Journal article
Validation of a Capillary Electrophoresis Assay for Monitoring Iodine Nutrition in Populations for Prevention of Iodine Deficiency: An Interlaboratory Method Comparison
Abstract
BACKGROUND: A capillary electrophoresis (CE) assay was recently introduced as a new method for monitoring iodine nutrition in large-scale epidemiological studies. However, further tests revealed unanticipated matrix-dependent interferences when analyzing submicromolar levels of iodide in human urine as the predominate ionic form of dietary iodine. Herein, we describe a rigorous validation study that was used to identify sources of bias and …
Authors
de Macedo AN; Macri J; Hudecki PL; Saoi M; McQueen MJ; Britz-McKibbin P
Journal
The Journal of Applied Laboratory Medicine, Vol. 1, No. 6, pp. 649–660
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 2017
DOI
10.1373/jalm.2016.022848
ISSN
2576-9456