Interleukin-5
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A novel microbe-based treatment that attenuates the inflammatory profile in a mouse model of allergic airway disease Academic Article
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Allergen-Induced Increase in Airway Responsiveness, Airway Eosinophilia, and Bone-Marrow Eosinophil Progenitors in Mice Academic Article
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Allergen-induced Increases in Bone Marrow T Lymphocytes and Interleukin-5 Expression in Subjects with Asthma Academic Article
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Allergen-induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of haemopoietic progenitor cells in allergic inflammation Academic Article
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Amelioration of ovalbumin-induced allergic airway disease following Der p 1 peptide immunotherapy is not associated with induction of IL-35 Academic Article
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Anti-allergic therapies: effects on eosinophil progenitors Academic Article
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Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for people with asthma Academic Article
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Anti–IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics Academic Article
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Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma Academic Article
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Bone marrow contribution to eosinophilic inflammation Conference Paper
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Bone marrow in atopy and asthma: hematopoietic mechanisms in allergic inflammation Academic Article
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CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors Academic Article
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Cigarette Smoke Differentially Affects Eosinophilia and Remodeling in a Model of House Dust Mite Asthma Academic Article
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Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia. Academic Article
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Clinical significance of measuring levels of sputum and serum ECP and serum IL-5 in bronchial asthma Conference Paper
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Compartmentalized transgene expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in mouse lung enhances allergic airways inflammation Academic Article
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Cord blood molecular biomarkers of eosinophilopoiesis: Kinetic analysis of GATA-1, MBP1 and IL-5Rα mRNA expression Academic Article
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Costimulation Through CD86 Is Involved in Airway Antigen-Presenting Cell and T Cell Responses to Allergen in Atopic Asthmatics Academic Article
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Cytokines or Their Antagonists for the Treatment of Asthma Academic Article
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Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study Academic Article
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Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils Academic Article
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Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice. Academic Article
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Early Intestinal Th1 Inflammation and Mucosal T Cell Recruitment During Acute Graft-Versus-Host Reaction Academic Article
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Effect of anti‐IL‐5 biologics on weight and body mass index Academic Article
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Effects of a cysteinyl leukotriene receptor antagonist on eosinophil recruitment in experimental allergic rhinitis Academic Article
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Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response Academic Article
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Efficacy and safety of reslizumab in patients with moderate to severe eosinophilic asthma Academic Article
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Enhanced Expression of GM-CSF in Differentiating Eosinophils of Atopic and Atopic Asthmatic Subjects Academic Article
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Eosinophilopoiesis in A Murine Model of Allergic Airway Eosinophilia: Involvement of Bone Marrow IL-5 and IL-5 Receptor α Academic Article
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Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis Academic Article
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Evaluation of Inducible Costimulator/B7-Related Protein-1 as a Therapeutic Target in a Murine Model of Allergic Airway Inflammation Academic Article
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Evaluation of peroxisome proliferator-activated receptor agonists on interleukin-5-induced eosinophil differentiation Academic Article
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Exacerbations of Severe Asthma While on Anti–IL-5 Biologics Academic Article
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Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics. Academic Article
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Fish Oil Supplementation in Pregnancy Modifies Neonatal Progenitors at Birth in Infants at Risk of Atopy Academic Article
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GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice. Academic Article
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Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation Academic Article
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Generation of experimental allergic airways inflammation in the absence of draining lymph nodes Academic Article
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Granulocyte Macrophage Colony–Stimulating Factor–Driven Respiratory Mucosal Sensitization Induces Th2 Differentiation and Function Independently of Interleukin-4 Academic Article
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Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures Academic Article
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Haemopoietic mechanisms in murine allergic upper and lower airway inflammation Academic Article
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Haemopoietic processes in allergic disease: eosinophil/basophil development Academic Article
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IL-5 contributes to worm expulsion and muscle hypercontractility in a primaryT. spiralisinfection Academic Article
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IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: Relationship to expression of allergic disease Academic Article
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Increased detection of interleukin-;5 in sputum by addition of protease inhibitors Academic Article
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Increased eosinophil-lineage committed progenitors in the lung of allergen-challenged mice Academic Article
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Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects. Academic Article
