319-326. 2016
- Identifying Novel Biomarkers for Cardiovascular Events or Death in People With Dysglycemia. Circulation. 132:2297-2304. 2015
- STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies. Clinical Chemistry. 61:1446-1452. 2015
- Association of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) With Cardiovascular Risk in Primary Prevention. Arteriosclerosis, Thrombosis and Vascular Biology. 35:2254-2259. 2015
- The Relationship Between Trimethylamine-N-Oxide and Prevalent Cardiovascular Disease in a Multiethnic Population Living in Canada. Canadian Journal of Cardiology. 31:1189-1194. 2015
- Genome-wide studies to identify risk factors for kidney disease with a focus on patients with diabetes. Nephrology Dialysis Transplantation. 30:iv26-iv34. 2015
- Elevated cholesteryl ester transfer protein (CETP) activity, a major determinant of the atherogenic dyslipidemia, and atherosclerotic cardiovascular disease in South Asians. European Journal of Preventive Cardiology (EJPC). 22:468-477. 2015
- Variability of ethics education in laboratory medicine training programs: Results of an international survey. Clinica Chimica Acta. 442:115-118. 2015
- The Preventive Potential of Common, Easily Measured Risk Factors for Cardiovascular Disease. Clinical Chemistry. 60:1450-1451. 2014
- A Robust Method for Iodine Status Determination in Epidemiological Studies by Capillary Electrophoresis. Analytical Chemistry. 86:10010-10015. 2014
- Mortality and morbidity in relation to changes in albuminuria, glucose status and systolic blood pressure: an analysis of the ONTARGET and TRANSCEND studies. Diabetologia. 57:2019-2029. 2014
- Validation and comparison of three formulae to estimate sodium and potassium excretion from a single morning fasting urine compared to 24-h measures in 11 countries (vol 32, pg 1005, 2014). Journal of Hypertension. 32:1915-1915. 2014
- Cardiovascular Risk and Events in 17 Low-, Middle-, and High-Income Countries. New England Journal of Medicine. 371:818-827. 2014
- Association of Urinary Sodium and Potassium Excretion with Blood Pressure. New England Journal of Medicine. 371:601-611. 2014
- Urinary Sodium and Potassium Excretion, Mortality, and Cardiovascular Events. New England Journal of Medicine. 371:612-623. 2014
- Validation and comparison of three formulae to estimate sodium and potassium excretion from a single morning fasting urine compared to 24-h measures in 11 countries. Journal of Hypertension. 32:1005-1015. 2014
- Myocardial Injury after Noncardiac Surgery. Anesthesiology. 120:564-578. 2014
- State of the Art for Measurement of Urine Albumin: Comparison of Routine Measurement Procedures to Isotope Dilution Tandem Mass Spectrometry. Clinical Chemistry. 60:471-480. 2014
- The challenge of establishing, growing and sustaining a large biobank. Clinical Biochemistry. 47:239-244. 2014
- A Gene Variant in CERS2 Is Associated with Rate of Increase in Albuminuria in Patients with Diabetes from ONTARGET and TRANSCEND. PLoS ONE. 9:e106631-e106631. 2014
- Is the superiority of apoB over non–HDL-C as a marker of cardiovascular risk in the INTERHEART study due to confounding by related variables?. Journal of Clinical Lipidology. 7:626-631. 2013
- Prospective Urban Rural Epidemiology (PURE) study: Baseline characteristics of the household sample and comparative analyses with national data in 17 countries. American Heart Journal. 166:636-646.e4. 2013
- Effect of Insulin Glargine and n-3FA on Carotid Intima-Media Thickness in People With Dysglycemia at High Risk for Cardiovascular Events. Diabetes Care. 36:2466-2474. 2013
- Genetic Information and the Prediction of Incident Type 2 Diabetes in a High-Risk Multiethnic Population. Diabetes Care. 36:2836-2842. 2013
