Journal article
Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation
Abstract
BACKGROUND: Vitamin K antagonists reduce the risk of stroke in patients with atrial fibrillation but are considered unsuitable in many patients, who usually receive aspirin instead. We investigated the hypothesis that the addition of clopidogrel to aspirin would reduce the risk of vascular events in patients with atrial fibrillation.
METHODS: A total of 7554 patients with atrial fibrillation who had an increased risk of stroke and for whom …
Authors
Connolly SJ; Pogue J; Hart RG; Hohnloser SH; Pfeffer M; Chrolavicius S; Yusuf S
Journal
The New England Journal of Medicine, Vol. 360, No. 20, pp. 2066–2078
Publisher
Massachusetts Medical Society
Publication Date
May 14, 2009
DOI
10.1056/nejmoa0901301
ISSN
0028-4793