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Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia Academic Article
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Increased production of IL-5 and dominant Th2-type response in airways of Churg–Strauss syndrome patients Academic Article
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Increases in airway eosinophils and interleukin-5 with minimal bronchoconstriction during repeated low-dose allergen challenge in atopic asthmatics Academic Article
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Interactions of Hemopoietic Cytokines on Differentiation of HL-60 Cells Academic Article
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Interleukin (IL)-5 but Not Immunoglobulin E Reconstitutes Airway Inflammation and Airway Hyperresponsiveness in IL-4–Deficient Mice Academic Article
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Interleukin-4 and RANTES expression in maturing eosinophils derived from human cord blood CD34+progenitors Academic Article
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Interleukin-5 and allergic inflammation Academic Article
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Interleukin-5 deficient mice exhibit impaired host defence against challenge Trichinella spiralis infections Academic Article
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Interleukin-5 is a human basophilopoietin: induction of histamine content and basophilic differentiation of HL-60 cells and of peripheral blood basophil-eosinophil progenitors Academic Article
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Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects Academic Article
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Interleukin-8 is a chemo-attractant for eosinophils purified from subjects with a blood eosinophilia but not from normal healthy subjects Academic Article
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Intrinsic pathway of apoptosis in peripheral blood eosinophils of Churg–Strauss syndrome Academic Article
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Kinetics of Allergen-Induced Airway Eosinophilic Cytokine Production and Airway Inflammation Academic Article
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Kinetics of Bone Marrow Eosinophilopoiesis and Associated Cytokines after Allergen Inhalation Academic Article
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Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia Academic Article
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Modulation of Human Airway Smooth Muscle Migration by Lipid Mediators and Th-2 Cytokines Academic Article
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Monoclonal antibodies for the treatment of refractory asthma Academic Article
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Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4 Academic Article
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New treatment approaches for asthma Academic Article
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Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma Academic Article
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Novel targeted therapies for eosinophilic disorders Academic Article
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POINT: Will New Anti-eosinophilic Drugs Be Useful in Asthma Management? Yes Academic Article
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Pathogenesis of Murine Experimental Allergic Rhinitis: A Study of Local and Systemic Consequences of IL-5 Deficiency Academic Article
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Proliferation and release of IL-5 and IFN-γ by peripheral blood mononuclear cells from cat-allergic asthmatics and rhinitics, non–cat-allergic asthmatics, and normal controls to peptides derived from Fel d 1 chain 1 Academic Article
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Proteinase-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways Academic Article
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Reassessing the Th2 cytokine basis of asthma Academic Article
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Recombinant adenovirus vectors expressing interleukin-5 and -6 specifically enhance mucosal immunoglobulin A responses in the lung Academic Article
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Reduced amount of intestinal mucus by treatment with anti-CD4 antibody interferes with the spontaneous cure of Nippostrongylus brasiliensis-infection in mice Academic Article
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Regulation of IL–5 and IL–5 Receptor Expression in the Bone Marrow of Allergic Asthmatics Conference Paper
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Relationship between Sputum Eosinophilia and Sinus Disease in Patients with Eosinophilic Bronchitis Academic Article
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Reslizumab for Poorly Controlled, Eosinophilic Asthma Academic Article
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Sputum CD34+IL-5Rα+ Cells Increase after Allergen Academic Article
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Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena Academic Article
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Systemic aspects of allergic disease: the role of the bone marrow Academic Article
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The Demise of Anti–IL-5 for Asthma, or Not Academic Article
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The Effect of Pranlukast on Allergen-induced Bone Marrow Eosinophilopoiesis in Subjects with Asthma Academic Article
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The Effects of Intranasal Budesonide on Allergen-induced Production of Interleukin-5 and Eotaxin, Airways, Blood, and Bone Marrow Eosinophilia, and Eosinophil Progenitor Expansion in Sensitized Mice Academic Article
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The effects of intranasal budesonide on allergen-induced production of interleukin-5 and eotaxin, airways, blood, and bone marrow eosinophilia, and eosinophil progenitor expansion in sensitized mice Academic Article
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The effects of montelukast on tissue inflammatory and bone marrow responses in murine experimental allergic rhinitis: interaction with interleukin-5 deficiency Academic Article
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The lnterleukin-5/Receptor Interaction Activates Lyn and Jak2 Tyrosine Kinases and Propagates Signals via the Ras-Raf-1-MAP Kinase and the Jak-STAT Pathways in Eosinophils Conference Paper
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The trials and tribulations of IL-5, eosinophils, and allergic asthma Academic Article
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The trials and tribulations of anti–IL-5 … Academic Article
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Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma Academic Article
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Toll-like receptor-mediated eosinophil-basophil differentiation: autocrine signalling by granulocyte-macrophage colony-stimulating factor in cord blood haematopoietic progenitors Academic Article
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Type 2 Cytokines in the Pathogenesis of Sustained Airway Dysfunction and Airway Remodeling in Mice Academic Article