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Randomized Trial of Warfarin, Aspirin, and...
Journal article

Randomized Trial of Warfarin, Aspirin, and Clopidogrel in Patients With Chronic Heart Failure

Abstract

BACKGROUND: Chronic heart failure remains a major cause of mortality and morbidity. The role of antithrombotic therapy in patients with chronic heart failure has long been debated. The objective of this study was to determine the optimal antithrombotic agent for heart failure patients with reduced ejection fractions who are in sinus rhythm. METHODS AND RESULTS: This prospective, randomized clinical trial of open-label warfarin (target …

Authors

Massie BM; Collins JF; Ammon SE; Armstrong PW; Cleland JGF; Ezekowitz M; Jafri SM; Krol WF; O'Connor CM; Schulman KA

Journal

Circulation, Vol. 119, No. 12, pp. 1616–1624

Publisher

Wolters Kluwer

Publication Date

March 31, 2009

DOI

10.1161/circulationaha.108.801753

ISSN

0009-7322