Age of Onset Concept

subject area of

• 50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis  Academic Article
• A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function  Academic Article
• A Longitudinal, Population-Based, Cohort Study of Childhood Asthma Followed to Adulthood  Academic Article
• A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors  Academic Article
• A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors  Academic Article
• A heteroplasmic mitochondrial complex I gene mutation in adult-onset dystonia  Academic Article
• A large-scale candidate gene association study of age at menarche and age at natural menopause  Academic Article
• A mitochondrial disorder with ptosis and exercise intolerance without ophthalmoparesis secondary to m.5865 T > C variant  Academic Article
• A new highly penetrant form of obesity due to deletions on chromosome 16p11.2  Academic Article
• A novel homozygous GALC mutation: Very early onset and rapidly progressive Krabbe disease  Academic Article
• A systematic review of integrative clinical trials for supportive care in pediatric oncology: a report from the International Society of Pediatric Oncology, T&CM collaborative  Academic Article
• Access to essential medicines for children with cancer: a joint SIOP-CCI position statement  Academic Article
• Acute myelogenous leukemia in adolescents and young adults  Academic Article
• Adjuvant Treatment and Onset of Menopause Predict Weight Gain After Breast Cancer Diagnosis  Academic Article
• Adolescent Nonalcoholic Fatty Liver Disease and Type 2 Diabetes in Young Adulthood  Academic Article
• Adolescent Obesity and Early-Onset Type 2 Diabetes  Academic Article
• Adults with Mood Disorders Have an Increased Risk Profile for Cardiovascular Disease within the First 2 Years of Treatment  Academic Article
• Advances in the molecular classification of pediatric brain tumors: a guide to the galaxy  Academic Article
• Age of First Faint in Patients with Vasovagal Syncope  Academic Article
• Age of onset of recurrent respiratory papillomatosis: a distribution analysis  Academic Article
• Age-of-Onset Classification of Conduct Disorder: Reliability and Validity in a Prospective Cohort Study  Academic Article
• Age-related variables in childhood epilepsy: How do they relate to each other and to quality of life?  Academic Article
• Alternate forms of logical memory and verbal fluency tasks for repeated testing in early cognitive changes  Academic Article
• Alzheimer’s and other dementias in Canada, 2011 to 2031: a microsimulation Population Health Modeling (POHEM) study of projected prevalence, health burden, health services, and caregiving use  Academic Article
• An Open Trial of Topiramate in the Treatment of Generalized Social Phobia  Academic Article
• Analysis of Environmental Factors in Familial Versus Sporadic Paget's Disease of Bone-The New England Registry for Paget's Disease of Bone  Academic Article
• Anterior Cingulate Volumes in Never-Treated Patients with Major Depressive Disorder  Academic Article
• Are there differences between young- and older-onset early inflammatory arthritis and do these impact outcomes? An analysis from the CATCH cohort  Academic Article
• Association between age at disease onset of anti-neutrophil cytoplasmic antibody–associated vasculitis and clinical presentation and short-term outcomes  Academic Article
• Association between solar insolation and a history of suicide attempts in bipolar I disorder  Academic Article
• Association of interleukin-10 levels with age of onset and duration of illness in patients with major depressive disorder  Academic Article
• Associations Between Methotrexate Use and the Risk of Cardiovascular Events in Patients with Elderly-onset Rheumatoid Arthritis  Academic Article
• Bipolar disorder and tobacco smoking: Categorical and dimensional clinical correlates in subjects from the Brazilian bipolar research network  Academic Article
• Birth-cohort and dual diagnosis effects on age-at-onset in Brazilian patients with bipolar I disorder  Academic Article
• Brain type carnosinase in dementia: a pilot study  Academic Article
• Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder  Academic Article
• Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample  Academic Article
• Cardiovascular Disease in South Asian Migrants  Academic Article
• Changes in cortical thickness across the lifespan in major depressive disorder  Academic Article
• Childhood Pancreatitis and Risk for Incident Diabetes in Adulthood  Academic Article
• Childhood maltreatment and DSM-IV adult mental disorders: Comparison of prospective and retrospective findings  Academic Article
• Childhood, adolescent and adult age at onset and related clinical correlates in obsessive–compulsive disorder: a report from the International College of Obsessive–Compulsive Spectrum Disorders (ICOCS)  Academic Article
• Chronic Immune Thrombocytopenic Purpura in Children  Academic Article
