Age of Onset Concept

subject area of

• 50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis  Journal Articles
• A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function  Journal Articles
• A Longitudinal, Population-Based, Cohort Study of Childhood Asthma Followed to Adulthood  Journal Articles
• A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors  Journal Articles
• A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors  Journal Articles
• A heteroplasmic mitochondrial complex I gene mutation in adult-onset dystonia  Journal Articles
• A large-scale candidate gene association study of age at menarche and age at natural menopause  Journal Articles
• A mitochondrial disorder with ptosis and exercise intolerance without ophthalmoparesis secondary to m.5865 T > C variant  Journal Articles
• A new highly penetrant form of obesity due to deletions on chromosome 16p11.2  Journal Articles
• A novel homozygous GALC mutation: Very early onset and rapidly progressive Krabbe disease  Journal Articles
• A systematic review of integrative clinical trials for supportive care in pediatric oncology: a report from the International Society of Pediatric Oncology, T&CM collaborative  Journal Articles
• Access to essential medicines for children with cancer: a joint SIOP-CCI position statement  Journal Articles
• Acute myelogenous leukemia in adolescents and young adults  Journal Articles
• Adolescent Nonalcoholic Fatty Liver Disease and Type 2 Diabetes in Young Adulthood  Journal Articles
• Adolescent Obesity and Early-Onset Type 2 Diabetes  Journal Articles
• Adults with Mood Disorders Have an Increased Risk Profile for Cardiovascular Disease within the First 2 Years of Treatment  Journal Articles
• Advances in the molecular classification of pediatric brain tumors: a guide to the galaxy  Journal Articles
• Age-of-Onset Classification of Conduct Disorder: Reliability and Validity in a Prospective Cohort Study  Journal Articles
• Age-related variables in childhood epilepsy: How do they relate to each other and to quality of life?  Journal Articles
• Alternate forms of logical memory and verbal fluency tasks for repeated testing in early cognitive changes  Journal Articles
• Alzheimer’s and other dementias in Canada, 2011 to 2031: a microsimulation Population Health Modeling (POHEM) study of projected prevalence, health burden, health services, and caregiving use  Journal Articles
• An Open Trial of Topiramate in the Treatment of Generalized Social Phobia  Journal Articles
• Analysis of Environmental Factors in Familial Versus Sporadic Paget's Disease of Bone—The New England Registry for Paget's Disease of Bone  Journal Articles
• Anterior Cingulate Volumes in Never-Treated Patients with Major Depressive Disorder  Journal Articles
• Are there differences between young- and older-onset early inflammatory arthritis and do these impact outcomes? An analysis from the CATCH cohort  Journal Articles
• Arthrodiastasis and surgical containment in severe late-onset Perthes disease: an analysis of 14 patients.  Journal Articles
• Association between age at disease onset of anti-neutrophil cytoplasmic antibody–associated vasculitis and clinical presentation and short-term outcomes  Journal Articles
• Association between solar insolation and a history of suicide attempts in bipolar I disorder  Journal Articles
• Association of interleukin-10 levels with age of onset and duration of illness in patients with major depressive disorder  Journal Articles
• Associations Between Methotrexate Use and the Risk of Cardiovascular Events in Patients with Elderly-onset Rheumatoid Arthritis  Journal Articles
• Bipolar disorder and tobacco smoking: Categorical and dimensional clinical correlates in subjects from the Brazilian bipolar research network  Journal Articles
• Birth‐cohort and dual diagnosis effects on age‐at‐onset in Brazilian patients with bipolar I disorder  Journal Articles
• Brain type carnosinase in dementia: a pilot study  Journal Articles
• Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder  Journal Articles
• Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample  Journal Articles
• Cardiovascular Disease in South Asian Migrants  Journal Articles
• Changes in cortical thickness across the lifespan in major depressive disorder  Journal Articles
• Characteristics of Patients With Adult-Onset Dermatomyositis at 2 Tertiary Care Centres in Ontario, Canada.  Journal Articles
• Childhood Pancreatitis and Risk for Incident Diabetes in Adulthood  Journal Articles
• Childhood, adolescent and adult age at onset and related clinical correlates in obsessive–compulsive disorder: a report from the International College of Obsessive–Compulsive Spectrum Disorders (ICOCS)  Journal Articles
• Choroid Plexus Volume in Pediatric-Onset Multiple Sclerosis.  Journal Articles
