Clopidogrel Concept

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• 2014 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation  Journal Articles
• CYP2C19 Genetic Testing Should Not Be Done in All Patients Treated With Clopidogrel Who Are Undergoing Percutaneous Coronary Intervention  Journal Articles
• A population‐based study of the drug interaction between clopidogrel and angiotensin converting enzyme inhibitors  Journal Articles
• A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)  Journal Articles
• Active metabolite concentration of clopidogrel in patients taking different doses of aspirin: results of the interaction trial  Journal Articles
• Adding aspirin to clopidogrel after TIA and ischemic stroke  Journal Articles
• Addition of Clopidogrel to Aspirin and Fibrinolytic Therapy for Myocardial Infarction with ST-Segment Elevation  Journal Articles
• Angina (unstable).  Journal Articles
• Angina (unstable).  Journal Articles
• Antifibrinolytics may be cost saving among recent recipients of combined acetylsalicylic acid and clopidogrel who undergo coronary artery bypass graft surgery.  Journal Articles
• Antiplatelet Therapy and Cardiac Surgery: Review of Recent Evidence and Clinical Implications  Journal Articles
• Antiplatelet Therapy in Cerebral Small Vessel Disease  Journal Articles
• Antiplatelet Therapy in Patients Undergoing Elective Percutaneous Coronary Intervention  Journal Articles
• Antiplatelet drugs  Journal Articles
• Antiplatelet therapy in patients with myocardial infarction without obstructive coronary artery disease  Journal Articles
• Antithrombotic Therapy During Percutaneous Coronary Intervention  Journal Articles
• Antithrombotic Therapy for Atrial Fibrillation  Journal Articles
• Antithrombotic Therapy for Coronary Artery Disease  Journal Articles
• Antithrombotic Therapy for Non–ST-Segment Elevation Acute Coronary Syndromes  Journal Articles
• Antithrombotic Therapy in Patients With Saphenous Vein and Internal Mammary Artery Bypass Grafts  Journal Articles
• Apixaban, an Oral, Direct, Selective Factor Xa Inhibitor, in Combination With Antiplatelet Therapy After Acute Coronary Syndrome  Journal Articles
• Appropriate antiplatelet and antithrombotic therapy in patients with acute coronary syndromes: recent updates to the ACC/AHA guidelines.  Journal Articles
• Are P2Y12 inhibitors superior to aspirin for long-term secondary prevention of cardiovascular disease?  Journal Articles
• Aspirin and Extended-Release Dipyridamole versus Clopidogrel for Recurrent Stroke  Journal Articles
• Aspirin and clopidogrel in patients with ACS undergoing PCI: CURE and PCI-CURE.  Journal Articles
• Aspirin plus clopidogrel was not linked to risk for cancer compared with aspirin alone or no antiplatelets  Journal Articles
• Aspirin resistance: does it exist and is it an important clinical problem?  Journal Articles
• Aspirin to Prevent Cardiovascular Disease: The Association of Aspirin Dose and Clopidogrel With Thrombosis and Bleeding  Journal Articles
• Association between smoking, outcomes, and early clopidogrel use in patients with acute coronary syndrome: Insights from the Global Registry of Acute Coronary Events  Journal Articles
• Baseline characteristics, adenosine diphosphate receptor inhibitor treatment patterns, and in-hospital outcomes of myocardial infarction patients undergoing percutaneous coronary intervention in the prospective Canadian Observational AntiPlatelet sTudy (COAPT)  Journal Articles
• Benefit of Clopidogrel in Patients With Acute Coronary Syndromes Without ST-Segment Elevation in Various Risk Groups  Journal Articles
• Benefit of Oral Anticoagulant Over Antiplatelet Therapy in Atrial Fibrillation Depends on the Quality of International Normalized Ratio Control Achieved by Centers and Countries as Measured by Time in Therapeutic Range  Journal Articles
• Benefit of clopidogrel according to timing of percutaneous coronary intervention in patients with acute coronary syndromes: Further results from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study  Journal Articles
• Benefits and Risks of the Combination of Clopidogrel and Aspirin in Patients Undergoing Surgical Revascularization for Non–ST-Elevation Acute Coronary Syndrome  Journal Articles
• Beyond Heparin and Aspirin  Journal Articles
• CAPRIE trial.  Journal Articles
• Cangrelor With and Without Glycoprotein IIb/IIIa Inhibitors in Patients Undergoing Percutaneous Coronary Intervention  Journal Articles
• Clinical update on the therapeutic use of clopidogrel: treatment of acute ST-segment elevation myocardial infarction (STEMI)  Journal Articles