• Classification schemes for tumors diagnosed in adolescents and young adults  Academic Article
• Clinical delineation of myasthenia gravis in the Kingdom of Bahrain  Academic Article
• Clinical impact of late diagnose of bipolar disorder  Academic Article
• Clinical implications of a staging model for bipolar disorders  Academic Article
• Clinical spectrum of the pseudotumor cerebri in children: Etiological, clinical features, treatment and prognosis  Academic Article
• Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood  Academic Article
• Colorectal cancer in adolescents and young adults: Defining a growing threat  Academic Article
• Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease  Academic Article
• Comparative Effectiveness of Mycophenolate Mofetil for the Treatment of Juvenile‐Onset Proliferative Lupus Nephritis  Academic Article
• Complex two-gene modulation of lung disease severity in children with cystic fibrosis  Academic Article
• Coronary artery disease surveillance among childhood, adolescent and young adult cancer survivors: A systematic review and recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group  Academic Article
• Correlates and impact of obsessive-compulsive comorbidity in bipolar disorder  Academic Article
• Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group  Academic Article
• Creatine supplementation and riluzole treatment provide similar beneficial effects in copper, zinc superoxide dismutase (G93A) transgenic mice  Academic Article
• De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy  Academic Article
• Determinants of delays in treatment initiation in children and adolescents diagnosed with leukemia or lymphoma in Canada  Academic Article
• Development and Validation of SDBeasy Score as a Predictor of Behavioral Outcomes in Childhood  Academic Article
• Diagnosis of Huntington disease: A model for the stages of psychological response based on experience of a predictive testing program  Academic Article
• Differences between unipolar mania and bipolar‐I disorder: Evidence from nine epidemiological studies  Academic Article
• Differences in health, participation and life satisfaction outcomes in adults following paediatric- versus adult-sustained spinal cord injury  Academic Article
• Disability and Health-related Quality of Life in Long-term Survivors of Cancer in Childhood in Brazil  Academic Article
• Disease Variant Landscape of a Large Multiethnic Population of Moyamoya Patients by Exome Sequencing  Academic Article
• Does family history predict the age at onset of new breast cancers inBRCA1andBRCA2mutation-positive families?  Academic Article
• Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation  Academic Article
• Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer  Academic Article
• EARLY-LIFE PREDICTORS OF INTERNALIZING SYMPTOM TRAJECTORIES IN CANADIAN CHILDREN  Academic Article
• Early-Onset Developmental and Epileptic Encephalopathies of Infancy: An Overview of the Genetic Basis and Clinical Features  Academic Article
• Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease  Academic Article
• Efficacy of a Long-Acting Growth Hormone (GH) Preparation in Patients with Adult GH Deficiency  Academic Article
• Epidemiology of Social Phobia in Later Life  Academic Article
• Evidence of linkage in subtypes of alcoholism  Academic Article
• Examining early and late onset of multimorbidity in the Canadian Longitudinal Study on Aging  Academic Article
• Exercise Not Asthma  Academic Article
• Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction  Academic Article
• Factors affecting postoperative stereopsis in acquired nonaccommodative esotropia  Academic Article
• Factors contributing to the duration of untreated psychosis  Academic Article
• Female and male antisocial trajectories: From childhood origins to adult outcomes  Academic Article
• Field trial for autistic disorder in DSM-IV  Academic Article
• Genetics of early-onset coronary artery disease  Academic Article
• Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants  Academic Article
• Genotypes of chronic progressive external ophthalmoplegia in a large adult-onset cohort  Academic Article
• HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome  Academic Article
• Health-related Quality of Life in Long-term Survivors of Brain Tumors in Childhood and Adolescence  Academic Article
• Hepatic Lipase Deficiency Delays Atherosclerosis, Myocardial Infarction, and Cardiac Dysfunction and Extends Lifespan in SR-BI/Apolipoprotein E Double Knockout Mice  Academic Article
• Hepatoblastoma in a Child With Early-onset Cirrhosis  Academic Article
• Hereditary risk factors for the development of gastric cancer in younger patients  Academic Article
• Heterogeneity in presentation and treatment of catamenial anaphylaxis  Academic Article
• Hyperhomocysteinemia as a cause of premature stroke in a young patient  Academic Article
• IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies  Academic Article
• IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies.  Academic Article
• IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis  Academic Article
• Illness burden and medical comorbidity in the Systematic Treatment Enhancement Program for Bipolar Disorder  Academic Article
• Imaging Predictors of Neurologic Outcome After Pediatric Arterial Ischemic Stroke  Academic Article
• Impact of Comorbid Anxiety Disorders on Outcome in a Cohort of Patients With Bipolar Disorder  Academic Article
• Impact of sunlight on the age of onset of bipolar disorder  Academic Article
• Implicit and explicit alcohol-related motivations among college binge drinkers  Academic Article
• Incidence and Remission of Nocturia: A Systematic Review and Meta-analysis  Academic Article
• Incidence of new-onset diabetes mellitus and association with mortality in childhood solid organ transplant recipients: a population-based study  Academic Article
• Infantile-Onset Syndromic Cerebellar Ataxia and CACNA1G Mutations  Academic Article
• Influence of birth cohort on age of onset cluster analysis in bipolar I disorder  Academic Article
• Influence of light exposure during early life on the age of onset of bipolar disorder  Academic Article
• Interaction between SLC6A4 promoter variants and childhood trauma on the age at onset of bipolar disorders  Academic Article
• Interventions for cutaneous disease in systemic lupus erythematosus  Academic Article
• Italian Registry of Haemophilia and Allied Disorders. Objectives, methodology and data analysis  Academic Article
• Juvenile onset of Crohn's disease: A risk factor for reduced lumbar bone mass in premenopausal women  Academic Article
• Late onset mania in the elderly  Academic Article
• Late-Onset Adrenoleukodystrophy Associated With Long-Standing Psychiatric Symptoms  Academic Article
• Late-onset Tay-Sachs disease presenting as catatonic schizophrenia: diagnostic and treatment issues.  Academic Article
• Lifetime Prevalence of Mental Disorders in U.S. Adolescents: Results from the National Comorbidity Survey Replication–Adolescent Supplement (NCS-A)  Academic Article
• Long-Term Follow-up of Asthma  Academic Article
• Long-term seizure and social outcomes following temporal lobe surgery for intractable epilepsy during childhood  Academic Article
• Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and Premature Death in Apolipoprotein E–Deficient Mice  Academic Article
• Mammographic features of pure mucinous carcinoma of the breast with pathological correlation.  Academic Article
• Manifestaciones iniciales de los trastornos del espectro autista. Experiencia en 393 casos atendidos en un centro neurológico infantil  Academic Article
• Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease  Academic Article
• Moderators of Naltrexone’s Effects on Drinking, Urge, and Alcohol Effects in Non-Treatment-Seeking Heavy Drinkers in the Natural Environment  Academic Article
• Mood disorder service genetic database: Morbidity risks for mood disorders in 3,942 first-degree relatives of 671 index cases with single depression, recurrent depression, bipolar I, or bipolar II  Academic Article
• Mortality rates and causes of death among all HIV-positive individuals with hemophilia in Canada over 21 years of follow-up  Academic Article
• Mutations inKCNT1cause a spectrum of focal epilepsies  Academic Article
• Myasthenia gravis: A study from India  Academic Article
• Myopia and Early-Onset Type 2 Diabetes: A Nationwide Cohort Study  Academic Article
• No Association between the 20210 G/A Prothrombin Gene Mutation and Premature Coronary Artery Disease  Academic Article
• Novel GAA sequence variant c.1211 A>G reduces enzyme activity but not protein expression in infantile and adult onset Pompe disease  Academic Article
• Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure  Academic Article
• Obsessive-compulsive disorder (OCD): is this disorder under-recognized?  Academic Article
• Obsessive-compulsive disorder in the elderly: A report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)  Academic Article
• Ovarian Failure Related to Eukaryotic Initiation Factor 2B Mutations  Academic Article
• Overweight and incident hypertension: does age of onset matter?  Academic Article
• Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: The Canadian Healthy Infant Longitudinal Development Birth Cohort Study  Academic Article
• Pediatric modification of the Montreal classification for inflammatory bowel disease  Academic Article
• Pediatric superior vena cava syndrome: An evidence‐based systematic review of the literature  Academic Article
• Perinatal Exposures and Breast Cancer Risk in the Western New York Exposures and Breast Cancer (WEB) Study  Academic Article
• Phenotypes of sleep-disordered breathing symptoms to two years of age based on age of onset and duration of symptoms  Academic Article
• Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative.  Academic Article
• Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C→T (Arg493X) mutation: an international initiative  Academic Article