• Chronic Immune Thrombocytopenic Purpura in Children  Journal Articles
• Classification schemes for tumors diagnosed in adolescents and young adults  Journal Articles
• Clinical delineation of myasthenia gravis in the Kingdom of Bahrain  Journal Articles
• Clinical impact of late diagnose of bipolar disorder  Journal Articles
• Clinical implications of a staging model for bipolar disorders  Journal Articles
• Clinical spectrum of the pseudotumor cerebri in children: Etiological, clinical features, treatment and prognosis  Journal Articles
• Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood  Journal Articles
• Cognitive function in adolescence and the risk of early-onset stroke  Journal Articles
• Colorectal cancer in adolescents and young adults: Defining a growing threat  Journal Articles
• Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease  Journal Articles
• Comparative Effectiveness of Mycophenolate Mofetil for the Treatment of Juvenile‐Onset Proliferative Lupus Nephritis  Journal Articles
• Complex two-gene modulation of lung disease severity in children with cystic fibrosis  Journal Articles
• Contralateral Breast Cancer in BRCA1 and BRCA2 Mutation Carriers  Journal Articles
• Correlates and impact of obsessive-compulsive comorbidity in bipolar disorder  Journal Articles
• Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group  Journal Articles
• Creatine supplementation and riluzole treatment provide similar beneficial effects in copper, zinc superoxide dismutase (G93A) transgenic mice  Journal Articles
• De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy  Journal Articles
• Determinants of delays in treatment initiation in children and adolescents diagnosed with leukemia or lymphoma in Canada  Journal Articles
• Development and Validation of SDBeasy Score as a Predictor of Behavioral Outcomes in Childhood  Journal Articles
• Differences between unipolar mania and bipolar‐I disorder: Evidence from nine epidemiological studies  Journal Articles
• Differences in health, participation and life satisfaction outcomes in adults following paediatric- versus adult-sustained spinal cord injury  Journal Articles
• Disability and Health-related Quality of Life in Long-term Survivors of Cancer in Childhood in Brazil  Journal Articles
• Does family history predict the age at onset of new breast cancers in BRCA1 and BRCA2 mutation‐positive families?  Journal Articles
• Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation  Journal Articles
• Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer  Journal Articles
• Early-Onset Developmental and Epileptic Encephalopathies of Infancy: An Overview of the Genetic Basis and Clinical Features  Journal Articles
• Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease  Journal Articles
• Epidemiology of Social Phobia in Later Life  Journal Articles
• Estimating the cost of lung cancer diagnosis and treatment in Canada: the POHEM model.  Journal Articles
• Evidence of linkage in subtypes of alcoholism  Journal Articles
• Examining early and late onset of multimorbidity in the Canadian Longitudinal Study on Aging  Journal Articles
• Exercise Not Asthma  Journal Articles
• Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction  Journal Articles
• Factors affecting postoperative stereopsis in acquired nonaccommodative esotropia  Journal Articles
• Female and male antisocial trajectories: From childhood origins to adult outcomes  Journal Articles
• Field trial for autistic disorder in DSM-IV  Journal Articles
• Genetics of early-onset coronary artery disease  Journal Articles
• Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants  Journal Articles
• Genotypes of chronic progressive external ophthalmoplegia in a large adult-onset cohort  Journal Articles
• HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome  Journal Articles
• Health-related Quality of Life in Long-term Survivors of Brain Tumors in Childhood and Adolescence  Journal Articles
• Hepatic Lipase Deficiency Delays Atherosclerosis, Myocardial Infarction, and Cardiac Dysfunction and Extends Lifespan in SR-BI/Apolipoprotein E Double Knockout Mice  Journal Articles
• Hepatoblastoma in a Child With Early-onset Cirrhosis  Journal Articles
• Hereditary risk factors for the development of gastric cancer in younger patients  Journal Articles
• Heterogeneity in presentation and treatment of catamenial anaphylaxis  Journal Articles
• Hoarding: A meta‐analysis of age of onset  Journal Articles
• Hyperhomocysteinemia as a cause of premature stroke in a young patient  Journal Articles
• IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies  Journal Articles
• IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies.  Journal Articles
• IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis  Journal Articles
• Illness burden and medical comorbidity in the Systematic Treatment Enhancement Program for Bipolar Disorder  Journal Articles