• Clopidogrel Resistance  Journal Articles
• Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events  Journal Articles
• Clopidogrel and percutaneous coronary intervention  Journal Articles
• Clopidogrel does not suppress blood markers of coagulation activation in aspirin-treated patients with non-ST-elevation acute coronary syndromes  Journal Articles
• Clopidogrel in acute coronary syndromes: Where are we now?  Journal Articles
• Clopidogrel plus aspirin in atrial fibrillation.  Journal Articles
• Clopidogrel plus aspirin versus aspirin alone for acute minor ischaemic stroke or high risk transient ischaemic attack: systematic review and meta-analysis  Journal Articles
• Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial  Journal Articles
• Combination Antiplatelet and Oral Anticoagulant Therapy in Patients With Coronary and Peripheral Artery Disease  Journal Articles
• Comparative Benefits of Clopidogrel and Aspirin in High-Risk Patient Populations  Journal Articles
• Comparison of Dual-antiplatelet Therapy to Mono-antiplatelet Therapy After Transcatheter Aortic Valve Implantation: Systematic Review and Meta-analysis  Journal Articles
• Coronary artery stenting in patients treated by clopidogrel without aspirin  Journal Articles
• Cost-effectiveness of clopidogrel in acute coronary syndromes in Canada: A long-term analysis based on the CURE trial  Journal Articles
• Cost‐effectiveness of clopidogrel in acute coronary syndromes in Sweden: a long‐term model based on the cure trial  Journal Articles
• Current Evidence for Genetic Testing in Clopidogrel-Treated Patients Undergoing Coronary Stenting  Journal Articles
• Design and rationale of CURRENT-OASIS 7: A randomized, 2 × 2 factorial trial evaluating optimal dosing strategies for clopidogrel and aspirin in patients with ST and non–ST-elevation acute coronary syndromes managed with an early invasive strategy  Journal Articles
• Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites  Journal Articles
• Do Patients with Acute Myocardial Infarction Benefit from Treatment with Clopidogrel?  Journal Articles
• Dose Comparisons of Clopidogrel and Aspirin in Acute Coronary Syndromes  Journal Articles
• Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial  Journal Articles
• Double‐Dose Versus Standard‐Dose Clopidogrel According to Smoking Status Among Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention  Journal Articles
• Dual and triple antithrombotic therapies: current patterns of practice and controversies  Journal Articles
• Dual antiplatelet therapy in patients requiring urgent coronary artery bypass grafting surgery: A position statement of the Canadian Cardiovascular Society  Journal Articles
• Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline  Journal Articles
• Early and Late Effects of Clopidogrel in Patients With Acute Coronary Syndromes  Journal Articles
• Effect of PON1 Q192R Genetic Polymorphism on Clopidogrel Efficacy and Cardiovascular Events in the Clopidogrel in the Unstable Angina to Prevent Recurrent Events Trial and the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events  Journal Articles
• Effect of Addition of Clopidogrel to Aspirin on Stroke Incidence: Meta-Analysis of Randomized Trials  Journal Articles
• Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation  Journal Articles
• Effect of Combined Aspirin and Extended-Release Dipyridamole Versus Clopidogrel on Functional Outcome and Recurrence in Acute, Mild Ischemic Stroke  Journal Articles
• Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model  Journal Articles
• Effect of PCI on Quality of Life in Patients with Stable Coronary Disease  Journal Articles
• Effectiveness of platelet inhibition on major adverse cardiac events in non-cardiac surgery after percutaneous coronary intervention: a prospective cohort study  Journal Articles
• Effects of Aspirin Dose When Used Alone or in Combination With Clopidogrel in Patients With Acute Coronary Syndromes  Journal Articles
• Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary Syndromes without ST-Segment Elevation  Journal Articles
• Effects of aspirin dose on ischaemic events and bleeding after percutaneous coronary intervention: insights from the PCI-CURE study  Journal Articles
• Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study  Journal Articles
• Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial  Journal Articles
• Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study  Journal Articles
