ErbB Receptors Concept

subject area of

• sli-3 Negatively Regulates the LET-23/Epidermal Growth Factor Receptor-Mediated Vulval Induction Pathway in Caenorhabditis elegans  Journal Articles
• A Mendelian Randomization-Based Approach to Identify Early and Sensitive Diagnostic Biomarkers of Disease  Journal Articles
• A Phase II Trial of Erlotinib and Concurrent Palliative Thoracic Radiation for Patients With Non–Small-Cell Lung Cancer  Journal Articles
• A biological staging model for operable non-small cell lung cancer  Journal Articles
• A phase I study of oral ZD 1839 given daily in patients with solid tumors: IND.122, a study of the Investigational New Drug Program of the National Cancer Institute of Canada Clinical Trials Group  Journal Articles
• A phase II study of ZD6474 (Zactima™), a selective inhibitor of VEGFR and EGFR tyrosine kinase in patients with relapsed multiple myeloma—NCIC CTG IND.145  Journal Articles
• A phase II study of erlotinib (OSI-774) given in combination with carboplatin in patients with recurrent epithelial ovarian cancer (NCIC CTG IND.149)  Journal Articles
• A phase II trial of ZD1839 (Iressa™) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer  Journal Articles
• A phase II trial of dacomitinib, an oral pan-human EGF receptor (HER) inhibitor, as first-line treatment in recurrent and/or metastatic squamous-cell carcinoma of the head and neck  Conferences
• Adjuvant Chemotherapy With or Without Biologics Including Antiangiogenics and Monoclonal Antibodies Targeting EGFR and EpCAM in Colorectal Cancer: A Systematic Review and Meta-analysis  Journal Articles
• Argos and Spitz group genes function to regulate midline glial cell number in Drosophila embryos  Journal Articles
• Association of Calcium, Phosphate and Parathyroid Hormone with Renal Allograft Function: A Retrospective Cohort Study  Journal Articles
• Association of Phosphorylated Epidermal Growth Factor Receptor with Survival in Patients with Locally Advanced Non-small Cell Lung Cancer Treated with Radiotherapy  Journal Articles
• Associations between insulin-like growth factors and their binding proteins and other prognostic indicators in breast cancer  Journal Articles
• BDNF/TrkB Content and Interaction with Gastrin-Releasing Peptide Receptor Blockade in Colorectal Cancer  Journal Articles
• Bcl-2 is an independent prognostic factor and adds to a biological model for predicting outcome in operable non-small cell lung cancer  Journal Articles
• Biology and patterns of response to EGFR-inhibition in squamous cell cancers of the lung and head & neck  Journal Articles
• Caveolin-1 phosphorylation is required for stretch-induced EGFR and Akt activation in mesangial cells  Journal Articles
• Cetuximab in Metastatic Squamous Cell Cancer of the Skin: A Swiss Case Series  Journal Articles
• Challenges to Implementation of an Epidermal Growth Factor Receptor Testing Strategy for Non–Small-Cell Lung Cancer in a Publicly Funded Health Care System  Journal Articles
• Clinical impact of mutation fraction in epidermal growth factor receptor mutation positive NSCLC patients  Journal Articles
• Coexpression of epidermal growth factor receptor with related factors is associated with a poor prognosis in non-small-cell lung cancer  Journal Articles
• Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells  Journal Articles
• Cost-effectiveness of Osimertinib as a Second-line Treatment in Patients With EGFR-mutated Advanced Non–Small Cell Lung Cancer in China  Journal Articles
• Cyclooxygenase-2 protein levels are independent of epidermal growth factor receptor expression or activation in operable non-small cell lung cancer  Journal Articles
• Dacomitinib compared with placebo in pretreated patients with advanced or metastatic non-small-cell lung cancer (NCIC CTG BR.26): a double-blind, randomised, phase 3 trial  Journal Articles
• Does the Addition of Biologic Agents to Chemotherapy in Patients with Unresectable Colorectal Cancer Metastases Result in a Higher Proportion of Patients Undergoing Resection? A Systematic Review and Meta-analysis  Journal Articles
• Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study  Journal Articles
• EGF Decreases the Abundance of MicroRNAs That Restrain Oncogenic Transcription Factors  Journal Articles
