Journal article
Clinical impact of mutation fraction in epidermal growth factor receptor mutation positive NSCLC patients
Abstract
Background:We examined clinical outcomes in a population-based cohort of EGFR mutant advanced NSCLC patients, exploring the potential role of factors including tumour EGFR mutation fraction and cellularity in predicting outcomes.Methods:A cohort of patients with EGFR mutant advanced NSCLC was identified (N=293); clinical outcomes, pathologic and treatment details were collected. Tumour response was determined from radiology and clinical notes. …
Authors
Martin P; Shiau CJ; Pasic M; Tsao M; Kamel-Reid S; Lin S; Tudor R; Cheng S; Higgins B; Burkes R
Journal
British Journal of Cancer, Vol. 114, No. 6, pp. 616–622
Publisher
Springer Nature
Publication Date
March 2016
DOI
10.1038/bjc.2016.22
ISSN
0007-0920