• Effects of ticagrelor versus clopidogrel on platelet function in fibrinolytic-treated STEMI patients undergoing early PCI  Journal Articles
• Effects ofCYP2C19Genotype on Outcomes of Clopidogrel Treatment  Journal Articles
• Efficacy and safety of cilostazol based triple antiplatelet treatment versus dual antiplatelet treatment in patients undergoing coronary stent implantation: an updated meta-analysis of the randomized controlled trials  Journal Articles
• Efficacy and safety of clopidogrel pretreatment before percutaneous coronary intervention with and without glycoprotein IIb/IIIa inhibitor use  Journal Articles
• Enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized crossover trial  Journal Articles
• Factors predicting reoperation of chronic subdural hematoma following primary surgical evacuation  Journal Articles
• Focused 2012 Update of the Canadian Cardiovascular Society Guidelines for the Use of Antiplatelet Therapy  Journal Articles
• Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin  Journal Articles
• Impact of Clopidogrel Therapy on Mortality and Cancer in Patients With Cardiovascular and Cerebrovascular Disease  Journal Articles
• Impact of Platelet Endothelial Aggregation Receptor-1 Genotypes on Platelet Reactivity and Early Cardiovascular Outcomes in Patients Undergoing Percutaneous Coronary Intervention and Treated With Aspirin and Clopidogrel  Journal Articles
• Impact of combined pharmacologic treatment with clopidogrel and a statin on outcomes of patients with non-ST-segment elevation acute coronary syndromes: perspectives from a large multinational registry  Journal Articles
• Implications of variability in definition and reporting of major bleeding in randomized trials of oral P2Y12 inhibitors for acute coronary syndromes  Journal Articles
• Incidence of Stroke in Paroxysmal Versus Sustained Atrial Fibrillation in Patients Taking Oral Anticoagulation or Combined Antiplatelet Therapy  Journal Articles
• Increased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel  Journal Articles
• Increased long term rates of stent thrombosis and mortality in patients given clopidogrel as compared to ticlopidine following coronary stent implantation  Journal Articles
• Intensified antiplatelet therapy in patients after percutaneous coronary intervention with high on‐treatment platelet reactivity: the OPTImal Management of Antithrombotic Agents (OPTIMA)‐2 Trial  Journal Articles
• Is it safe to use a proton pump inhibitor with clopidogrel?  Journal Articles
• Issues in the management of antiplatelet therapy in patients undergoing surgical revascularization. A roundtable discussion.  Journal Articles
• Letters Regarding Article by Mehilli et al, "Randomized Clinical Trial of Abciximab in Diabetic Patients Undergoing Elective Percutaneous Coronary Interventions After Treatment With a High Loading Dose of Clopidogrel" * Response  Journal Articles
• Level of Systolic Blood Pressure Within the Normal Range and Risk of Recurrent Stroke  Journal Articles
• Long-term cost-effectiveness of clopidogrel given for up to one year in patients with acute coronary syndromes without ST-segment elevation  Journal Articles
• Long-term cost-effectiveness of early and sustained clopidogrel therapy for up to 1 year in patients undergoing percutaneous coronary intervention after presenting with acute coronary syndromes without ST-segment elevation  Journal Articles
• Long-term pharmacodynamic effects of Ticagrelor versus Clopidogrel in fibrinolytic-treated STEMI patients undergoing early PCI  Journal Articles
• Longitudinal treatment patterns with ADP receptor inhibitors after myocardial infarction: Insights from the Canadian Observational AntiPlatelet sTudy  Journal Articles
• Management of Patients with Asymptomatic and Symptomatic Carotid Artery Disease: Update on Anti-Thrombotic Therapy  Journal Articles
• Meta‐analysis: colonoscopic post‐polypectomy bleeding in patients on continued clopidogrel therapy  Journal Articles
• Microbleeds in the Secondary Prevention of Small Subcortical Strokes Trial: Stroke, mortality, and treatment interactions  Journal Articles
• Monitoring the ACTIVE-W trial: Some issues in monitoring a noninferiority trial  Journal Articles
• Mortality predictors and effects of antithrombotic therapies in atrial fibrillation: insights from ACTIVE-W  Journal Articles
• Net Clinical Benefit of Adding Clopidogrel to Aspirin Therapy in Patients With Atrial Fibrillation for Whom Vitamin K Antagonists Are Unsuitable  Journal Articles
• New antithrombotic agents—insights from clinical trials  Journal Articles