• EGFR-PLCγ1 signaling mediates high glucose-induced PKCβ1-Akt activation and collagen I upregulation in mesangial cells  Journal Articles
• Economic Analysis: Randomized Placebo-Controlled Clinical Trial of Erlotinib in Advanced Non-Small Cell Lung Cancer  Journal Articles
• Epidermal Growth Factor Receptor and Transforming Growth Factor-β Signaling Contributes to Variation for Wing Shape in Drosophila melanogaster  Journal Articles
• Epidermal Growth Factor Receptor: Pathway, Therapies, and Pipeline  Journal Articles
• Epidermal growth factor receptor deficiency: Expanding the phenotype beyond infancy  Journal Articles
• Epidermal growth factor receptor-dependent activation of Gab1 is involved in ErbB-2-mediated mammary tumor progression  Journal Articles
• Epidermal growth factor receptors and cyclooxygenase-2 in the pathogenesis of non-small cell lung cancer: potential targets for chemoprevention and systemic therapy  Journal Articles
• Erlotinib in Lung Cancer — Molecular and Clinical Predictors of Outcome  Journal Articles
• Evidence That the Epidermal Growth Factor Receptor on Host Cells Confers Reovirus Infection Efficiency  Journal Articles
• Expression of EGFR, HER-2/neu and KIT in germ cell tumours  Journal Articles
• Expression of c-erb B-2 oncogene product in persistent gestational trophoblastic disease  Journal Articles
• Fluorescence in situ hybridization gene amplification analysis of EGFR and HER2 in patients with malignant salivary gland tumors treated with lapatinib  Journal Articles
• Genetic analysis of <i>vein</i> function in the <i>Drosophila</i> embryonic nervous system  Journal Articles
• Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model  Journal Articles
• HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells  Journal Articles
• HSF-1/miR-145-5p transcriptional axis enhances hyperthermic intraperitoneal chemotherapy efficacy on peritoneal ovarian carcinosis  Journal Articles
• High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells  Journal Articles
• High-Grade Glioma Formation Results from Postnatal Pten Loss or Mutant Epidermal Growth Factor Receptor Expression in a Transgenic Mouse Glioma Model  Journal Articles
• Hypoxia‐inducible factor‐1α in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways  Journal Articles
• Identification of a Low-Risk Luminal A Breast Cancer Cohort That May Not Benefit From Breast Radiotherapy  Journal Articles
• Immunofluorometric analysis of p53 protein and prostate-specific antigen in breast tumours and their association with other prognostic indicators  Journal Articles
• Mechanical Strain-Induced RhoA Activation Requires NADPH Oxidase-Mediated ROS Generation in Caveolae  Journal Articles
• Mechanical stretch-induced RhoA activation is mediated by the RhoGEF Vav2 in mesangial cells  Journal Articles
• MicroRNA Signature in Metastatic Colorectal Cancer Patients Treated With Anti-EGFR Monoclonal Antibodies  Journal Articles
• MicroRNA expression profiling of thymic epithelial tumors  Journal Articles
• MicroRNAs: Non-coding fine tuners of receptor tyrosine kinase signalling in cancer  Journal Articles
• Modern era systemic therapies: Expanding concepts of cure in early and locally advanced non‐small cell lung cancer  Journal Articles
• Multicenter, Randomized Phase II Trial of Oral CI-1033 for Previously Treated Advanced Ovarian Cancer  Journal Articles
• Nivolumab in Combination With Platinum‐Based Doublet Chemotherapy for First-Line Treatment of Advanced Non–Small-Cell Lung Cancer  Journal Articles
• Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer  Journal Articles
• Nuclear transportation of exogenous epidermal growth factor receptor and androgen receptor via extracellular vesicles  Journal Articles
• Nucleotide Variation in the Egfr Locus of Drosophila melanogaster  Journal Articles
• Origin and Differentiation of Supernumerary Midline Glia inDrosophilaEmbryos Deficient for Apoptosis  Journal Articles
• Osimertinib in UntreatedEGFR-Mutated Advanced Non–Small-Cell Lung Cancer  Journal Articles
• Ovarian Thecal/Interstitial Cells Produce an Epidermal Growth Factor-Like Substance*  Journal Articles
• Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC  Journal Articles
• PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells  Journal Articles
• Parathyroid hormone-related protein induces fibronectin up-regulation in rat mesangial cells through reactive oxygen species/Src/EGFR signaling  Journal Articles