• Imaging Predictors of Neurologic Outcome After Pediatric Arterial Ischemic Stroke  Journal Articles
• Impact of Comorbid Anxiety Disorders on Outcome in a Cohort of Patients With Bipolar Disorder  Journal Articles
• Impact of sunlight on the age of onset of bipolar disorder  Journal Articles
• Implicit and explicit alcohol-related motivations among college binge drinkers  Journal Articles
• Incidence and Remission of Nocturia: A Systematic Review and Meta-analysis  Journal Articles
• Incidence of new-onset diabetes mellitus and association with mortality in childhood solid organ transplant recipients: a population-based study  Journal Articles
• Infantile-Onset Syndromic Cerebellar Ataxia and CACNA1G Mutations  Journal Articles
• Influence of birth cohort on age of onset cluster analysis in bipolar I disorder  Journal Articles
• Influence of light exposure during early life on the age of onset of bipolar disorder  Journal Articles
• Interaction between SLC6A4 promoter variants and childhood trauma on the age at onset of bipolar disorders  Journal Articles
• Interventions for cutaneous disease in systemic lupus erythematosus  Journal Articles
• Italian Registry of Haemophilia and Allied Disorders. Objectives, methodology and data analysis  Journal Articles
• Juvenile onset of Crohn's disease: A risk factor for reduced lumbar bone mass in premenopausal women  Journal Articles
• Late onset mania in the elderly  Journal Articles
• Late-Onset Adrenoleukodystrophy Associated With Long-Standing Psychiatric Symptoms  Journal Articles
• Late-onset Tay-Sachs disease presenting as catatonic schizophrenia: diagnostic and treatment issues.  Journal Articles
• Lessons from a multicenter, international, large sample size analysis of patients with obsessive–compulsive disorders: an overview of the ICOCS Snapshot studies  Journal Articles
• Lifetime Prevalence of Mental Disorders in U.S. Adolescents: Results from the National Comorbidity Survey Replication–Adolescent Supplement (NCS-A)  Journal Articles
• Long-Term Follow-up of Asthma  Journal Articles
• Long-term seizure and social outcomes following temporal lobe surgery for intractable epilepsy during childhood  Journal Articles
• Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and Premature Death in Apolipoprotein E–Deficient Mice  Journal Articles
• Mammographic features of pure mucinous carcinoma of the breast with pathological correlation.  Journal Articles
• Manifestaciones iniciales de los trastornos del espectro autista. Experiencia en 393 casos atendidos en un centro neurológico infantil  Journal Articles
• Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease  Journal Articles
• Moderators of Naltrexone’s Effects on Drinking, Urge, and Alcohol Effects in Non‐Treatment‐Seeking Heavy Drinkers in the Natural Environment  Journal Articles
• Mortality rates and causes of death among all HIV-positive individuals with hemophilia in Canada over 21 years of follow-up  Journal Articles
• Mutations in KCNT1 cause a spectrum of focal epilepsies  Journal Articles
• Myasthenia gravis: A study from India  Journal Articles
• Myopia and Early-Onset Type 2 Diabetes: A Nationwide Cohort Study  Journal Articles
• No Association between the 20210 G/A Prothrombin Gene Mutation and Premature Coronary Artery Disease  Journal Articles
• Novel GAA sequence variant c.1211 A>G reduces enzyme activity but not protein expression in infantile and adult onset Pompe disease  Journal Articles
• Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure  Journal Articles
• Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy  Journal Articles
• Obsessive-compulsive disorder (OCD): is this disorder under-recognized?  Journal Articles
• Obsessive-compulsive disorder in the elderly: A report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)  Journal Articles
• Ovarian Failure Related to Eukaryotic Initiation Factor 2B Mutations  Journal Articles
• Overweight and incident hypertension: does age of onset matter?  Journal Articles
• Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: The Canadian Healthy Infant Longitudinal Development Birth Cohort Study  Journal Articles
• Pediatric modification of the Montreal classification for inflammatory bowel disease  Journal Articles
• Pediatric superior vena cava syndrome: An evidence‐based systematic review of the literature  Journal Articles
• Perinatal Exposures and Breast Cancer Risk in the Western New York Exposures and Breast Cancer (WEB) Study  Journal Articles
• Perinatal factors as risk factors of bipolar disorder onset in young adulthood: a 22-year birth cohort  Conferences
• Phenotypes of sleep-disordered breathing symptoms to two years of age based on age of onset and duration of symptoms  Journal Articles
• Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative.  Journal Articles