- Implications of adjustment of high-sensitivity cardiac troponin T assay. Clinical Chemistry. 59:574-576. 2013
- Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk. Atherosclerosis. 226:245-251. 2013
- Maternal and Pregnancy Related Predictors of Cardiometabolic Traits in Newborns. PLoS ONE. 8:e55815-e55815. 2013
- Predicting myocardial infarction and other serious cardiac outcomes using high-sensitivity cardiac troponin T in a high-risk stable population. Clinical Biochemistry. 46:5-9. 2013
- Discordance analysis of Apolipoprotein B and non-high density lipoprotein cholesterol as markers of cardiovascular risk in the INTERHEART study. Atherosclerosis. 225:444-449. 2012
- Basal Insulin and Cardiovascular and Other Outcomes in Dysglycemia. New England Journal of Medicine. 367:319-328. 2012
- n–3 Fatty Acids and Cardiovascular Outcomes in Patients with Dysglycemia. New England Journal of Medicine. 367:309-318. 2012
- Error in Viewpoint in: Statin Therapy for Healthy Men Identified as ‘Increased Risk,’. Journal of the American Medical Association (JAMA). 307:2590-2590. 2012
- Association Between Postoperative Troponin Levels and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery. Journal of the American Medical Association (JAMA). 307:2295-2295. 2012
- [The actual issues of measurement and presentation of results of albumin excretion with urine].. Laboratornoe delo. 43-53. 2012
- Urinary Sodium and Potassium Excretion and Risk of Cardiovascular Events. Journal of the American Medical Association (JAMA). 306:2229-2238. 2011
- Cardiac troponin testing in the acute care setting: Ordering, reporting, and high sensitivity assays—An update from the Canadian society of clinical chemists (CSCC). Clinical Biochemistry. 44:1273-1277. 2011
- The Effect of Chromosome 9p21 Variants on Cardiovascular Disease May Be Modified by Dietary Intake: Evidence from a Case/Control and a Prospective Study. PLoS Medicine. 8:e1001106-e1001106. 2011
- High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study. Clinical Biochemistry. 44:1021-1024. 2011
- High-Sensitivity Cardiac Troponin I Measurement for Risk Stratification in a Stable High-Risk Population. Clinical Chemistry. 57:1146-1153. 2011
- Changes in Albuminuria Predict Mortality and Morbidity in Patients with Vascular Disease. Journal of the American Society of Nephrology. 22:1353-1364. 2011
- A Meta-Analysis of Low-Density Lipoprotein Cholesterol, Non-High-Density Lipoprotein Cholesterol, and Apolipoprotein B as Markers of Cardiovascular Risk. Circulation. Cardiovascular Quality and Outcomes. 4:337-345. 2011
- Measurement of Hemoglobin A1c from Filter Papers for Population-Based Studies. Clinical Chemistry. 57:577-585. 2011
- Prognostic Value of Troponin and Creatine Kinase Muscle and Brain Isoenzyme Measurement after Noncardiac Surgery. Anesthesiology. 114:796-806. 2011
- Cardiovascular and Renal Outcomes With Telmisartan, Ramipril, or Both in People at High Renal Risk. Circulation. 123:1098-1107. 2011
- Estimated Glomerular Filtration Rate and Albuminuria as Predictors of Outcomes in Patients With High Cardiovascular Risk. ACP journal club. 154:310-310. 2011
- Dysglycaemia and the risk of acute myocardial infarction in multiple ethnic groups: an analysis of 15,780 patients from the INTERHEART study. Diabetologia. 53:2509-2517. 2010
- High sensitivity cardiac troponin testing. CANADIAN MEDICAL ASSOCIATION JOURNAL. 182:1761-1761. 2010
- Sensitive and high sensitivity cardiac troponin I concentrations in the Heart Outcomes Prevention Evaluation (HOPE) study — A high risk population. Clinica Chimica Acta. 411:1832-1832. 2010
- Current issues in measurement and reporting of urinary albumin excretion. Biochimica Clinica. 34:337-350. 2010
