High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study Academic Article uri icon

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abstract

  • OBJECTIVES: To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay. DESIGN AND METHODS: We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults. RESULTS: Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT≥14ng/L and 22% (95% CI:17-26%) had an elevation (≥14ng/L) and change (>85%) in hs-TnT. CONCLUSION: Further research is needed to inform the optimal hs-TnT threshold and change in this setting.

authors

  • Kavsak, Peter
  • Walsh, Mike
  • Srinathan, Sadeesh
  • Thorlacius, Laurel
  • Buse, Giovanna Lurati
  • Botto, Fernando
  • Pettit, Shirley
  • Mcqueen, Matthew
  • Hill, Stephen
  • Thomas, Sabu
  • Mrkobrada, Marko
  • Alonso, Pablo
  • Berwanger, Otavio
  • Biccard, Bruce M
  • Cembrowski, George
  • Chan, Matthew TV
  • Chow, Clara K
  • de Miguel, Angeles
  • Garcia, Mercedes
  • Graham, Michelle M
  • Jacka, Michael J
  • Kueh, JH
  • Li, Stephen CH
  • Lit, Lydia CW
  • Martínez-Brú, Cecília
  • Naidoo, Prebashini
  • Nagele, Peter
  • Pearse, Rupert M
  • Rodseth, Reitze N
  • Sessler, Daniel I
  • Sigamani, Alben
  • Szczeklik, Wojciech
  • Tiboni, Maria
  • Villar, Juan Carlos
  • Wang, CY
  • Xavier, Denis
  • Devereaux, Philip

publication date

  • August 2011