• Physical Activity in Long-term Survivors of Acute Lymphoblastic Leukemia in Childhood and Adolescence: A Cross-sectional Cohort Study  Journal Articles
• Plasma Ghrelin and Risks of Sex-Specific, Site-Specific, and Early-Onset Colorectal Cancer: A Mendelian Randomization Analysis.  Journal Articles
• Polypharmacy and suicide attempts in bipolar disorder  Journal Articles
• Prediction of Differential Adult Health Burden by Conduct Problem Subtypes in Males  Journal Articles
• Predictors of Response in Generalized Social Phobia  Journal Articles
• Predominant polarity in bipolar disorder: Diagnostic implications  Journal Articles
• Presentation and Disease Course of Childhood‐Onset Versus Adult‐Onset Takayasu Arteritis  Journal Articles
• Prevalence of Hypertension and Albuminuria in Pediatric Type 2 Diabetes  Journal Articles
• Prevalence of new-onset vestibular symptoms following cochlear implantation.  Journal Articles
• Prevalence of pyridoxine dependent seizures in south Indian children with early onset intractable epilepsy: A hospital based prospective study  Journal Articles
• Primary angiitis of the CNS diagnosed by angiography  Journal Articles
• Primary early onset dysthymia, biochemical correlates of the therapeutic response to fluoxetine: II. Urinary metabolites of serotonin, norepinephrine, epinephrine and melatonin  Journal Articles
• Psychiatric and clinical correlates of rapid cycling bipolar disorder: a cross-sectional study  Journal Articles
• Quality care in seniors with new‐onset rheumatoid arthritis: A Canadian perspective  Journal Articles
• Recommendations for future research in relation to pediatric pulmonary embolism: communication from the SSC of the ISTH  Journal Articles
• Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus  Journal Articles
• Relationship between sunlight and the age of onset of bipolar disorder: An international multisite study  Journal Articles
• Relationship of Childhood Sexual and Physical Abuse to Anxiety Disorders  Journal Articles
• Relevance of Birth Cohorts to Assessment of Asthma Persistence  Journal Articles
• Reports of abnormal cervical cancer screening tests in systemic sclerosis  Journal Articles
• Risk Factors for Airway Remodeling in Asthma Manifested by a Low Postbronchodilator FEV₁/Vital Capacity Ratio  Journal Articles
• Risk factors for health‐related quality of life in children with epilepsy: A meta‐analysis  Journal Articles
• Screening for Cognitive Impairment in General Practice  Journal Articles
• Self‐reported quality of life and degree of youth‐parent agreement: A long‐term follow‐up of childhood‐onset epilepsy  Journal Articles
• Serum brain-derived neurotrophic factor in patients with trauma psychopathology  Journal Articles
• Sex Differences in Factors Associated with Childhood- and Adolescent-Onset Wheeze  Journal Articles
• Similarities in serum oxidative stress markers and inflammatory cytokines in patients with overt schizophrenia at early and late stages of chronicity  Journal Articles
• Solar insolation in springtime influences age of onset of bipolar I disorder  Journal Articles
• Staging bipolar disorder: clinical, biochemical, and functional correlates  Journal Articles
• Substantial practice variation exists in the management of childhood nephrotic syndrome  Journal Articles
• The Course of Asthma in Churg–Strauss Syndrome  Journal Articles
• The Magnetic Resonance Imaging Appearance of Monophasic Acute Disseminated Encephalomyelitis  Journal Articles
• The Neuropsychiatry of Adult-Onset Adrenoleukodystrophy  Journal Articles
• The Position of the Polycystic Kidney Disease 1 (PKD1) Gene Mutation Correlates with the Severity of Renal Disease  Journal Articles
• The Relationship Between Childhood Physical Abuse and Suicidality Among Depressed Women: Results From a Community Sample  Journal Articles
• The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy  Journal Articles
• The hereditary adult-onset ataxias in South Africa  Journal Articles
• The influence of age at onset and duration of illness on long-term outcome in patients with obsessive-compulsive disorder: A report from the International College of Obsessive Compulsive Spectrum Disorders (ICOCS)  Journal Articles
• The multiple facets of pulmonary sequestration  Conferences
• The mutational landscape of normal human endometrial epithelium  Journal Articles
• The need for inclusion of sex and age of onset variables in genetic association studies of obsessive–compulsive disorder: Overview  Journal Articles
• Toward the Cure of All Children With Cancer Through Collaborative Efforts: Pediatric Oncology As a Global Challenge  Journal Articles
• Validation of the Symptom Screening in Pediatrics Tool in Children Receiving Cancer Treatments  Journal Articles
• What Causes Premature Coronary Artery Disease?  Journal Articles