Journal article
Addition of Clopidogrel to Aspirin and Fibrinolytic Therapy for Myocardial Infarction with ST-Segment Elevation
Abstract
BACKGROUND: A substantial proportion of patients receiving fibrinolytic therapy for myocardial infarction with ST-segment elevation have inadequate reperfusion or reocclusion of the infarct-related artery, leading to an increased risk of complications and death.
METHODS: We enrolled 3491 patients, 18 to 75 years of age, who presented within 12 hours after the onset of an ST-elevation myocardial infarction and randomly assigned them to receive …
Authors
Sabatine MS; Cannon CP; Gibson CM; López-Sendón JL; Montalescot G; Theroux P; Claeys MJ; Cools F; Hill KA; Skene AM
Journal
The New England Journal of Medicine, Vol. 352, No. 12, pp. 1179–1189
Publisher
Massachusetts Medical Society
Publication Date
March 24, 2005
DOI
10.1056/nejmoa050522
ISSN
0028-4793
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedAngioplasty, Balloon, CoronaryAspirinClopidogrelCoronary AngiographyCoronary Artery BypassDrug Therapy, CombinationElectrocardiographyFemaleFibrinolytic AgentsHemorrhageHeparinHumansMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsSecondary PreventionThrombolytic TherapyTiclopidineVascular Patency