• Off-pump coronary artery bypass grafting attenuates postoperative bleeding associated with preoperative clopidogrel administration.  Conferences
• Oral Anticoagulant and Antiplatelet Therapy and Peripheral Arterial Disease  Journal Articles
• Oral Antiplatelet Therapy in Cerebrovascular Disease, Coronary Artery Disease, and Peripheral Arterial Disease  Journal Articles
• Oral antiplatelet therapy.  Journal Articles
• Outcomes Among Clopidogrel, Prasugrel, and Ticagrelor in ST-Elevation Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention From the TOTAL Trial  Journal Articles
• PON1 Q192R genetic variant and response to clopidogrel and prasugrel: pharmacokinetics, pharmacodynamics, and a meta-analysis of clinical outcomes  Journal Articles
• Panax quinquefolium saponin combined with dual antiplatelet drugs inhibits platelet adhesion to injured HUVECs via PI3K/AKT and COX pathways  Journal Articles
• Perioperative Management of Antiplatelet Therapy in Patients With a Coronary Stent Who Need Noncardiac Surgery  Journal Articles
• Perioperative Management of Patients Receiving Anticoagulant or Antiplatelet Therapy: A Clinician-Oriented and Practical Approach  Journal Articles
• Pharmacogenetics of Antiplatelets and Anticoagulants: A Report on Clopidogrel, Warfarin and Dabigatran  Journal Articles
• Pharmacogenomics in Stroke and Cardiovascular Disease: State of the Art  Journal Articles
• Platelet ADP-receptor antagonists for cardiovascular disease: past, present and future  Journal Articles
• Platelet-Active Drugs: The Relationships Among Dose, Effectiveness, and Side Effects  Journal Articles
• Point-of-care Testing for Assessment of Adequacy of Oral Antiplatelet Therapy in Patients With Cardiovascular Disease  Journal Articles
• Predictors of Mortality in Patients With Atrial Fibrillation (from the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events [ACTIVE A])  Journal Articles
• Predictors of Mortality in Patients With Lacunar Stroke in the Secondary Prevention of Small Subcortical Strokes Trial  Journal Articles
• Prevention of coronary heart disease with aspirin and clopidogrel: efficacy, safety, costs and cost-effectiveness  Journal Articles
• Pro: “Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation”  Journal Articles
• Proton Pump Inhibitors and Clopidogrel – Hazardous Drug Interaction or Hazardous Interpretation of Data?  Journal Articles
• Proton pump inhibitor and clopidogrel interaction: The case for watchful waiting  Journal Articles
• Randomized Trial of Warfarin, Aspirin, and Clopidogrel in Patients With Chronic Heart Failure  Journal Articles
• Randomized trial comparing 600- with 300-mg loading dose of clopidogrel in patients with non–ST elevation acute coronary syndrome undergoing percutaneous coronary intervention: Results of the Platelet Responsiveness to Aspirin and Clopidogrel and Troponin Increment after Coronary intervention in Acute coronary Lesions (PRACTICAL) Trial  Journal Articles
• Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting study  Journal Articles
• Rationale and design of ACTIVE: The atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events  Journal Articles
• Rationale and design of the AXIOMATIC-SSP phase II trial: Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute Thromboembolic events for Secondary Stroke Prevention  Journal Articles
• Rationale, Design and Baseline Data of a Randomized, Double-Blind, Controlled Trial Comparing Two Antithrombotic Regimens (a Fixed-Dose Combination of Extended-Release Dipyridamole plus ASA with Clopidogrel) and Telmisartan versus Placebo in Patients with Strokes: The Prevention Regimen for Effectively Avoiding Second Strokes Trial (PRoFESS)  Journal Articles
• Recent Safety Concerns With Proton Pump Inhibitors  Journal Articles
• Relation between clopidogrel active metabolite levels and different platelet aggregation methods in patients receiving clopidogrel and aspirin  Journal Articles
• Relationship Between Degree of Left Ventricular Dysfunction, Symptom Status, and Risk of Embolic Events in Patients With Atrial Fibrillation and Heart Failure  Journal Articles
• Renal function and outcomes in acute coronary syndrome: impact of clopidogrel  Journal Articles
• Response to Ticagrelor in Clopidogrel Nonresponders and Responders and Effect of Switching Therapies  Journal Articles
• Reversal of the antiplatelet effect of ticagrelor by simulated platelet transfusion  Journal Articles
• Reversal of the anti‐platelet effects of aspirin and clopidogrel  Journal Articles