- High sensitivity cardiac troponin concentration cutoffs—is a healthy population the right reference population for those with underlying cardiac disease?. Clinical Biochemistry. 43:1037-1038. 2010
- Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. The Lancet. 376:112-123. 2010
- Metabolic Syndrome and Risk of Acute Myocardial Infarction. Journal of the American College of Cardiology. 55:2390-2398. 2010
- Why is non−high-density lipoprotein cholesterol a better marker of the risk of vascular disease than low-density lipoprotein cholesterol?. Journal of Clinical Lipidology. 4:152-155. 2010
- When is equal not equal?. Journal of Clinical Lipidology. 4:83-88. 2010
- Either cholesterol or apolipoprotein levels can be used to determine risk for CVD; triglycerides are not useful. ACP journal club. 152:JC2-JC2. 2010
- Current data on urinary excretion albumine dosage. Annales de Biologie Clinique. 68:9-25. 2010
- Données actuelles sur le dosage de l'excrétion urinaire de l'albumine. Annales de Biologie Clinique. 68:9-25. 2010
- Questões atuais relativas à dosagem e à descrição da excreção urinária de albumina. Jornal Brasileiro de Patologia e Medicina Laboratorial. 46:187-206. 2010
- Is a Pre-Operative Brain Natriuretic Peptide or N-Terminal Pro–B-Type Natriuretic Peptide Measurement an Independent Predictor of Adverse Cardiovascular Outcomes Within 30 Days of Noncardiac Surgery?. Journal of the American College of Cardiology. 54:1599-1606. 2009
- The Family Atherosclerosis Monitoring In earLY life (FAMILY) study. American Heart Journal. 158:533-539. 2009
- Feasibility of Biological Specimen Collection for the Canadian Longitudinal Study on Aging (CLSA) Biorepository. Canadian Journal on Aging. 28:261-274. 2009
- Effect of Telmisartan on Renal Outcomes. ACP journal club. 151:1-1. 2009
- Intra-individual variability in troponin T concentration in dialysis patients. Clinical Biochemistry. 42:991-995. 2009
- The Prospective Urban Rural Epidemiology (PURE) study: Examining the impact of societal influences on chronic noncommunicable diseases in low-, middle-, and high-income countries. American Heart Journal. 158:1-7.e1. 2009
- Novel Management of Isotretinoin-Induced Hypertriglyceridemia in an Adolescent With Severe Acne. Clinical Pediatrics. 48:551-554. 2009
- Homocysteine-Lowering Therapy and Stroke Risk, Severity, and Disability. Stroke. 40:1365-1372. 2009
- Genetic Variants Associated With Myocardial Infarction Risk Factors in Over 8000 Individuals From Five Ethnic Groups. Circulation. Genomic and precision medicine. 2:16-25. 2009
- Current Issues in Measurement and Reporting of Urinary Albumin Excretion. Clinical Chemistry. 55:24-38. 2009
- Lipid Profile, Plasma Apolipoproteins, and Risk of a First Myocardial Infarction Among Asians. Journal of the American College of Cardiology. 53:244-253. 2009
- Correlations between plasma homocysteine and folate concentrations and carotid atherosclerosis in high-risk individuals: baseline data from the Homocysteine and Atherosclerosis Reduction Trial (HART). Vascular Medicine. 13:245-253. 2008
- Requesting and Interpreting Urine Albumin Measurements in the Primary Health Care Setting. Clinical Chemistry. 54:1595-1597. 2008
- Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial. The Lancet. 372:547-553. 2008
- Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study. The Lancet. 372:224-233. 2008
- Hypogonadism is Common in Men With Myopathies. Journal of Clinical Neuromuscular Disease. 9:397-401. 2008
- A systematic review of BNP as a predictor of prognosis in persons with coronary artery disease. Clinical Biochemistry. 41:260-265. 2008
- Diagnostic accuracy of BNP and NT-proBNP in patients presenting to acute care settings with dyspnea: A systematic review. Clinical Biochemistry. 41:250-259. 2008
