Age of Onset
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50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis Academic Article
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A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function Academic Article
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A Longitudinal, Population-Based, Cohort Study of Childhood Asthma Followed to Adulthood Academic Article
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A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors Academic Article
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A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors Academic Article
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A heteroplasmic mitochondrial complex I gene mutation in adult-onset dystonia Academic Article
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A large-scale candidate gene association study of age at menarche and age at natural menopause Academic Article
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A mitochondrial disorder with ptosis and exercise intolerance without ophthalmoparesis secondary to m.5865 T > C variant Academic Article
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A new highly penetrant form of obesity due to deletions on chromosome 16p11.2 Academic Article
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A novel homozygous GALC mutation: Very early onset and rapidly progressive Krabbe disease Academic Article
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A systematic review of integrative clinical trials for supportive care in pediatric oncology: a report from the International Society of Pediatric Oncology, T&CM collaborative Academic Article
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Access to essential medicines for children with cancer: a joint SIOP-CCI position statement Academic Article
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Acute myelogenous leukemia in adolescents and young adults Academic Article
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Adjuvant Treatment and Onset of Menopause Predict Weight Gain After Breast Cancer Diagnosis Academic Article
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Adolescent Nonalcoholic Fatty Liver Disease and Type 2 Diabetes in Young Adulthood Academic Article
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Adolescent Obesity and Early-Onset Type 2 Diabetes Academic Article
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Adults with Mood Disorders Have an Increased Risk Profile for Cardiovascular Disease within the First 2 Years of Treatment Academic Article
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Advances in the molecular classification of pediatric brain tumors: a guide to the galaxy Academic Article
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Age of First Faint in Patients with Vasovagal Syncope Academic Article
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Age of onset of recurrent respiratory papillomatosis: a distribution analysis Academic Article
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Age-of-Onset Classification of Conduct Disorder: Reliability and Validity in a Prospective Cohort Study Academic Article
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Age-related variables in childhood epilepsy: How do they relate to each other and to quality of life? Academic Article
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Alternate forms of logical memory and verbal fluency tasks for repeated testing in early cognitive changes Academic Article
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Alzheimer’s and other dementias in Canada, 2011 to 2031: a microsimulation Population Health Modeling (POHEM) study of projected prevalence, health burden, health services, and caregiving use Academic Article
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An Open Trial of Topiramate in the Treatment of Generalized Social Phobia Academic Article
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Analysis of Environmental Factors in Familial Versus Sporadic Paget's Disease of Bone-The New England Registry for Paget's Disease of Bone Academic Article
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Anterior Cingulate Volumes in Never-Treated Patients with Major Depressive Disorder Academic Article
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Are there differences between young- and older-onset early inflammatory arthritis and do these impact outcomes? An analysis from the CATCH cohort Academic Article
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Association between age at disease onset of anti-neutrophil cytoplasmic antibody–associated vasculitis and clinical presentation and short-term outcomes Academic Article
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Association between solar insolation and a history of suicide attempts in bipolar I disorder Academic Article
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Association of interleukin-10 levels with age of onset and duration of illness in patients with major depressive disorder Academic Article
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Associations Between Methotrexate Use and the Risk of Cardiovascular Events in Patients with Elderly-onset Rheumatoid Arthritis Academic Article
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Bipolar disorder and tobacco smoking: Categorical and dimensional clinical correlates in subjects from the Brazilian bipolar research network Academic Article
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Birth-cohort and dual diagnosis effects on age-at-onset in Brazilian patients with bipolar I disorder Academic Article
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Brain type carnosinase in dementia: a pilot study Academic Article
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Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder Academic Article
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Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample Academic Article
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Cardiovascular Disease in South Asian Migrants Academic Article
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Changes in cortical thickness across the lifespan in major depressive disorder Academic Article
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Childhood Pancreatitis and Risk for Incident Diabetes in Adulthood Academic Article
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Childhood maltreatment and DSM-IV adult mental disorders: Comparison of prospective and retrospective findings Academic Article
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Childhood, adolescent and adult age at onset and related clinical correlates in obsessive–compulsive disorder: a report from the International College of Obsessive–Compulsive Spectrum Disorders (ICOCS) Academic Article
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Chronic Immune Thrombocytopenic Purpura in Children Academic Article
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Classification schemes for tumors diagnosed in adolescents and young adults Academic Article
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Clinical delineation of myasthenia gravis in the Kingdom of Bahrain Academic Article
