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Nuclear Kaiso Expression Is Associated with High...
Journal article

Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer

Abstract

Kaiso is a BTB/POZ transcription factor that is ubiquitously expressed in multiple cell types and functions as a transcriptional repressor and activator. Little is known about Kaiso expression and localization in breast cancer. Here, we have related pathological features and molecular subtypes to Kaiso expression in 477 cases of human invasive breast cancer. Nuclear Kaiso was predominantly found in invasive ductal carcinoma (IDC) (p = 0.007), …

Authors

Vermeulen JF; van de Ven RAH; Ercan C; van der Groep P; van der Wall E; Bult P; Christgen M; Lehmann U; Daniel J; van Diest PJ

Journal

PLOS ONE, Vol. 7, No. 5,

Publisher

Public Library of Science (PLoS)

Publication Date

2012

DOI

10.1371/journal.pone.0037864

ISSN

1932-6203