- Evidence for the use of B-type natriuretic peptides for screening asymptomatic populations and for diagnosis in primary care. Clinical Biochemistry. 41:240-249. 2008
- Monitoring the response to pharmacologic therapy in patients with stable chronic heart failure: Is BNP or NT-proBNP a useful assessment tool?. Clinical Biochemistry. 41:266-276. 2008
- Physiological, pathological, pharmacological, biochemical and hematological factors affecting BNP and NT-proBNP. Clinical Biochemistry. 41:231-239. 2008
- Homocysteine lowering with folic acid and B vitamins in people with chronic kidney disease--results of the renal Hope-2 study. Nephrology Dialysis Transplantation. 23:645-653. 2008
- Evidence for the use of urinary albumin as marker of kidney involvement in unselected populations. Scandinavian Journal of Clinical and Laboratory Investigation. 68:52-56. 2008
- Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention). American Heart Journal. 155:26.e1-26.e13. 2008
- Venous thromboembolism in association with features of the metabolic syndrome. QJM - Monthly Journal of the Association of Physicians. 100:679-684. 2007
- Defining Obesity Cut Points in a Multiethnic Population. Circulation. 115:2111-2118. 2007
- IFCC Position Paper: Report of the IFCC Taskforce on Ethics: Introduction and framework. Clinical Chemistry and Laboratory Medicine. 45:1098-1104. 2007
- Reevaluation by High-Performance Liquid Chromatography: Clinical Significance of Microalbuminuria in Individuals at High Risk of Cardiovascular Disease in the Heart Outcomes Prevention Evaluation (HOPE) Study. American Journal of Kidney Diseases. 48:889-896. 2006
- Effect of Ramipril on the Incidence of Diabetes. New England Journal of Medicine. 355:1551-1562. 2006
- Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. The Lancet. 368:1096-1105. 2006
- Testing for BNP and NT-proBNP in the diagnosis and prognosis of heart failure.. Evidence report/technology assessment. 1-147. 2006
- Comparative Impact of Multiple Biomarkers and N-Terminal Pro-Brain Natriuretic Peptide in the Context of Conventional Risk Factors for the Prediction of Recurrent Cardiovascular Events in the Heart Outcomes Prevention Evaluation (HOPE) Study. Circulation. 114:201-208. 2006
- Long term fenofibrate did not reduce major coronary events but may reduce total CVD events in type 2 diabetes. BMJ Evidence-Based Medicine. 11:86-86. 2006
- Detection of ischemic myocardial injury in patients with normal, or moderately elevated, serum CK and AST actitivities (reprinted from Clinical Biochemistry, 1982, vol. 15, pg. 138-140). Clinical Biochemistry. 39:468-470. 2006
- Folic acid improves endothelial dysfunction in type 2 diabetes - an effect independent of homocysteine-lowering. Vascular Medicine. 11:101-109. 2006
- Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease. New England Journal of Medicine. 354:1567-1577. 2006
- Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: The Heart Outcomes Prevention Evaluation (HOPE)-2 trial. Canadian Journal of Cardiology. 22:47-53. 2006
- The relationship between dysglycaemia and cardiovascular and renal risk in diabetic and non-diabetic participants in the HOPE study: a prospective epidemiological analysis. Diabetologia. 48:1749-1755. 2005
- The HOPE (Heart Outcomes Prevention Evaluation) Study and its Consequences. Scandinavian Journal of Clinical and Laboratory Investigation. 65:143-156. 2005
- The Effect of Vitamin E Supplementation on Cardiovascular Risk in Diabetic Individuals With Different Haptoglobin Phenotypes. Diabetes Care. 27:2767-2767. 2004
- Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. The Lancet. 364:937-952. 2004
- Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: the DREAM trial. Diabetologia. 47:1519-1527. 2004
- C-Reactive Protein as a Screening Test for Cardiovascular Risk in a Multiethnic Population. Arteriosclerosis, Thrombosis and Vascular Biology. 24:1509-1515. 2004
- Can troponin I measurement predict short-term serious cardiac outcomes in patients presenting to the emergency department with possible acute coronary syndrome?. Canadian Journal of Emergency Medicine. 6:22-30. 2004
- Effect of cyclooxygenase-2 inhibition with rofecoxib on endothelial dysfunction and inflammatory markers in patients with coronary artery disease. Journal of the American College of Cardiology. 42:1747-1753. 2003
- Towards Complete and Accurate Reporting of Studies of Diagnostic Accuracy: The STARD Initiative. Clinical Radiology. 58:575-580. 2003
- The STARD initiative: a possible link to diagnostic accuracy and reduction in medical error. Annals of Clinical Biochemistry. 40:307-308. 2003
- Evidence-Based Laboratory Medicine: Addressing Bias, Generalisability and Applicability in Studies on Diagnostic Accuracy. The STARD Initiative. Clinical Chemistry and Laboratory Medicine. 41:1-1. 2003
- Evaluation of Cobas Integra® 800 under Simulated Routine Conditions in Six Laboratories. Clinical Chemistry and Laboratory Medicine. 41:365-381. 2003
- Multiple Infections and Subsequent Cardiovascular Events in the Heart Outcomes Prevention Evaluation (HOPE) Study. Circulation. 107:251-257. 2003
- The Relationship Between Dysglycemia and Atherosclerosis in South Asian, Chinese, and European Individuals in Canada. Diabetes Care. 26:144-149. 2003
- Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Clinical Biochemistry. 36:1-7. 2003
- Relationship of Anti-60 kDa Heat Shock Protein and Anti-Cholesterol Antibodies to Cardiovascular Events. Circulation. 106:2775-2780. 2002
- A comparison of pravastatin and gemfibrozil in the treatment of dyslipoproteinemia in patients with non-insulin-dependent diabetes mellitus. Atherosclerosis. 162:201-210. 2002
- Screening for the early detection of disease, the need for evidence. Clinica Chimica Acta. 315:5-15. 2002
- Some ethical and design challenges of screening programs and screening tests. Clinica Chimica Acta. 315:41-48. 2002
- Overview of Evidence-based Medicine: Challenges for Evidence-based Laboratory Medicine. Clinical Chemistry. 47:1536-1546. 2001
- The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme. Rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease. European Heart Journal. 21:2033-2041. 2000
- Differences in risk factors, atherosclerosis, and cardiovascular disease between ethnic groups in Canada: the Study of Health Assessment and Risk in Ethnic groups (SHARE). The Lancet. 356:279-284. 2000
- The surface effect of dentifrices. Australian Dental Journal. 45:118-124. 2000
- Use of Statins and Fibrates in Hyperlipidemic Patients with Neuromuscular Disorders. ACP journal club. 132:418-418. 2000
- Evidence-Based Medicine: Its Application to Laboratory Medicine. Therapeutic Drug Monitoring. 22:1-9. 2000
- Creating and Managing an Integrated Department of Laboratory Medicine in an Academic Centre. SLAS Technology. 4:68-70. 1999
- Monthly intra-individual variation in lipids over a 1-year period in 22 normal subjects. Clinical Biochemistry. 32:381-389. 1999
- Evolution or Revolution in Clinical Chemistry. Clinical Chemistry and Laboratory Medicine. 37:89-90. 1999
- [Laboratory medicine: the future of the profession].. Laboratornoe delo. 43-46. 1999
- Biological Variation in Lipoprotein(a). Clinical Chemistry and Laboratory Medicine. 37:85-86. 1999
- The study of health assessment and risk in ethnic groups (SHARE): Rationale and design. Canadian Journal of Cardiology. 14:1349-1357. 1998
