Journal article
Recent Developments in Glioblastoma‐On‐A‐Chip for Advanced Drug Screening Applications
Abstract
Glioblastoma (GBM) is an aggressive form of cancer, comprising ≈80% of malignant brain tumors. However, there are no effective treatments for GBM due to its heterogeneity and the presence of the blood-brain barrier (BBB), which restricts the delivery of therapeutics to the brain. Despite in vitro models contributing to the understanding of GBM, conventional 2D models oversimplify the complex tumor microenvironment. Organ-on-a-chip (OoC) models …
Authors
Maity S; Bhuyan T; Jewell C; Kawakita S; Sharma S; Nguyen HT; Najafabadi AH; Ermis M; Falcone N; Chen J
Journal
Small, Vol. 21, No. 1,
Publisher
Wiley
Publication Date
1 2025
DOI
10.1002/smll.202405511
ISSN
1613-6810