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Clinical impact of late diagnose of bipolar disorder Academic Article
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Clinical implications of a staging model for bipolar disorders Academic Article
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Clinical spectrum of the pseudotumor cerebri in children: Etiological, clinical features, treatment and prognosis Academic Article
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Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood Academic Article
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Colorectal cancer in adolescents and young adults: Defining a growing threat Academic Article
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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease Academic Article
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Comparative Effectiveness of Mycophenolate Mofetil for the Treatment of Juvenile‐Onset Proliferative Lupus Nephritis Academic Article
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Complex two-gene modulation of lung disease severity in children with cystic fibrosis Academic Article
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Coronary artery disease surveillance among childhood, adolescent and young adult cancer survivors: A systematic review and recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group Academic Article
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Correlates and impact of obsessive-compulsive comorbidity in bipolar disorder Academic Article
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Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group Academic Article
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Creatine supplementation and riluzole treatment provide similar beneficial effects in copper, zinc superoxide dismutase (G93A) transgenic mice Academic Article
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De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy Academic Article
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Determinants of delays in treatment initiation in children and adolescents diagnosed with leukemia or lymphoma in Canada Academic Article
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Development and Validation of SDBeasy Score as a Predictor of Behavioral Outcomes in Childhood Academic Article
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Diagnosis of Huntington disease: A model for the stages of psychological response based on experience of a predictive testing program Academic Article
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Differences between unipolar mania and bipolar‐I disorder: Evidence from nine epidemiological studies Academic Article
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Differences in health, participation and life satisfaction outcomes in adults following paediatric- versus adult-sustained spinal cord injury Academic Article
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Disability and Health-related Quality of Life in Long-term Survivors of Cancer in Childhood in Brazil Academic Article
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Disease Variant Landscape of a Large Multiethnic Population of Moyamoya Patients by Exome Sequencing Academic Article
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Does family history predict the age at onset of new breast cancers inBRCA1andBRCA2mutation-positive families? Academic Article
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Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation Academic Article
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Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer Academic Article
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EARLY-LIFE PREDICTORS OF INTERNALIZING SYMPTOM TRAJECTORIES IN CANADIAN CHILDREN Academic Article
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Early-Onset Developmental and Epileptic Encephalopathies of Infancy: An Overview of the Genetic Basis and Clinical Features Academic Article
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Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease Academic Article
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Efficacy of a Long-Acting Growth Hormone (GH) Preparation in Patients with Adult GH Deficiency Academic Article
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Epidemiology of Social Phobia in Later Life Academic Article
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Evidence of linkage in subtypes of alcoholism Academic Article
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Examining early and late onset of multimorbidity in the Canadian Longitudinal Study on Aging Academic Article
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Exercise Not Asthma Academic Article
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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction Academic Article
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Factors affecting postoperative stereopsis in acquired nonaccommodative esotropia Academic Article
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Factors contributing to the duration of untreated psychosis Academic Article
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Female and male antisocial trajectories: From childhood origins to adult outcomes Academic Article
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Field trial for autistic disorder in DSM-IV Academic Article
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Genetics of early-onset coronary artery disease Academic Article
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Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants Academic Article
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Genotypes of chronic progressive external ophthalmoplegia in a large adult-onset cohort Academic Article
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HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome Academic Article
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Health-related Quality of Life in Long-term Survivors of Brain Tumors in Childhood and Adolescence Academic Article
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Hepatic Lipase Deficiency Delays Atherosclerosis, Myocardial Infarction, and Cardiac Dysfunction and Extends Lifespan in SR-BI/Apolipoprotein E Double Knockout Mice Academic Article
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Hepatoblastoma in a Child With Early-onset Cirrhosis Academic Article
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Hereditary risk factors for the development of gastric cancer in younger patients Academic Article
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Heterogeneity in presentation and treatment of catamenial anaphylaxis Academic Article
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Hyperhomocysteinemia as a cause of premature stroke in a young patient Academic Article
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IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies Academic Article
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IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies. Academic Article