- Cholesteryl Ester Transfer Protein Mutations, Protein Activity and HDL-Cholesterol Concentration. Clinical Chemistry and Laboratory Medicine. 36:629-632. 1998
- Ethical and Legal Issues in the Procurement, Storage and Use of DNA. Clinical Chemistry and Laboratory Medicine. 36:545-549. 1998
- Blood lipid profiles in children with acute lymphoblastic leukemia. Cancer. 83:379-384. 1998
- << Point-of-care >> or << point-of-need >>?. Annales de Biologie Clinique. 56:487-490. 1998
- ["Point-of-care" or "point-of-need"? Tentative definition of common technology].. Annales de Biologie Clinique. 56:487-490. 1998
- Laboratory quality assurance at the international level: the role of nongovernmental organizations.. Journal of the International Federation of Clinical Chemistry. 9:144-150. 1997
- Reverse Cholesterol Transport—A Review of the Process and Its Clinical Implications. Clinical Biochemistry. 30:517-525. 1997
- Realistic dietary changes in type, but not amount of, dietary fat reduced LDL and total blood cholesterol. Evidence-based Cardiovascular Medicine. 1:70-70. 1997
- Mutations in cholesteryl ester transfer protein and hepatic lipase in a North American population. Clinical Biochemistry. 30:413-418. 1997
- Monthly intra-individual variation in lipoprotein(a) in 22 normal subjects over 12 months. Clinical Biochemistry. 30:163-170. 1997
- A double‐blind randomised controlled trial of the effects of medroxyprogesterone acetate on bone density of women taking oestrogen replacement therapy. BJOG: An International Journal of Obstetrics and Gynaecology. 104:64-70. 1997
- Will physicians and scientists have any role in managing laboratory resources in the year 2000?. Clinical Chemistry and Laboratory Medicine. 34:867-871. 1996
- Clinical Chemistry—Twilight or Dawn?. Annals of Clinical Biochemistry. 33:271-272. 1996
- Reference materials and reference measurement systems in laboratory medicine--a major international meeting organized by the International Federation of Clinical Chemistry (IFCC), Geneva, October 5-7, 1994.. Clinical Chemistry and Laboratory Medicine. 33:977-979. 1995
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- Evaluation of a turbidimetric procedure for apolipoproteins A1 and B on the Ciba Corning 550 EXPRESS. Clinical Biochemistry. 26:477-482. 1993
- The ethics and economics of out-of-laboratory testing.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 149:1653-1656. 1993
- Hamilton Health Sciences Laboratory Program: A Provider Developed Model for Hospital, University and Community Laboratory Services. Healthcare Management Forum. 6:35-42. 1993
- Lovastatin 5-year safety and efficacy study. Lovastatin Study Groups I through IV. JAMA Internal Medicine. 153:1079-1087. 1993
- An overview of the conference. Clinical Biochemistry. 26:1-3. 1993
- Role of the laboratory in meeting the needs of critical care. Clinical Biochemistry. 26:8-10. 1993
- New Whole Blood Analyzers and Their Impact on Cardiac and Critical Care. Critical Reviews in Clinical Laboratory Sciences. 30:153-202. 1993
- The application of universal precautions.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 147:1115-1116. 1992
- Conflicting rights of patients and health care workers exposed to blood-borne infection.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 147:299-302. 1992
- Testing for Creatine Kinase and Creatine Kinase-2 in Ontario: Reference Ranges and Assay Types. Clinical Chemistry. 38:1365-1370. 1992
- Comparison of the short-term efficacy and tolerability of lovastatin and pravastatin in the management of primary hypercholesterolemia.. Clinical Therapeutics. 14:276-291. 1992
