subject area of
- A High-Throughput Screen of the GTPase Activity of Escherichia coli EngA to Find an Inhibitor of Bacterial Ribosome Biogenesis Academic Article
- A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia Academic Article
- A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase Academic Article
- A Sol−Gel-Derived Acetylcholinesterase Microarray for Nanovolume Small-Molecule Screening Academic Article
- A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis Academic Article
- A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium Academic Article
- A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors Academic Article
- An ESI-MS/MS Method for Screening of Small-Molecule Mixtures against Glycogen Synthase Kinase-3β (GSK-3β) Academic Article
- An In Vitro Screen of Bacterial Lipopolysaccharide Biosynthetic Enzymes Identifies an Inhibitor of ADP-Heptose Biosynthesis Academic Article
- Andexanet alfa for the treatment of hemorrhage Academic Article
- Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance Academic Article
- Bio-Solid-Phase Extraction/Tandem Mass Spectrometry for Identification of Bioactive Compounds in Mixtures Academic Article
- Biosimilars for psoriasis: preclinical analytical assessment to determine similarity Academic Article
- Chemical Probes of Escherichia coli Uncovered through Chemical-Chemical Interaction Profiling with Compounds of Known Biological Activity Academic Article
- Chemotherapy-Induced Neuropathy and Drug Discovery Platform Using Human Sensory Neurons Converted Directly from Adult Peripheral Blood Academic Article
- Combination antifol therapy: observations on the development of resistant L1210 leukemic cells in vivo. Academic Article
- Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy Academic Article
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus Academic Article
- Comparison of three cell-based drug screening platforms for HSV-1 infection Academic Article
- Current models of pulmonary fibrosis for future drug discovery efforts Academic Article
- Discovery of potent antiviral (HSV-1) quinazolinones and initial structure-activity relationship studies Academic Article
- Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine Academic Article
- Dissemination Bias in Systematic Reviews of Animal Research: A Systematic Review Academic Article
- Diversity-Oriented Synthesis and Preliminary Biological Screening of Highly Substituted Five-Membered Lactones and Lactams Originating From an Allyboration of Aldehydes and Imines Academic Article
- Effect of Interferon-γon Allergic Airway Responses in Interferon-γ–deficient Mice Academic Article
- Effect of interferon-gamma on allergic airway responses in interferon-gamma-deficient mice Academic Article
- Effects of oxygen free radicals and scavengers on the cardiac extracellular collagen matrix during ischemia-reperfusion. Academic Article
- Effects of rosiglitazone on ovarian function and fertility in animals with reduced fertility following fetal and neonatal exposure to nicotine Academic Article
- Ending COVID-19: progress and gaps in research—highlights of the July 2020 GloPID-R COVID-19 Research Synergies Meetings Academic Article
- Exploration of Nonribosomal Peptide Families with an Automated Informatic Search Algorithm Academic Article
- Functional Screening of Pharmacological Chaperones via Restoration of Enzyme Activity upon Denaturation Academic Article
- Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice Academic Article
- Guanosine Protects Glial Cells Against 6-Hydroxydopamine Toxicity Academic Article
- Hepatocyte growth factor modulates the hepatic acute-phase response in thermally injured rats Academic Article
- High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate Academic Article
- High-Throughput Screening of Model Bacteria Academic Article
- High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells Academic Article
- Human type 5 adenovirus-based tuberculosis vaccine: is the respiratory route of delivery the future? Academic Article
- Identification of Drug Candidates to Suppress Cigarette Smoke–induced Inflammation via Connectivity Map Analyses Academic Article
- Identification of Pharmacological Chaperones for Gaucher Disease and Characterization of Their Effects on β-Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry Academic Article
- Identifying producers of antibacterial compounds by screening for antibiotic resistance Academic Article
- Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds Academic Article
- ImmunoDB: a web based tool to analyze preclinical data. Academic Article
- In Vitro Screening for Drug Repositioning Academic Article
- Induced Pluripotent Stem Cells to Model and Treat Neurogenetic Disorders Academic Article
- Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation Academic Article
- Inhibition of exhaled nitric oxide production during sepsis does not prevent lung inflammation Academic Article
- Inhibitor Screening Using Immobilized Enzyme Reactor Chromatography/Mass Spectrometry Academic Article
- Inhibitor screening of pharmacological chaperones for lysosomal β-glucocerebrosidase by capillary electrophoresis Academic Article
- Insulinlike Growth Factor I in Combination With Insulinlike Growth Factor Binding Protein 3 Affects the Hepatic Acute Phase Response and Hepatic Morphology in Thermally Injured Rats Academic Article
