Homocysteine-Lowering Therapy and Stroke Risk, Severity, and Disability

BACKGROUND AND PURPOSE: Elevated total homocysteine is associated with a higher risk of cerebrovascular disease. It is not known whether lowering homocysteine impacts on stroke risk, both in terms of severity and ischemic vs hemorrhagic stroke subtypes. Our aim was to determine whether vitamin therapy reduces the risk of ischemic and hemorrhagic stroke, as well as stroke-related disability. METHODS: We analyzed stroke outcomes among …