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Abnormal enzyme phenotype (e1a e1f): Normal...
Journal article

Abnormal enzyme phenotype (e1a e1f): Normal response to succinylcholine

Abstract

The enzyme serum cholinesterase responsible for the hydrolysis of the muscle relaxant succinylcholine exists in the form of several variants. These may be identified in serum by using substances which inhibit their activity to different degrees. The heterozygote for the atypical and fluoride resistant enzymes (E1a E1f) is one of the phenotypes which has been reported to be sensitive to succinylcholine.A case is described where succinylcholine …

Authors

McQueen MJ; Lepinskie F; Strickland RD; Trimble A

Journal

Journal canadien d'anesthésie, Vol. 26, No. 2,

Publisher

Springer Nature

Publication Date

March 1979

DOI

10.1007/bf03013777

ISSN

0832-610X