Journal article
Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial
Abstract
BACKGROUND: Clopidogrel and aspirin are the most commonly used antiplatelet therapies for percutaneous coronary intervention (PCI). We assessed the effect of various clopidogrel and aspirin regimens in prevention of major cardiovascular events and stent thrombosis in patients undergoing PCI.
METHODS: The CURRENT-OASIS 7 trial was undertaken in 597 centres in 39 countries. 25,086 individuals with acute coronary syndromes and intended early PCI …
Authors
Mehta SR; Tanguay J-F; Eikelboom JW; Jolly SS; Joyner CD; Granger CB; Faxon DP; Rupprecht H-J; Budaj A; Avezum A
Journal
The Lancet, Vol. 376, No. 9748, pp. 1233–1243
Publisher
Elsevier
Publication Date
October 2010
DOI
10.1016/s0140-6736(10)61088-4
ISSN
0140-6736