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IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis Academic Article
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Illness burden and medical comorbidity in the Systematic Treatment Enhancement Program for Bipolar Disorder Academic Article
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Imaging Predictors of Neurologic Outcome After Pediatric Arterial Ischemic Stroke Academic Article
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Impact of Comorbid Anxiety Disorders on Outcome in a Cohort of Patients With Bipolar Disorder Academic Article
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Impact of sunlight on the age of onset of bipolar disorder Academic Article
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Implicit and explicit alcohol-related motivations among college binge drinkers Academic Article
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Incidence and Remission of Nocturia: A Systematic Review and Meta-analysis Academic Article
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Incidence of new-onset diabetes mellitus and association with mortality in childhood solid organ transplant recipients: a population-based study Academic Article
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Infantile-Onset Syndromic Cerebellar Ataxia and CACNA1G Mutations Academic Article
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Influence of birth cohort on age of onset cluster analysis in bipolar I disorder Academic Article
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Influence of light exposure during early life on the age of onset of bipolar disorder Academic Article
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Interaction between SLC6A4 promoter variants and childhood trauma on the age at onset of bipolar disorders Academic Article
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Interventions for cutaneous disease in systemic lupus erythematosus Academic Article
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Italian Registry of Haemophilia and Allied Disorders. Objectives, methodology and data analysis Academic Article
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Juvenile onset of Crohn's disease: A risk factor for reduced lumbar bone mass in premenopausal women Academic Article
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Late onset mania in the elderly Academic Article
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Late-Onset Adrenoleukodystrophy Associated With Long-Standing Psychiatric Symptoms Academic Article
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Late-onset Tay-Sachs disease presenting as catatonic schizophrenia: diagnostic and treatment issues. Academic Article
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Lifetime Prevalence of Mental Disorders in U.S. Adolescents: Results from the National Comorbidity Survey Replication–Adolescent Supplement (NCS-A) Academic Article
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Long-Term Follow-up of Asthma Academic Article
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Long-term seizure and social outcomes following temporal lobe surgery for intractable epilepsy during childhood Academic Article
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Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and Premature Death in Apolipoprotein E–Deficient Mice Academic Article
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Mammographic features of pure mucinous carcinoma of the breast with pathological correlation. Academic Article
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Manifestaciones iniciales de los trastornos del espectro autista. Experiencia en 393 casos atendidos en un centro neurológico infantil Academic Article
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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease Academic Article
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Moderators of Naltrexone’s Effects on Drinking, Urge, and Alcohol Effects in Non-Treatment-Seeking Heavy Drinkers in the Natural Environment Academic Article
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Mood disorder service genetic database: Morbidity risks for mood disorders in 3,942 first-degree relatives of 671 index cases with single depression, recurrent depression, bipolar I, or bipolar II Academic Article
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Mortality rates and causes of death among all HIV-positive individuals with hemophilia in Canada over 21 years of follow-up Academic Article
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Mutations inKCNT1cause a spectrum of focal epilepsies Academic Article
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Myasthenia gravis: A study from India Academic Article
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Myopia and Early-Onset Type 2 Diabetes: A Nationwide Cohort Study Academic Article
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No Association between the 20210 G/A Prothrombin Gene Mutation and Premature Coronary Artery Disease Academic Article
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Novel GAA sequence variant c.1211 A>G reduces enzyme activity but not protein expression in infantile and adult onset Pompe disease Academic Article
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Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure Academic Article
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Obsessive-compulsive disorder (OCD): is this disorder under-recognized? Academic Article
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Obsessive-compulsive disorder in the elderly: A report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) Academic Article
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Ovarian Failure Related to Eukaryotic Initiation Factor 2B Mutations Academic Article
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Overweight and incident hypertension: does age of onset matter? Academic Article
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Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: The Canadian Healthy Infant Longitudinal Development Birth Cohort Study Academic Article
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Pediatric modification of the Montreal classification for inflammatory bowel disease Academic Article
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Pediatric superior vena cava syndrome: An evidence‐based systematic review of the literature Academic Article
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Perinatal Exposures and Breast Cancer Risk in the Western New York Exposures and Breast Cancer (WEB) Study Academic Article
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Phenotypes of sleep-disordered breathing symptoms to two years of age based on age of onset and duration of symptoms Academic Article
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Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. Academic Article
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Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C→T (Arg493X) mutation: an international initiative Academic Article