• Peptide Growth Factors Modulate Prostaglandin E and F Production by Goldfish Ovarian Follicles  Journal Articles
• Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non–Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations  Journal Articles
• Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors  Journal Articles
• Phase I Targeted Combination Trial of Sorafenib and Erlotinib in Patients with Advanced Solid Tumors  Journal Articles
• Phase I/II Trial of Erlotinib and Cisplatin in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: A Princess Margaret Hospital Phase II Consortium and National Cancer Institute of Canada Clinical Trials Group Study  Conferences
• Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer  Journal Articles
• Pooled Analysis of the Prognostic and Predictive Value of KRAS Mutation Status and Mutation Subtype in Patients with Non–Small Cell Lung Cancer Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors  Journal Articles
• Potential indicators of radiosensitivity in squamous cell carcinoma of the head and neck  Journal Articles
• Preclinical evaluation of a new liposomal formulation of cisplatin, lipoplatin, to treat cisplatin-resistant cervical cancer  Journal Articles
• Predicting response to EGFR-tyrosine kinase inhibitors among diverse ancestries: Just way too polymorphic  Journal Articles
• Predictive and Pharmacodynamic Biomarker Studies in Tumor and Skin Tissue Samples of Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Treated With Erlotinib  Journal Articles
• Promising response of dabrafenib, trametinib, and osimertinib combination therapy for concomitant BRAF and EGFR-TKI resistance mutations  Journal Articles
• Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation  Journal Articles
• Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal Cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 Trial  Journal Articles
• Protein kinase Cα negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor  Journal Articles
• Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck  Journal Articles
• Recognition of the Epidermal Growth Factor Receptor by Reovirus  Journal Articles
• Regulation of profibrotic responses by ADAM17 activation in high glucose requires its C-terminus and FAK  Journal Articles
• Replication of an Egfr-Wing Shape Association in a Wild-Caught Cohort of Drosophila melanogaster  Journal Articles
• Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis  Journal Articles
• Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial  Journal Articles
• SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells  Journal Articles
• SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis  Journal Articles
• SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells  Journal Articles
• Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811  Conferences
• Systemic Sclerosis Immunoglobulin Induces Growth and a Pro-Fibrotic State in Vascular Smooth Muscle Cells through the Epidermal Growth Factor Receptor  Journal Articles
• Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer  Journal Articles
• Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH  Journal Articles
• Targeting the epidermal growth factor receptor in non-small-cell lung cancer: Who, which, when, and how?  Journal Articles
• Tests for the replication of an association between Egfr and natural variation in Drosophila melanogaster wing morphology  Journal Articles
• The Inhibitory Control of Oocyte Maturation in the Zebrafish (Danio rerio): The Role of the G Protein-Coupled Estrogen Receptor and Epidermal Growth Factor  Journal Articles
• The Use of Systemic Treatment in the Maintenance of Patients with Non–Small Cell Lung Cancer: A Systematic Review  Journal Articles
• The p38-MK2-HuR pathway potentiates EGFRvIII–IL-1β-driven IL-6 secretion in glioblastoma cells  Journal Articles
• The sex-limited effects of mutations in the EGFR and TGF-β signaling pathways on shape and size sexual dimorphism and allometry in the Drosophila wing  Journal Articles
• Towards a biological staging model for operable non-small cell lung cancer  Journal Articles
• Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review.  Journal Articles
• rhomboid function in the midline of theDrosophila CNS  Journal Articles