- Invited Perspective: Screening in Academe: A Perspective on Implementation of University-Based Small Molecule Screening Academic Article
- Is Heparin the Ideal Anticoagulant for Cardiopulmonary Bypass? Dermatan Sulphate May Be an Alternate Choice Academic Article
- Justifying the number of animals for each experiment Academic Article
- Lessons learned, challenges, and opportunities: The U.S. Endocrine Disruptor Screening Program Academic Article
- Localization of heparin and low-molecular-weight heparin in the rat kidney Academic Article
- Measurement of both Cyclic [3H]AMP and Cyclic [3H]GMP in Cultured Vascular Smooth Muscle Cells Labeled with [3H]Hypoxanthine: Use in Studies of Cardiovascular Drugs Academic Article
- Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes Academic Article
- Metal-Induced Isomerization Yields an Intracellular Chelator that Disrupts Bacterial Iron Homeostasis Academic Article
- Microfluidic devices for cell based high throughput screening Academic Article
- Miniaturized Microfluidic Formats for Cell-Based High-Throughput Screening Academic Article
- Mouse Models of Lung Fibrosis Academic Article
- Mucosal damage during intestinal anaphylaxis in the rat Academic Article
- NSAID-induced cyclooxygenase inhibition differentially depresses long-lasting versus brief synaptically-elicited responses of rat spinal dorsal horn neurons in vivo Academic Article
- New Antithrombotics Academic Article
- Not as fab as we thought Academic Article
- Nutrient Stress Small-Molecule Screening Platform for Escherichia coli Academic Article
- Observations on the Use of the Avian Chorioallantoic Membrane (CAM) Model in Investigations into Angiogenesis Academic Article
- Omalizumab and the immune system: an overview of preclinical and clinical data Academic Article
- Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance Academic Article
- Peptide immunotherapy for allergic diseases Academic Article
- Pharmacological Actions of Sulodexide Academic Article
- Pharmacological regulation of mediator release from human mast cells Academic Article
- Preclinical and Clinical Evidence of Antioxidant Effects of Antidepressant Agents: Implications for the Pathophysiology of Major Depressive Disorder Academic Article
- Preclinical development of peptide vaccination combined with oncolytic MG1-E6E7 for HPV-associated cancer Academic Article
- Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B Academic Article
- Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: Examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia Academic Article
- Protective effect of verapamil in experimental myocardial ischaemia: an electron microscopic investigation. Academic Article
- Pulmonary structural maturation and pulmonary artery remodeling after reversible fetal ovine tracheal occlusion in diaphragmatic hernia Conference Paper
- Rapid in vivo induction of leukocyte tissue factor mRNA and protein synthesis following low dose endotoxin administration to rabbits Academic Article
- Receptor subtypes mediating spinal cardiovascular effects of angiotensin II in rat using losartan and PD 123319 Academic Article
- Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature Academic Article
- Safety and efficiency of metered dose inhaler delivery of salbutamol in the intubated rabbit Academic Article
- Salicylate improves macrophage cholesterol homeostasis via activation of Ampk Academic Article
- Screening of Inhibitors Using Enzymes Entrapped in Sol−Gel-Derived Materials Academic Article
- Selective Cyclooxygenase-2 Inhibitors as Potential Therapeutic Agents for Inflammatory Diseases Academic Article
- Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165 Academic Article
- Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids Academic Article
- Selective suppression of rapid eye movement sleep (REMS) in cats by typical and atypical antidepressants. Academic Article
- Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice Academic Article
- Synthesis and Screening of a Library of Re/Tc-Based Amyloid Probes Derived from β-Breaker Peptides Academic Article
- THE COMBINATION OF GROWTH HORMONE WITH HEPATOCYTE GROWTH FACTOR ALTERS THE ACUTE PHASE RESPONSE Academic Article
- Targeting apoptosis: preclinical and early clinical experience with mapatumumab, an agonist monoclonal antibody targeting TRAIL-R1 Academic Article
- The caveolin-1 regulated protein follistatin protects against diabetic kidney disease Academic Article
- The clonogenic assay as a reproducible in vitro system to study predictive parameters of treatment outcome in acute nonlymphoblastic leukemia Academic Article
- The complex task of measuring intestinal permeability in basic and clinical science Academic Article
- The effects of montelukast on tissue inflammatory and bone marrow responses in murine experimental allergic rhinitis: interaction with interleukin-5 deficiency Academic Article
- The worm turns for antimicrobial discovery Academic Article
- Ultrasound Imaging of Apoptosis: Spectroscopic Detection of DNA-Damage Effects In Vivo Academic Article
- Unlocking the potential of natural products in drug discovery Academic Article
- Vanadate, an inhibitor of stromelysin and collagenase expression, suppresses collagen induced arthritis. Academic Article
- iPSC Technology: Platform for Drug Discovery Academic Article