subject area of
- A High-Throughput Screen of the GTPase Activity of Escherichia coli EngA to Find an Inhibitor of Bacterial Ribosome Biogenesis Journal Articles
- A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia Journal Articles
- A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase Journal Articles
- A Sol−Gel-Derived Acetylcholinesterase Microarray for Nanovolume Small-Molecule Screening Journal Articles
- A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis Journal Articles
- A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium Journal Articles
- A new system for profiling drug-induced calcium signal perturbation in human embryonic stem cell-derived cardiomyocytes. Journal Articles
- A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors Journal Articles
- Action of Nitrofurans on E. Coli Journal Articles
- Advancing Novel Molecular Imaging Agents from Preclinical Studies to First-in-Humans Phase I Clinical Trials in Academia—A Roadmap for Overcoming Perceived Barriers Journal Articles
- An ESI‐MS/MS Method for Screening of Small‐Molecule Mixtures against Glycogen Synthase Kinase‐3β (GSK‐3β) Journal Articles
- An In Vitro Screen of Bacterial Lipopolysaccharide Biosynthetic Enzymes Identifies an Inhibitor of ADP-Heptose Biosynthesis Journal Articles
- Andexanet alfa for the treatment of hemorrhage Journal Articles
- Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance Journal Articles
- Bio-Solid-Phase Extraction/Tandem Mass Spectrometry for Identification of Bioactive Compounds in Mixtures Journal Articles
- Biosimilars for psoriasis: preclinical analytical assessment to determine similarity Journal Articles
- Bortezomib protects from varicose‐like venous remodeling Journal Articles
- COVID-19 clinical trials: learning from exceptions in the research chaos. Journal Articles
- Chemical Probes of Escherichia coli Uncovered through Chemical-Chemical Interaction Profiling with Compounds of Known Biological Activity Journal Articles
- Chemotherapy-Induced Neuropathy and Drug Discovery Platform Using Human Sensory Neurons Converted Directly from Adult Peripheral Blood Journal Articles
- Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy Journal Articles
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus Journal Articles
- Comparison of three cell-based drug screening platforms for HSV-1 infection Journal Articles
- Current models of pulmonary fibrosis for future drug discovery efforts Journal Articles
- Discovery of potent antiviral (HSV-1) quinazolinones and initial structure-activity relationship studies Journal Articles
- Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine Journal Articles
- Dissemination Bias in Systematic Reviews of Animal Research: A Systematic Review Journal Articles
- Diversity-Oriented Synthesis and Preliminary Biological Screening of Highly Substituted Five-Membered Lactones and Lactams Originating From an Allyboration of Aldehydes and Imines Journal Articles
- Effect of Interferon-γon Allergic Airway Responses in Interferon-γ–deficient Mice Journal Articles
- Effect of interferon-γ on allergic airway responses in interferon-γ-deficient mice Journal Articles
- Effects of oxygen free radicals and scavengers on the cardiac extracellular collagen matrix during ischemia-reperfusion. Journal Articles
- Effects of rosiglitazone on ovarian function and fertility in animals with reduced fertility following fetal and neonatal exposure to nicotine Journal Articles
- Ending COVID-19: progress and gaps in research—highlights of the July 2020 GloPID-R COVID-19 Research Synergies Meetings Journal Articles
- Exploration of Nonribosomal Peptide Families with an Automated Informatic Search Algorithm Journal Articles
- Functional Screening of Pharmacological Chaperones via Restoration of Enzyme Activity upon Denaturation Journal Articles
- Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice Journal Articles
- Guanosine Protects Glial Cells Against 6-Hydroxydopamine Toxicity Journal Articles
- Hepatocyte growth factor modulates the hepatic acute-phase response in thermally injured rats Journal Articles
- High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate Journal Articles
- High-Throughput Screening of Model Bacteria Journal Articles
- High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells Journal Articles
- Human type 5 adenovirus-based tuberculosis vaccine: is the respiratory route of delivery the future? Journal Articles
- Identification of Drug Candidates to Suppress Cigarette Smoke–induced Inflammation via Connectivity Map Analyses Journal Articles
- Identification of Pharmacological Chaperones for Gaucher Disease and Characterization of Their Effects on β‐Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry Journal Articles
- Identifying producers of antibacterial compounds by screening for antibiotic resistance Journal Articles
- Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds Journal Articles
- ImmunoDB: a web based tool to analyze preclinical data. Journal Articles
- Induced Pluripotent Stem Cells to Model and Treat Neurogenetic Disorders Journal Articles
- Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation Journal Articles
- Inhibition of exhaled nitric oxide production during sepsis does not prevent lung inflammation Journal Articles
- Inhibitor Screening Using Immobilized Enzyme Reactor Chromatography/Mass Spectrometry Journal Articles
- Inhibitor screening of pharmacological chaperones for lysosomal β-glucocerebrosidase by capillary electrophoresis Journal Articles