- Results of a province-wide quality assurance program assessing the accuracy of cholesterol, triglycerides, and high-density lipoprotein cholesterol measurements and calculated low-density lipoprotein cholesterol in Ontario, using fresh human serum.. Archives of Pathology and Laboratory Medicine. 115:1217-1222. 1991
- Proficiency testing for creatine kinase isoenzyme CK-2 (CK-MB) in Ontario. Clinical Chemistry. 36:2102-2105. 1990
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- CHOLESTATIC JAUNDICE ASSOCIATED WITH LOVASTATIN (MEVACOR) THERAPY - RESPONSE. CANADIAN MEDICAL ASSOCIATION JOURNAL. 143:14-14. 1990
- Cholestatic jaundice associated with lovastatin (Mevacor) therapy.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 142:841-842. 1990
- The significance of matrix effects on the measurement of lactate dehydrogenase (LD) activity using kodak dry slide technology in the ontario laboratory proficiency testing program. Clinical Biochemistry. 23:179-181. 1990
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- Mercury exposure: an evaluation.. Dimensions in health service. 60:22-24. 1983
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- Why measure total lactate dehydrogenase activity?. Clinical Chemistry. 25:1869-1869. 1979
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- Inhibition inversion in the AACC selected method for serum cholinesterase.. Clinical Chemistry. 25:1511-1512. 1979
- Abnormal enzyme phenotype (e1 a e1 f): Normal response to succinylcholine. Canadian Journal of Anaesthesia. 26:99-103. 1979
- Lipoidal Bladder Concretion: An Unusual Autopsy Finding in Acute Lymphoblastic Leukemia. Investigative Urology. 121:248-250. 1979
- Evaluation of an automated immunoassay procedure for APO-LDL for phenotyping type II hyperlipoproteinemia. Clinica Chimica Acta. 88:31-36. 1978
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- Use of a programmable calculator in processing and interpreting serum cholinesterase phenotypes.. Clinical Chemistry. 24:223-226. 1978
- Succinylcholine sensitivity in a nova scotia family. Canadian Journal of Anaesthesia. 25:53-59. 1978
- Evaluation of the Vitatron Automatic Kinetic Enzyme System. Clinica Chimica Acta. 64:155-164. 1975
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- Diagnosis of Heart and Liver Disease. Clinical Chemistry. 21:177-177. 1975
- True Arrhenius Relationships of Human Lactate Dehydrogenase. Clinical Chemistry and Laboratory Medicine. 13:17-19. 1975
- Evaluation of the Vitatron automatic kinetic enzyme system.. Clinical Chemistry and Laboratory Medicine. 12:235. 1974
- True Arrhenius relationship of human lactate dehydrogenase.. Clinical Chemistry and Laboratory Medicine. 12:227. 1974
- Inhibition and Activation of Human Lactate Dehydrogenase by Urea. Annals of Clinical Biochemistry. 11:75-80. 1974
- Normal values at 37° for serum lactate dehydrogenase, α-hydroxybutyrate dehydrogenase and glycerate dehydrogenase. Clinica Chimica Acta. 46:5-10. 1973
- Effects of temperature and substrate concentration on the LDH/α-HBD ratio in heart and liver disease. Clinica Chimica Acta. 43:397-403. 1973
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- "Glycerate Dehydrogenase" Activity in Acute Myocardial Infarction and Myocardial Ischemia. Clinical Chemistry. 18:275-279. 1972
- Transient systolic hypertension after aortic valve replacement.. Heart. 34:227-231. 1972
- An Initial Reaction Rate Assay for "Glycerate Dehydrogenase". Clinical Chemistry. 17:1089-1092. 1971
- Normal range for serum transaminase.. The BMJ. 4:299-299. 1971
- THE EFFECT OF TEMPERATURE ON FLUORIDE-RESISTANT SERUM CHOLINESTERASE. British Journal of Anaesthesia. 43:669-672. 1971
- The Reduction of Hydroxypyruvate by Human Serum. Enzyme and Protein. 12:523-528. 1971
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Determinants of serious health