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Physical Activity in Long-term Survivors of Acute Lymphoblastic Leukemia in Childhood and Adolescence: A Cross-sectional Cohort Study Academic Article
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Polypharmacy and suicide attempts in bipolar disorder Academic Article
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Prediction of Differential Adult Health Burden by Conduct Problem Subtypes in Males Academic Article
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Predictors of Response in Generalized Social Phobia Academic Article
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Predominant polarity in bipolar disorder: Diagnostic implications Academic Article
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Presentation and Disease Course of Childhood‐Onset Versus Adult‐Onset Takayasu Arteritis Academic Article
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Prevalence and age of onset of Parkinson's disease in Cardiff: a community based cross sectional study and meta-analysis Academic Article
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Prevalence of Hypertension and Albuminuria in Pediatric Type 2 Diabetes Academic Article
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Prevalence of new-onset vestibular symptoms following cochlear implantation. Academic Article
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Prevalence of pyridoxine dependent seizures in south Indian children with early onset intractable epilepsy: A hospital based prospective study Academic Article
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Primary angiitis of the CNS diagnosed by angiography Academic Article
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Primary early onset dysthymia, biochemical correlates of the therapeutic response to fluoxetine: II. Urinary metabolites of serotonin, norepinephrine, epinephrine and melatonin Academic Article
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Psychiatric and clinical correlates of rapid cycling bipolar disorder: a cross-sectional study Academic Article
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Quality care in seniors with new-onset rheumatoid arthritis: A Canadian perspective Academic Article
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Recommendations for future research in relation to pediatric pulmonary embolism: communication from the SSC of the ISTH Academic Article
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Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus Academic Article
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Relationship between sunlight and the age of onset of bipolar disorder: An international multisite study Academic Article
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Relationship of Childhood Sexual and Physical Abuse to Anxiety Disorders Academic Article
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Relevance of Birth Cohorts to Assessment of Asthma Persistence Academic Article
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Reports of abnormal cervical cancer screening tests in systemic sclerosis Academic Article
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Risk Factors for Airway Remodeling in Asthma Manifested by a Low Postbronchodilator FEV1/Vital Capacity Ratio Academic Article
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Risk factors for health-related quality of life in children with epilepsy: A meta-analysis Academic Article
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Screening for Cognitive Impairment in General Practice Academic Article
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Self‐reported quality of life and degree of youth‐parent agreement: A long‐term follow‐up of childhood‐onset epilepsy Academic Article
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Serum brain-derived neurotrophic factor in patients with trauma psychopathology Academic Article
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Sex Differences in Factors Associated with Childhood- and Adolescent-Onset Wheeze Academic Article
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Similarities in serum oxidative stress markers and inflammatory cytokines in patients with overt schizophrenia at early and late stages of chronicity Academic Article
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Simplified Canadian Definition for Familial Hypercholesterolemia Academic Article
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Solar insolation in springtime influences age of onset of bipolar I disorder Academic Article
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Staging bipolar disorder: clinical, biochemical, and functional correlates Academic Article
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Substantial practice variation exists in the management of childhood nephrotic syndrome Academic Article
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The Course of Asthma in Churg–Strauss Syndrome Academic Article
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The Magnetic Resonance Imaging Appearance of Monophasic Acute Disseminated Encephalomyelitis Academic Article
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The Neuropsychiatry of Adult-Onset Adrenoleukodystrophy Academic Article
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The Position of the Polycystic Kidney Disease 1 (PKD1) Gene Mutation Correlates with the Severity of Renal Disease Academic Article
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The Relationship Between Childhood Physical Abuse and Suicidality Among Depressed Women: Results From a Community Sample Academic Article
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The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy Academic Article
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The hereditary adult-onset ataxias in South Africa Academic Article
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The influence of age at onset and duration of illness on long-term outcome in patients with obsessive-compulsive disorder: A report from the International College of Obsessive Compulsive Spectrum Disorders (ICOCS) Academic Article
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The motor phenotype of Parkinson's disease in relation to age at onset Academic Article
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The motor phenotype of Parkinson's disease in relation to age at onset. Academic Article
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The multiple facets of pulmonary sequestration Conference Paper
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The need for inclusion of sex and age of onset variables in genetic association studies of obsessive–compulsive disorder: Overview Academic Article
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Toward the Cure of All Children With Cancer Through Collaborative Efforts: Pediatric Oncology As a Global Challenge Academic Article
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Validation of the Symptom Screening in Pediatrics Tool in Children Receiving Cancer Treatments Academic Article
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Worsening of Symptoms Before Presentation with Vasovagal Syncope Academic Article