• Review of aspirin and clopidogrel resistance in peripheral arterial disease  Journal Articles
• Risks and Benefits of Oral Anticoagulation Compared With Clopidogrel Plus Aspirin in Patients With Atrial Fibrillation According to Stroke Risk  Journal Articles
• Rivaroxaban Plus Aspirin Versus Aspirin Alone After Endovascular Revascularization for Symptomatic PAD: Insights From VOYAGER PAD  Journal Articles
• Rivaroxaban and Aspirin in Peripheral Artery Disease Lower Extremity Revascularization  Journal Articles
• Rivaroxaban and Risk of Venous Thromboembolism in Patients With Symptomatic Peripheral Artery Disease After Lower Extremity Revascularization  Journal Articles
• Role of phenotypic and genetic testing in managing clopidogrel therapy  Journal Articles
• Role of triple antithrombotic therapy in patients with atrial fibrillation and coronary artery stents  Journal Articles
• Short- and long-term oral antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention  Journal Articles
• Single or Dual Antiplatelet Treatment after TAVI  Journal Articles
• State of the Art-A Journey through the World of Antithrombotic Therapy  Journal Articles
• Temporal trends and patterns of early clopidogrel use across the spectrum of acute coronary syndromes  Journal Articles
• The CHA2DS2-VASc score identifies those patients with atrial fibrillation and a CHADS2 score of 1 who are unlikely to benefit from oral anticoagulant therapy  Journal Articles
• The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme. Rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease  Journal Articles
• The Cost of Clopidogrel Use in Atrial Fibrillation in the ACTIVE-A Trial  Journal Articles
• The Evolution of Antiplatelet Therapy After Percutaneous Coronary Interventions: A 40-Year Journey  Journal Articles
• The Interaction Between Proton Pump Inhibitors and Clopidogrel and Upper Gastrointestinal Bleeding  Journal Articles
• The Perioperative Management of Antithrombotic Therapy  Journal Articles
• The Primary and Secondary Prevention of Coronary Artery Disease  Journal Articles
• The Pursuit of Clinically Relevant Measures of Platelet Function After Antiplatelet Drug Therapy⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.  Journal Articles
• The Relative Efficacy and Safety of Clopidogrel in Women and Men  Journal Articles
• The Secondary Prevention of Small Subcortical Strokes (SPS3) Study  Journal Articles
• The Warfarin and Antiplatelet Therapy in Heart Failure Trial (WATCH): rationale, design, and baseline patient characteristics  Journal Articles
• The cost-effectiveness of the use of clopidogrel in acute coronary syndromes in five countries based upon the CURE study.  Journal Articles
• The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect  Journal Articles
• The relationship between CYP2C19 polymorphisms and ischaemic and bleeding outcomes in stable outpatients: the CHARISMA genetics study  Journal Articles
• The role of platelets and platelet inhibition in acute myocardial infarction  Journal Articles
• There seems to be a low risk of experiencing postoperative bleeding in patients undergoing dental extractions or minor oral surgery who continue using antiplatelet therapy  Journal Articles
• Thromboembolic events around the time of cardioversion for atrial fibrillation in patients receiving antiplatelet treatment in the ACTIVE trials  Journal Articles
• Thrombolysis and Adjunctive Therapy in Acute Myocardial Infarction  Conferences
• Ticagrelor versus clopidogrel in real-world patients with ST elevation myocardial infarction: 1-year results by propensity score analysis  Journal Articles
• Treatment of Acute Coronary Syndromes  Journal Articles
• Trends in Incidence of Intracerebral Hemorrhage and Association With Antithrombotic Drug Use in Denmark, 2005-2018  Journal Articles
• Underutilization of clopidogrel and glycoprotein IIb/IIIa inhibitors in non–ST-elevation acute coronary syndrome patients: The Canadian Global Registry of Acute Coronary Events (GRACE) experience  Journal Articles
• Use of Clopidogrel Post-Coronary Artery Bypass Surgery in Canadian Patients With Acute Coronary Syndromes  Journal Articles
• Valsartan combined with clopidogrel and/or leflunomide for the treatment of progressive immunoglobulin A nephropathy  Journal Articles
• Warfarin after anterior myocardial infarction in current era of dual antiplatelet therapy: a randomized feasibility trial  Journal Articles
• When guidelines collide  Journal Articles
• Will prasugrel supersede clopidogrel for acute coronary syndromes?  Journal Articles