Journal article
Genetics of early-onset coronary artery disease: from discovery to clinical translation.
Abstract
PURPOSE OF REVIEW: This review is a comprehensive update on recent discoveries on the genetics of early-onset coronary artery disease (EOCAD), and how those findings can be translated to advance its medical management.
RECENT FINDINGS: To date, a total of 266 common variants of modest effect size have been reported to be associated with CAD, but many still warrant functional studies. Rare variants impacting the function of at least 10 genes are …
Authors
Lali R; Cui E; Ansarikaleibari A; Pigeyre M; Paré G
Journal
Current Opinion in Cardiology, Vol. 34, No. 6, pp. 706–713
Publisher
Wolters Kluwer
Publication Date
November 2019
DOI
10.1097/hco.0000000000000676
ISSN
0268-4705