- Insulinlike Growth Factor I in Combination With Insulinlike Growth Factor Binding Protein 3 Affects the Hepatic Acute Phase Response and Hepatic Morphology in Thermally Injured Rats Journal Articles
- Invited Perspective: Screening in Academe: A Perspective on Implementation of University-Based Small Molecule Screening Journal Articles
- Is Heparin the Ideal Anticoagulant for Cardiopulmonary Bypass? Dermatan Sulphate May Be an Alternate Choice Journal Articles
- Justifying the number of animals for each experiment Journal Articles
- Lessons learned, challenges, and opportunities: The U.S. Endocrine Disruptor Screening Program Journal Articles
- Localization of heparin and low-molecular-weight heparin in the rat kidney Journal Articles
- Machine learning in preclinical drug discovery Journal Articles
- Measurement of both Cyclic [3H]AMP and Cyclic [3H]GMP in Cultured Vascular Smooth Muscle Cells Labeled with [3H]Hypoxanthine: Use in Studies of Cardiovascular Drugs Journal Articles
- Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes Journal Articles
- Metal-Induced Isomerization Yields an Intracellular Chelator that Disrupts Bacterial Iron Homeostasis Journal Articles
- Microfluidic devices for cell based high throughput screening Journal Articles
- Miniaturized Microfluidic Formats for Cell-Based High-Throughput Screening Journal Articles
- Mouse Models of Lung Fibrosis Journal Articles
- Mucosal damage during intestinal anaphylaxis in the rat Journal Articles
- NSAID-induced cyclooxygenase inhibition differentially depresses long-lasting versus brief synaptically-elicited responses of rat spinal dorsal horn neurons in vivo Journal Articles
- New Antithrombotics Journal Articles
- Not as fab as we thought Journal Articles
- Nutrient Stress Small-Molecule Screening Platform for Escherichia coli Journal Articles
- Observations on the Use of the Avian Chorioallantoic Membrane (CAM) Model in Investigations into Angiogenesis Journal Articles
- Omalizumab and the immune system: an overview of preclinical and clinical data Journal Articles
- Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance Journal Articles
- Peptide immunotherapy for allergic diseases Journal Articles
- Pharmacological Actions of Sulodexide Journal Articles
- Preclinical Studies on Mechanisms Underlying the Protective Effects of Propranolol in Traumatic Brain Injury: A Systematic Review Journal Articles
- Preclinical and Clinical Evidence of Antioxidant Effects of Antidepressant Agents: Implications for the Pathophysiology of Major Depressive Disorder Journal Articles
- Preclinical development of peptide vaccination combined with oncolytic MG1-E6E7 for HPV-associated cancer Journal Articles
- Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B Journal Articles
- Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: Examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia Journal Articles
- Protective effect of verapamil in experimental myocardial ischaemia: an electron microscopic investigation. Journal Articles
- Pulmonary structural maturation and pulmonary artery remodeling after reversible fetal ovine tracheal occlusion in diaphragmatic hernia Conferences
- Pyonitrins A–D: Chimeric Natural Products Produced by Pseudomonas protegens Journal Articles
- Recent Developments in Glioblastoma-On-A-Chip for Advanced Drug Screening Applications. Journal Articles
- Receptor subtypes mediating spinal cardiovascular effects of angiotensin II in rat using losartan and PD 123319 Journal Articles
- Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature Journal Articles
- Safety and efficiency of metered dose inhaler delivery of salbutamol in the intubated rabbit Journal Articles
- Salicylate improves macrophage cholesterol homeostasis via activation of Ampk Journal Articles
- Screening of Inhibitors Using Enzymes Entrapped in Sol−Gel-Derived Materials Journal Articles
- Selective Cyclooxygenase-2 Inhibitors as Potential Therapeutic Agents for Inflammatory Diseases Journal Articles
- Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165 Journal Articles
- Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids Journal Articles
- Selective suppression of rapid eye movement sleep (REMS) in cats by typical and atypical antidepressants. Journal Articles
- Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice Journal Articles
- Synthesis and Screening of a Library of Re/Tc-Based Amyloid Probes Derived from β-Breaker Peptides Journal Articles
- THE COMBINATION OF GROWTH HORMONE WITH HEPATOCYTE GROWTH FACTOR ALTERS THE ACUTE PHASE RESPONSE Journal Articles
- Targeting apoptosis: preclinical and early clinical experience with mapatumumab, an agonist monoclonal antibody targeting TRAIL-R1 Journal Articles
- The caveolin-1 regulated protein follistatin protects against diabetic kidney disease Journal Articles
- The complex task of measuring intestinal permeability in basic and clinical science Journal Articles
- The effects of montelukast on tissue inflammatory and bone marrow responses in murine experimental allergic rhinitis: interaction with interleukin‐5 deficiency Journal Articles
- The worm turns for antimicrobial discovery Journal Articles
- Ultrasound Imaging of Apoptosis: Spectroscopic Detection of DNA-Damage Effects In Vivo Journal Articles
- Unlocking the potential of natural products in drug discovery Journal Articles
- Vanadate, an inhibitor of stromelysin and collagenase expression, suppresses collagen induced arthritis. Journal Articles
- iPSC Technology: Platform for Drug Discovery Journal Articles