• Physical Activity in Long-term Survivors of Acute Lymphoblastic Leukemia in Childhood and Adolescence: A Cross-sectional Cohort Study  Academic Article
• Polypharmacy and suicide attempts in bipolar disorder  Academic Article
• Prediction of Differential Adult Health Burden by Conduct Problem Subtypes in Males  Academic Article
• Predictors of Response in Generalized Social Phobia  Academic Article
• Predominant polarity in bipolar disorder: Diagnostic implications  Academic Article
• Presentation and Disease Course of Childhood‐Onset Versus Adult‐Onset Takayasu Arteritis  Academic Article
• Prevalence and age of onset of Parkinson's disease in Cardiff: a community based cross sectional study and meta-analysis  Academic Article
• Prevalence of Hypertension and Albuminuria in Pediatric Type 2 Diabetes  Academic Article
• Prevalence of new-onset vestibular symptoms following cochlear implantation.  Academic Article
• Prevalence of pyridoxine dependent seizures in south Indian children with early onset intractable epilepsy: A hospital based prospective study  Academic Article
• Primary angiitis of the CNS diagnosed by angiography  Academic Article
• Primary early onset dysthymia, biochemical correlates of the therapeutic response to fluoxetine: II. Urinary metabolites of serotonin, norepinephrine, epinephrine and melatonin  Academic Article
• Psychiatric and clinical correlates of rapid cycling bipolar disorder: a cross-sectional study  Academic Article
• Quality care in seniors with new-onset rheumatoid arthritis: A Canadian perspective  Academic Article
• Recommendations for future research in relation to pediatric pulmonary embolism: communication from the SSC of the ISTH  Academic Article
• Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus  Academic Article
• Relationship between sunlight and the age of onset of bipolar disorder: An international multisite study  Academic Article
• Relationship of Childhood Sexual and Physical Abuse to Anxiety Disorders  Academic Article
• Relevance of Birth Cohorts to Assessment of Asthma Persistence  Academic Article
• Reports of abnormal cervical cancer screening tests in systemic sclerosis  Academic Article
• Risk Factors for Airway Remodeling in Asthma Manifested by a Low Postbronchodilator FEV₁/Vital Capacity Ratio  Academic Article
• Risk factors for health-related quality of life in children with epilepsy: A meta-analysis  Academic Article
• Screening for Cognitive Impairment in General Practice  Academic Article
• Self‐reported quality of life and degree of youth‐parent agreement: A long‐term follow‐up of childhood‐onset epilepsy  Academic Article
• Serum brain-derived neurotrophic factor in patients with trauma psychopathology  Academic Article
• Sex Differences in Factors Associated with Childhood- and Adolescent-Onset Wheeze  Academic Article
• Similarities in serum oxidative stress markers and inflammatory cytokines in patients with overt schizophrenia at early and late stages of chronicity  Academic Article
• Simplified Canadian Definition for Familial Hypercholesterolemia  Academic Article
• Solar insolation in springtime influences age of onset of bipolar I disorder  Academic Article
• Staging bipolar disorder: clinical, biochemical, and functional correlates  Academic Article
• Substantial practice variation exists in the management of childhood nephrotic syndrome  Academic Article
• The Course of Asthma in Churg–Strauss Syndrome  Academic Article
• The Magnetic Resonance Imaging Appearance of Monophasic Acute Disseminated Encephalomyelitis  Academic Article
• The Neuropsychiatry of Adult-Onset Adrenoleukodystrophy  Academic Article
• The Position of the Polycystic Kidney Disease 1 (PKD1) Gene Mutation Correlates with the Severity of Renal Disease  Academic Article
• The Relationship Between Childhood Physical Abuse and Suicidality Among Depressed Women: Results From a Community Sample  Academic Article
• The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy  Academic Article
• The hereditary adult-onset ataxias in South Africa  Academic Article
• The influence of age at onset and duration of illness on long-term outcome in patients with obsessive-compulsive disorder: A report from the International College of Obsessive Compulsive Spectrum Disorders (ICOCS)  Academic Article
• The motor phenotype of Parkinson's disease in relation to age at onset  Academic Article
• The motor phenotype of Parkinson's disease in relation to age at onset.  Academic Article
• The multiple facets of pulmonary sequestration  Conference Paper
• The need for inclusion of sex and age of onset variables in genetic association studies of obsessive–compulsive disorder: Overview  Academic Article
• Toward the Cure of All Children With Cancer Through Collaborative Efforts: Pediatric Oncology As a Global Challenge  Academic Article
• Validation of the Symptom Screening in Pediatrics Tool in Children Receiving Cancer Treatments  Academic Article
• Worsening of Symptoms Before Presentation with Vasovagal Syncope  Academic Article